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SOD1 Protein Human Proteins Molecular Depot
SOD1 Protein Human Proteins Molecular Depot
SOD1 Protein Human Proteins Molecular Depot
SOD1 Protein Human Proteins Molecular Depot

SOD1 Protein Human

$795.00

    Catalog Number: B2013808 (50 ug)

    SOD1 Protein Human is a high quality SOD1 (superoxide dismutase 1), human. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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SOD1 Protein Human – Catalog Number: B2013808 (50 ug)

Catalog number: B2013808
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 ug
Molecular Weight or Concentration: 45 kDa
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: ALS, ALS1, Cu/Zn-SOD, Homodimer, IPOA, SOD
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

SOD1 Protein Human provides a solution-format preparation of superoxide dismutase 1 (SOD1) in a defined 50 ug fill (Catalog B2013808) with storage at −20 °C. The listing documents a 45 kDa entry under “Molecular Weight or Concentration” and identifies the material as a molecular tool for various biochemical applications. SOD1 catalyzes the dismutation of superoxide radicals to oxygen and hydrogen peroxide, and research groups often incorporate SOD1 into qualitative assays or training exercises centered on oxidative stress biology, protein stability, or interaction studies. The concise specification set—amount, supplied-as, storage, keyword identity, and biotechnology-grade note—supports SOP inclusion and inventory traceability in multi-user labs.

Because this product is supplied as a solution, it integrates directly into pilot experiments without the variability of reconstitution steps. When setting up workflows—such as affinity-based capture, interaction mapping, or stress-challenge incubations—good bench practice is to document buffer composition (pH, ionic strength, additives), incubation time and temperature, and time-at-temperature during handling. Recording these parameters alongside lot identifiers helps ensure reproducibility across analysts and instruments and simplifies later method transfer. The keyword set provided on the listing (including ALS-related terms) offers convenient anchors for LIMS/SOP indexing when SOD1 is used in model-system studies or instructional demonstrations.

Typical research scenarios include exploratory evaluations of SOD1 behavior under varying buffer conditions; qualitative interaction screens where SOD1 serves as a binding partner of interest; and benchtop demonstrations that link oxidative processes to enzyme-based readouts. Since no activity units or working concentrations are prescribed in the listing, a practical approach is to begin with small-scale titrations tailored to your matrix and detection chemistry, establish a baseline signal window, and then lock those conditions for repeat testing. Within research-only boundaries, this solution-format SOD1 offering is a clearly specified, documentation-friendly component for laboratories standardizing SOD1-related studies or teaching modules.

Why researchers choose this product:

  • Defined 50 ug fill in ready-to-use solution format streamlines setup
  • Listing includes a 45 kDa entry for straightforward record-keeping
  • Specified storage at −20 °C fits routine cold-chain handling
  • Designated as a molecular tool for diverse biochemical applications
  • ALS-related keywords aid SOP/LIMS mapping for oxidative-stress model work

This product is for Research Use Only (RUO). It is not intended for diagnostic or therapeutic use.

References

  • 1: McCampbell A, Cole T, Wegener AJ, Tomassy GS, Setnicka A, Farley BJ, Schoch KM, Hoye ML, Shabsovich M, Sun L, Luo Y, Zhang M, Comfort N, Wang B, Amacker J, Thankamony S, Salzman DW, Cudkowicz M, Graham DL, Bennett CF, Kordasiewicz HB, Swayze EE, Miller TM. Antisense oligonucleotides extend survival and reverse decrement in muscle response in ALS models J Clin Invest. 2018 Aug 1;128(8):3558-3567.
  • 2: Gupta U, Ghosh S, Wallace CT, Shang P, Xin Y, Nair AP, Yazdankhah M, Strizhakova A, Ross MA, Liu H, Hose S, Stepicheva NA, Chowdhury O, Nemani M, Maddipatla V, Grebe R, Das M, Lathrop KL, Sahel JA, Zigler JS Jr, Qian J, Ghosh A, Sergeev Y, Handa JT, St Croix CM, Sinha D. Increased LCN2 (lipocalin 2) in the RPE decreases autophagy and activates inflammasome-ferroptosis processes in a mouse model of dry AMD Autophagy. 2023 Jan;19(1):92-111.
  • 3: Pan J, Wu L, He H, Chen L, Su Y, Li L, Liu S. [Expression, purification, stability and transduction efficiency of GST-SOD1-R9 fusion protein] Sheng Wu Gong Cheng Xue Bao. 2017 May 25;33(5):828-837.
  • 4: Yuan H, Xia P, Sun X, Ma J, Xu X, Fu C, Zhou H, Guan Y, Li Z, Zhao S, Wang H, Dai L, Xu C, Dong S, Geng Q, Li Z, Wang J. Photothermal Nanozymatic Nanoparticles Induce Ferroptosis and Apoptosis through Tumor Microenvironment Manipulation for Cancer Therapy Small. 2022 Oct;18(41):e2202161.
  • 5: Dai JM, Guo WN, Tan YZ, Niu KW, Zhang JJ, Liu CL, Yang XM, Tao KS, Chen ZN, Dai JY. Wogonin alleviates liver injury in sepsis through Nrf2-mediated NF-B signalling suppression J Cell Mol Med. 2021 Jun;25(12):5782-5798.
  • 6: Bovio F, Sciandrone B, Urani C, Fusi P, Forcella M, Regonesi ME. Superoxide dismutase 1 (SOD1) and cadmium: A three models approach to the comprehension of its neurotoxic effects Neurotoxicology. 2021 May;84:125-135.
  • 7: He H, Lin L, Li L, Wu L, Lin H, Pan J. [Expression, purification, and characterization of cell-permeable fusion antioxidant enzyme sensitive to matrix metalloproteinases-2/9] Sheng Wu Gong Cheng Xue Bao. 2022 Sep 25;38(9):3515-3527.
  • 8: De Marco G, Conti GO, Giannetto A, Cappello T, Galati M, Iaria C, Pulvirenti E, Capparucci F, Mauceri A, Ferrante M, Maisano M. Embryotoxicity of polystyrene microplastics in zebrafish Daniorerio Environ Res. 2022 May 15;208:112552.
  • 9: Aydemir D, Malik AN, Kulac I, Basak AN, Lazoglu I, Ulusu NN. Impact of the Amyotrophic Lateral Sclerosis Disease on the Biomechanical Properties and Oxidative Stress Metabolism of the Lung Tissue Correlated With the Human Mutant SOD1(G93A) Protein Accumulation Front Bioeng Biotechnol. 2022 Feb 25;10:810243.
  • 10: Kamierczak B, Kuma-Kozakiewicz M, Usarek E, Baraczyk-Kuma A. Differences in glutathione S-transferase pi expression in transgenic mice with symptoms of neurodegeneration Acta Biochim Pol. 2011;58(4):621-6. Epub 2011 Nov 30. pubmed.ncbi.nlm.nih.gov

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Product Resources:

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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