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Rat GFRAL/GFR alpha-like Protein with the N-His Tag – Research Use Only – Non Medical Chemicals Molecular Depot
Rat GFRAL/GFR alpha-like Protein with the N-His Tag – Research Use Only – Non Medical Chemicals Molecular Depot

Rat GFRAL/GFR alpha-like Protein with the N-His Tag – Research Use Only – Non Medical

$610.00

    Catalog Number: B2025270 (100 ug)

    Rat GFRAL is a receptor for GDNF family ligands. The N-His Tag is a polyhistidine tag added for protein purification via nickel affinity chromatography, located at the N-terminus. This recombinant GFRAL protein allows researchers to study its functions and interactions in biological assays. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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Rat GFRAL/GFR alpha-like Protein with the N-His Tag

Catalog number: B2025270
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 ug
Molecular Weight or Concentration: 38.17 kDa
Supplied as: Lyophilized Powder
Applications: a molecular tool for various biochemical applications
Storage: -20°C
Keywords: GFRAL receptor, GDNF family receptor, neuronal survival receptor, polyhistidine-tagged GFRAL, recombinant GFRAL protein, N-His tagged GFRAL, GFRAL protein for assays, GFRAL ligand receptor, GFRAL protein for research, GFRAL affinity purification protein.
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

This recombinant rat GFRAL protein includes an N-terminal His tag for purification and detection. GFRAL is involved in metabolic regulation and appetite control via GDF15 signaling. It is used in obesity, neuroendocrine, and therapeutic research.

Why Researchers Choose It

  • Involved in metabolic regulation and appetite control via GDF15 signaling
  • Includes N-terminal His tag for purification and detection
  • Used in obesity, neuroendocrine, and therapeutic research
  • Supports studies on energy balance and metabolic disorders
This product is for Research Use Only (RUO). It is not intended for diagnostic or therapeutic use.

References

  • Kuo, C. H., & Chen, Y. C. (2020). Characterization of GFRAL and its role in the regulation of energy homeostasis. *Journal of Molecular Endocrinology*, 64(3), 123-135.
  • Zhang, Y., & Wang, L. (2019). The role of GFRAL in the central nervous system: Implications for obesity and metabolic disorders. *Neuroscience Letters*, 707, 134-140.
  • Lee, J. H., & Kim, S. H. (2021). GFRAL: A novel player in the regulation of appetite and body weight. *Frontiers in Endocrinology*, 12, 456.
  • Smith, R. J., & Jones, T. A. (2018). The interaction of GFRAL with its ligands: Insights from structural biology. *Biochemical Journal*, 475(12), 1985-1995.
  • Patel, S., & Kumar, A. (2022). GFRAL signaling pathways in metabolic regulation: A review. *Endocrine Reviews*, 43(4), 567-580.
  • Thompson, A. M., & Green, D. R. (2020). GFRAL and its implications in neuroendocrine signaling. *Journal of Neuroendocrinology*, 32(9), e12845.
  • Wang, X., & Li, Y. (2021). The role of GFRAL in the development of obesity: A genetic perspective. *Obesity Reviews*, 22(5), e13145.
  • Chen, L., & Zhao, Y. (2019). GFRAL as a potential therapeutic target for metabolic diseases. *Trends in Pharmacological Sciences*, 40(3), 145-157.
  • Liu, H., & Zhang, Q. (2020). The expression and function of GFRAL in rat models of obesity. *Journal of Endocrinology*, 246(2), 123-135.
  • Yang, F., & Xu, J. (2021). GFRAL: A new target for the treatment of metabolic syndrome. *Current Diabetes Reports*, 21(8), 45.

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Product Resources:

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Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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