Palmitoleic Acid (Highly Pure) – Catalog #B2018754 (100 mg)

Endogenous omega-7 monounsaturated fatty acid for metabolic regulation, anti-inflammatory, and biochemical research. Palmitoleic Acid (Highly Pure) (Catalog #B2018754, 100 mg) is a biotechnology-grade omega-7 fatty acid notable for its regulatory roles in metabolism, inflammation, and gut health. Supplied as a stabilized solution, this molecular tool enables consistent application in cellular and biochemical assays exploring lipid biology, immune modulation, and disease mechanisms.

Emerging evidence highlights palmitoleic acid's capacity to influence gut microbiota composition and enhance therapeutic outcomes in colitis models, indicating its potential in metabolic inflammatory disease research. It also modulates immune activity and metabolic regulation via its positional isomers—such as hypogeic and sapienic acids—making it a versatile reagent for dissecting nuanced lipid-mediated signaling pathways. Its use supports lipid profiling, cell membrane dynamics studies, and enzymatic pathways across immunometabolic systems.

Produced under rigorous biotech-grade conditions with ultrapure water and microfiltration, this compound ensures experimental reproducibility and minimal contaminant interference—critical for translational and mechanistic research. Stored at –20 °C, the solution offers long-term stability, and bulk quantity options are available for scaling investigations. Whether applied in metabolism, inflammation, or lipid signaling studies, this reagent supports high-precision lipidomics research.

Why researchers choose this product:

• Endogenous lipid with physiological and therapeutic relevance in metabolic and inflammatory pathways
• High-purity, biotech-grade solution supports sensitive biochemical assays
• Stabilized format with cold storage ensures longevity and dosing accuracy
• Ideal for gut microbiome, immunometabolic, and signaling research
• Scalable quantities available to support extended study designs

Indication for Use:
This product is intended for Research Use Only (RUO). It is not for diagnostic, therapeutic, or clinical applications.

References:

• Chen Y, Mai Q, Chen Z, Lin T, Cai Y, Han J, Wang Y, Zhang M, Tan S, Wu Z, Chen L, Zhang Z, Yang Y, Cui T, Ouyang B, Sun Y, Yang L, Xu L, Zhang S, Li J, Shen H, Liu L, Zeng L, Zhang S, Zeng G. Dietary palmitoleic acid reprograms gut microbiota and improves biological therapy against colitis Gut Microbes. 2023 Jan-Dec;15(1):2211501.
• Bermúdez MA, Pereira L, Fraile C, Valerio L, Balboa MA, Balsinde J. Roles of Palmitoleic Acid and Its Positional Isomers, Hypogeic and Sapienic Acids, in Inflammation, Metabolic Diseases and Cancer Cells. 2022 Jul 8;11(14):2146.
• Guillocheau E, Legrand P, Rioux V. Trans-palmitoleic acid (trans-9-C16:1, or trans-C16:1 n-7): Nutritional impacts, metabolism, origin, compositional data, analytical methods and chemical synthesis. A review Biochimie. 2020 Feb;169:144-160.
• de Souza CO, Vannice GK, Rosa Neto JC, Calder PC. Is Palmitoleic Acid a Plausible Nonpharmacological Strategy to Prevent or Control Chronic Metabolic and Inflammatory Disorders? Mol Nutr Food Res. 2018 Jan;62(1).
• Tsai YW, Lu CH, Chang RC, Hsu YP, Ho LT, Shih KC. Palmitoleic acid ameliorates palmitic acid-induced proinflammation in J774A.1 macrophages via TLR4-dependent and TNF-α-independent signallings Prostaglandins Leukot Essent Fatty Acids. 2021 Jun;169:102270.
• Frigolet ME, Gutiérrez-Aguilar R. The Role of the Novel Lipokine Palmitoleic Acid in Health and Disease Adv Nutr. 2017 Jan 17;8(1):173S-181S.
• Nunes EA, Rafacho A. Implications of Palmitoleic Acid (Palmitoleate) On Glucose Homeostasis, Insulin Resistance and Diabetes Curr Drug Targets. 2017;18(6):619-628.
• Tang J, Yang B, Yan Y, Tong W, Zhou R, Zhang J, Mi J, Li D. Palmitoleic Acid Protects against Hypertension by Inhibiting NF-κB-Mediated Inflammation Mol Nutr Food Res. 2021 Jun;65(12):e2001025.
• Ku L, Lee J, Lim JW, Jin L, Seo JT, Kim H. Docosahexaenoic acid inhibits ethanol/palmitoleic acid-induced necroptosis in AR42J cells J Physiol Pharmacol. 2020 Jun;71(3).
• 10: Yamamoto Y. [Palmitoleic acid] Nihon Rinsho. 2005 Aug;63 Suppl 8:803-5.