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DYRK2 Protein, Active Proteins Molecular Depot
DYRK2 Protein, Active Proteins Molecular Depot

DYRK2 Protein, Active

$2,395.00

    Catalog Number: B2019370 (5  µg)

    DYRK2 (Dual-specificity tyrosine-phosphorylation-regulated kinase 2) is a protein kinase involved in cellular processes such as cell cycle regulation and apoptosis. It phosphorylates serine/threonine and tyrosine residues, influencing various pathways. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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What's Included

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VR Headset

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2 Touch Controllers

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Charging Cable

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Power Adapter

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Glasses Spacer

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DYRK2 Protein, Active

Catalog number: B2019370
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 µg
Molecular Weight or Concentration: 63.5 kDa
Supplied as: Resin
Applications: a molecular tool for various biochemical applications
Storage: −70°C
Keywords: DYRK2 Protein, Active
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References

  • Tandon V, de la Vega L, Banerjee S. Emerging roles of DYRK2 in cancer J Biol Chem. 2021 Jan-Jun;296:100233.
  • Jiménez-Izquierdo R, Morrugares R, Suanes-Cobos L, Correa-Sáez A, Garrido-Rodríguez M, Cerero-Tejero L, Khan OM, de la Luna S, Sancho R, Calzado MA. FBXW7 tumor suppressor regulation by dualspecificity tyrosine-regulated kinase 2 Cell Death Dis. 2023 Mar 18;14(3):202.
  • Kamioka H, Yogosawa S, Oikawa T, Aizawa D, Ueda K, Saeki C, Haruki K, Shimoda M, Ikegami T, Nishikawa Y, Saruta M, Yoshida K. Dyrk2 gene transfer suppresses hepatocarcinogenesis by promoting the degradation of Myc and Hras JHEP Rep. 2023 Apr 6;5(7):100759.
  • VerPlank JJS, Goldberg AL. Regulating protein breakdown through proteasome phosphorylation Biochem J. 2017 Sep 24;474(19):3355-3371.
  • Lara-Chica M, Correa-Sáez A, Jiménez-Izquierdo R, Garrido-Rodríguez M, Ponce FJ, Moreno R, Morrison K, Di Vona C, Arató K, Jiménez-Jiménez C, Morrugares R, Schmitz ML, de la Luna S, de la Vega L, Calzado MA. A novel CDC25A/DYRK2 regulatory switch modulates cell cycle and survival Cell Death Differ. 2022 Jan;29(1):105-117.
  • Kawamura A, Yoshida S, Yoshida K. The diverse functions of DYRK2 in response to cellular stress Histol Histopathol. 2024 Nov;39(11):1427-1434.
  • Moreno R, Banerjee S, Jackson AW, Quinn J, Baillie G, Dixon JE, Dinkova-Kostova AT, Edwards J, de la Vega L. The stress-responsive kinase DYRK2 activates heat shock factor 1 promoting resistance to proteotoxic stress Cell Death Differ. 2021 May;28(5):1563-1578.
  • Yoshida S, Kawamura A, Aoki K, Wiriyasermkul P, Sugimoto S, Tomiyoshi J, Tajima A, Ishida Y, Katoh Y, Tsukada T, Tsuneoka Y, Yamada K, Nagamori S, Nakayama K, Yoshida K. Positive regulation of Hedgehog signaling via phosphorylation of GLI2/GLI3 by DYRK2 kinase Proc Natl Acad Sci U S A. 2024 Jul 9;121(28):e2320070121.
  • Sun Y, Ge X, Li M, Xu L, Shen Y. Dyrk2 involved in regulating LPS-induced neuronal apoptosis Int J Biol Macromol. 2017 Nov;104(Pt A):979-986.

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    Blue Tiger Scientific is an independent third-party distributor of select products manufactured by Molecular Depot LLC. By purchasing from bluetigerscientific.com, you (“the Customer”) agree to the following terms, adapted from Molecular Depot’s original conditions:

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    Products are for in vitro research use only (RUO). They are not intended for human or animal use, diagnosis, therapy, resale to consumers, or residential delivery. Sales are limited to verified business addresses.

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Product Resources:

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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