DTPA (Highly Pure) – Research Use Only

DTPA (Diethylenetriaminepentaacetic Acid), Highly Pure, is a biotechnology-grade chelating reagent supplied as a lyophilized powder for research applications requiring strong sequestration of multivalent metal ions. This reagent is widely used in biochemical and analytical workflows involving metal ion chelation, trace metal control, metalloprotein studies, and radiochemistry-related coordination systems. Its high metal-binding capacity makes it valuable in experiments where precise regulation of free metal ion availability is essential.

Scientific Overview

DTPA is a polyaminocarboxylic acid chelator known for its strong affinity toward a broad range of divalent and trivalent metal ions. In research settings, it is commonly used to reduce interference from trace metals, regulate metal-dependent reactions, and support workflows where metal sequestration improves reproducibility or prevents unwanted catalytic activity.

This highly pure DTPA preparation is suitable for:

• Preparation of metal-controlled or metal-depleted assay systems
• Inhibition or modulation of metal-dependent enzymes and reactions
• Analytical and environmental chemistry workflows involving heavy metal binding
• Radiochemistry and coordination studies involving metal-chelate complexes
• Buffer preparation for sensitive biochemical and molecular biology applications

Usage & Handling Guidance

Store the lyophilized powder at -20°C. Reconstitute in suitable water or buffer according to your application, and adjust pH as needed to improve solubility and chelation performance. For trace metal-sensitive workflows, use clean, low-metal labware and freshly prepared solutions whenever possible.

• Recommended applications: Metal ion chelation, buffer preparation, trace metal control, and coordination chemistry research
• Preparation: Dissolve in appropriate solvent and optimize pH for intended use
• Handling: Use clean containers to minimize unintended metal contamination
• Storage after reconstitution: Optimize according to concentration, solvent, and workflow requirements

What You Get

• 5 g of DTPA (Highly Pure)
• Lyophilized powder format for flexible research use
• Biotechnology-grade reagent suitable for biochemical and analytical workflows
• High-purity material for controlled metal chelation applications
• For research use only (RUO)

Why Researchers Choose It

• Strong and reliable chelation of multivalent metal ions
• Useful for reducing trace metal interference in sensitive experiments
• Supports biochemical, analytical, environmental, and coordination chemistry workflows
• Lyophilized format offers flexibility for custom solution preparation
• High-purity biotechnology-grade material for reproducible laboratory use

Frequently Asked Questions (FAQ)

• What is DTPA used for in research?
  DTPA is primarily used as a metal chelator in workflows that require sequestration of divalent or trivalent metal ions, including trace metal control, metalloprotein studies, analytical chemistry, and coordination research.
• What form is this product supplied in?
  This product is supplied as a lyophilized powder, allowing researchers to prepare solutions at concentrations appropriate for their specific protocols.
• Why might pH adjustment be needed during preparation?
  Chelating agents such as DTPA may dissolve more effectively after pH adjustment, depending on solvent system and target concentration.
• Can this reagent be used to prepare metal-free buffers?
  It is commonly used in workflows designed to reduce free metal ion interference, including preparation of metal-controlled buffer systems for sensitive assays.
• How should this product be stored?
  Store the lyophilized powder at -20°C. Storage conditions after reconstitution should be optimized based on the prepared formulation and intended use.

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References

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