Skip to content
Collagenase from Clostridium Histolyticum Proteins Molecular Depot
Collagenase from Clostridium Histolyticum Proteins Molecular Depot
Collagenase from Clostridium Histolyticum Proteins Molecular Depot
Collagenase from Clostridium Histolyticum Proteins Molecular Depot

Collagenase from Clostridium Histolyticum

$595.00

    Catalog Number: B2019027 (50 mg)


    Collagnase, Clostridium histolyticum is an enzyme from the bacterium Clostridium histolyticum that breaks down collagen, a key structural protein in connective tissues. It cleaves peptide bonds in collagen, leading to the breakdown of collagen fibers. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

    Live Inquiry about this product via:

    Email: info@bluetigerscientific.com

    Text/SMS: (833) 928-4437 Mon–Fri, (8 am – 8 pm PST)

See All Specs

aeroplane.png__PID:119d4b1a-2623-400c-8fa4-aec5b49a3bf0

Fast Delivery

Most items ship same day

protection.png__PID:4b1a2623-e00c-4fa4-aec5-b49a3bf05f92

Manufacturer Warranty

All products are covered by manufacturer warranty

technical-support.png__PID:e00c8fa4-aec5-449a-bbf0-5f923431936b

After-Sale Support

24/7 support

What's Included

download (70).webp__PID:7ab0a366-c50a-41ee-ae3a-ab9ed2dfc0ad

VR Headset

download (71).webp__PID:547ab0a3-66c5-4a41-aeae-3aab9ed2dfc0

2 Touch Controllers

download (72).webp__PID:dc547ab0-a366-450a-81ee-ae3aab9ed2df

Charging Cable

download (72).webp__PID:dc547ab0-a366-450a-81ee-ae3aab9ed2df

Power Adapter

download (72).webp__PID:dc547ab0-a366-450a-81ee-ae3aab9ed2df

Glasses Spacer

download (69).webp__PID:26576cae-f878-4c99-ab7c-894d76af129b

Collagenase from Clostridium histolyticum – Catalog #B2019027 (50 mg)

Catalog # B2019027
Lot # Batch dependent
Expiration Batch dependent
Amount 50 mg
Supplied As Powder
Applications Biochemical and immunological tool for collagen degradation
Storage 2–8 °C
Grade Biotechnology grade; ultrapure Type I water; 0.22 µm filtered
Keywords Collagenase Clostridium histolyticum, collagenase enzyme, matrix digestion

Versatile collagenase for efficient and reproducible matrix digestion in RUO research. Collagenase from *Clostridium histolyticum* (Catalog #B2019027, 50 mg) is a high-purity enzyme preparation widely used to degrade extracellular collagen in a wide range of biochemical and immunological applications. Its robust activity facilitates downstream workflows such as tissue dissociation, extracellular matrix remodeling, and proteomic analysis. Supplied as a stable powder, it supports precise dosing and reliable enzymatic performance in RUO environments.

This bacterial collagenase targets and cleaves peptide bonds in collagen fibers, enabling efficient breakdown of connective tissue matrices for applications in cell isolation, structural biology, and ECM studies. Researchers routinely rely on this enzyme to prepare single-cell suspensions, analyze collagen turnover, or standardize digestion in comparative experiments. The easy-to-store powder format maintains enzymatic activity under proper conditions (2–8 °C), simplifying inventory management and experimental planning.

Manufactured to biotechnology-grade standards, including ultrapure water preparation and 0.22 µm filtration, this collagenase ensures low background and reproducibility. Custom bulk quantities are available for scale-up or ongoing project needs. Whether your work involves immunohistochemistry, protease profiling, decellularization, or matrix analysis, this collagenase offers dependable enzymatic performance laboratory-wide.

Why researchers choose this product:

  • Efficient collagen degradation for tissue dissociation and ECM studies
  • High-purity, consistently sourced enzyme for reliable RUO use
  • Stable powdered form simplifies storage and concentration control
  • Validated preparation with ultrapure water and microfiltration
  • Custom bulk options available for scalable workflows

Indication for Use:
This enzyme is for Research Use Only (RUO). It is not intended for clinical, diagnostic, or therapeutic use.

References:

  • Hoy SM. Collagenase Clostridium histolyticum: A Review in Peyronie’s Disease. Clin Drug Investig. 2020 Jan;40(1):83–92.
  • Smeraglia F, Del Buono A, Maffulli N. Collagenase clostridium histolyticum in Dupuytren’s contracture: a systematic review. Br Med Bull. 2016 Jun;118(1):149–58.
  • Abdel Raheem A, Johnson M, Ralph D, Garaffa G. Collagenase clostridium histolyticum: a novel medical treatment for Peyronie’s disease. Minerva Urol Nefrol. 2018 Aug;70(4):380–385.
  • Greear GM, Koprowski CJ, Hsieh TC. Managing complications of collagenase Clostridium histolyticum (CCH) injection. World J Urol. 2020 Feb;38(2):287–292.
  • Warwick D, Arandes-Renú JM, Pajardi G, Witthaut J, Hurst LC. Collagenase Clostridium histolyticum: emerging practice patterns and treatment advances. J Plast Surg Hand Surg. 2016 Oct;50(5):251–60.
  • Gabrielson AT, Spitz JT, Hellstrom WJG. Collagenase Clostridium histolyticum in the Treatment of Urologic Disease: Current and Future Impact. Sex Med Rev. 2018 Jan;6(1):1–56.
  • Amighi A, Eleswarapu SV, Mendhiratta N, Nork JJ, Mills JN. Discontinuation from Collagenase Clostridium histolyticum Therapy for Peyronie’s Disease: Review and Single-Center Cohort Analysis. Sex Med Rev. 2019 Oct;7(4):690–698.
  • Liechti R, Merky DN, Sutter D, Ipaktchi R, Vögelin E. Collagenase clostridium histolyticum injection versus limited fasciectomy for the treatment of Dupuytren’s disease: a systematic review and meta-analysis of comparative studies. Arch Orthop Trauma Surg. 2024 Jan;144(1):527–536.
  • Green B, Flores A, Warner J, Kohler T, Helo S, Trost L. Comparison of Collagenase Clostridium histolyticum to Surgery for the Management of Peyronie’s Disease: A Randomized Trial. J Urol. 2023 Nov;210(5):791–802.
  • Furtado TP, Osadchiy V, Andino JJ, Eleswarapu SV, Mills JN. Collagenase Clostridium histolyticum for Peyronie’s disease: a contemporary atlas of complications and their management. Sex Med Rev. 2024 Jun 26;12(3):1–12.

    Terms & Conditions

    Blue Tiger Scientific is an independent third-party distributor of select products manufactured by Molecular Depot LLC. By purchasing from bluetigerscientific.com, you (“the Customer”) agree to the following terms, adapted from Molecular Depot’s original conditions:

    Product Use & Eligibility
    Products are for in vitro research use only (RUO). They are not intended for human or animal use, diagnosis, therapy, resale to consumers, or residential delivery. Sales are limited to verified business addresses.

    Payment Terms
    All purchases are prepaid and non-refundable once confirmed. Pricing is in USD and subject to change without notice.

    Purchase Orders
    Confirmed orders are final and may not be canceled or refunded unless authorized in writing.

    Limitation of Liability
    Blue Tiger Scientific and Molecular Depot LLC are not responsible for any damages resulting from product use or misuse.

    Waiver of Claims
    By ordering, you waive all claims arising from use of Molecular Depot products.

    Shipping & Handling
    Shipping is calculated at checkout. A minimum 27% handling fee applies to each order.

    Delivery Estimates All delivery timelines are estimates and not guaranteed. FedEx service levels are subject to operational delays, weather disruptions, and regional restrictions.

    FedEx Pickup Cutoff Orders submitted after the daily FedEx pickup window may not ship until the next available pickup day.

    Shipping Exceptions FedEx may impose restrictions or delays due to package size, weight, destination, or service availability. Blue Tiger Scientific is not liable for delays beyond our control.

    Weekend & Holiday Handling Orders placed on weekends or holidays will be processed on the next business day.

    Returns & Refunds
    Returns must be requested within 30 days through Blue Tiger Scientific. Refunds are only issued for shipping errors or verified defects, and processed within 45 business days if approved. Customers are responsible for return shipping costs unless otherwise stated. Refunds will exclude original shipping fees paid at checkout.

    Warranty Disclaimer
    All products are provided "as-is" with no warranties. Warranty issues are handled by the manufacturer.

    Safety Guidelines
    Always consult the product’s SDS. Products must not be ingested, inhaled, or come into contact with skin or eyes unless specified.

    Legal Use Compliance
    Products must not be used in violation of any law—local, state, federal, or international.

    Accuracy of Orders
    Customers are responsible for verifying all order details before submission.

    Changes or Cancellations
    All changes must be in writing and approved. Cancellations may result in fees for materials, labor, or third-party costs.

    Quality System (MD Levels)
    Molecular Depot’s MD-Quality System includes:

    MD 1000: Non-regulated use, no change notification

    MD 2000: Non-regulated use, limited change notification

    MD 3000: Regulated use, enhanced quality standards

    Delivery & Claims
    Orders may ship in parts. Claims for shortages or defects must be submitted within 2 days of receipt. Delivery dates are estimates only.

    Extended Payment Terms
    Payment is due within 30 days unless agreed otherwise. A 5% weekly penalty applies to late payments. Blue Tiger Scientific reserves discretion on payment application.

    Retention of Title
    Ownership remains with Blue Tiger Scientific or Molecular Depot LLC until payment is complete. Goods must be stored separately and labeled until paid in full.

    Intellectual Property
    No rights to manufacturing processes or IP are transferred. Blue Tiger Scientific is not liable for IP-related claims.

    Force Majeure
    Neither party is liable for delays or failures caused by uncontrollable events (e.g., weather, regulations, supply disruptions).

    Manufacturing Access
    Product purchase does not grant access to proprietary manufacturing documents or methods.

    Resale Prohibition
    Products cannot be resold without written approval from Molecular Depot LLC. Blue Tiger Scientific enforces this restriction.

    Governing Law
    Terms are governed by California and U.S. law. All disputes fall under U.S. jurisdiction.

Product Resources:

Manual Manual
Brochure Brochure

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

Questions about a product? Ask us here.

email us here: info@bluetigerscientific.com or live chat

Customer Reviews

Be the first to write a review
0%
(0)
0%
(0)
0%
(0)
0%
(0)
0%
(0)