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Caspase-1, Human, Recombinant, E. coli Proteins Molecular Depot
Caspase-1, Human, Recombinant, E. coli Proteins Molecular Depot

Caspase-1, Human, Recombinant, E. coli

$2,395.00

    Catalog Number: B2018846 (3000 U)

    Caspase-1, also known as interleukin-1 converting enzyme (ICE), is a crucial enzyme in the human immune system involved in the inflammatory response. It processes pro-inflammatory cytokines into active forms. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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    Email: info@bluetigerscientific.com

    Text/SMS: (833) 928-4437 Mon–Fri, (8 am – 8 pm PST)

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What's Included

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VR Headset

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2 Touch Controllers

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Charging Cable

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Power Adapter

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Caspase-1, Human, Recombinant, E. coli

Catalog number: B2018846
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 3000 U
Molecular Weight or Concentration: N/A
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: -80°C
Keywords: IL-1β Converting Enzyme, ICE
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References

  • Lu B, Nakamura T, Inouye K, Li J, Tang Y, Lundbäck P, Valdes-Ferrer SI, Olofsson PS, Kalb T, Roth J, Zou Y, Erlandsson-Harris H, Yang H, Ting JP, Wang H, Andersson U, Antoine DJ, Chavan SS, Hotamisligil GS, Tracey KJ. Novel role of PKR in inflammasome activation and HMGB1 release Nature. 2012 Aug 30;488(7413):670-4.
  • Mattiuz G, Nicolò S, Antonelli A, Giani T, Baccani I, Cannatelli A, Clemente AM, Castronovo G, Tanturli M, Cozzolino F, Rossolini GM, Torcia MG. mcr-1 Gene Expression Modulates the Inflammatory Response of Human Macrophages to Escherichia coli Infect Immun. 2020 Jul 21;88(8):e00018-20.
  • Bibo-Verdugo B, Joglekar I, Karadi Giridhar MN, Ramirez ML, Snipas SJ, Clark AC, Poreba M, Salvesen GS. Resurrection of an ancient inflammatory locus reveals switch to caspase-1 specificity on a caspase-4 scaffold J Biol Chem. 2022 Jun;298(6):101931.
  • Verma V, Kumar P, Gupta S, Yadav S, Dhanda RS, Thorlacius H, Yadav M. α-Hemolysin of uropathogenic E. coli regulates NLRP3 inflammasome activation and mitochondrial dysfunction in THP-1 macrophages Sci Rep. 2020 Jul 28;10(1):12653.
  • Zhang S, Ma L, Song F, Wang D, Shi K, Li Y, Zeng J, Wang Y. Pyroptosis of Macrophages Induced by Clostridium perfringens Beta-1 Toxin Toxins (Basel). 2023 May 29;15(6):366.
  • Arlehamn CS, Evans TJ. Pseudomonas aeruginosa pilin activates the inflammasome Cell Microbiol. 2011 Mar;13(3):388-401.
  • Park JA, Kim KW, Kim SI, Lee SK. Caspase 3 specifically cleaves p21WAF1/CIP1 in the earlier stage of apoptosis in SK-HEP-1 human hepatoma cells Eur J Biochem. 1998 Oct 1;257(1):242-8.
  • Reis MI, do Vale A, Pereira PJ, Azevedo JE, Dos Santos NM. Caspase-1 and IL-1β processing in a teleost fish PLoS One. 2012;7(11):e50450.
  • Hong J, Bae S, Jhun H, Lee S, Choi J, Kang T, Kwak A, Hong K, Kim E, Jo S, Kim S. Identification of constitutively active interleukin 33 (IL-33) splice variant J Biol Chem. 2011 Jun 3;286(22):20078-86.

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    Blue Tiger Scientific is an independent third-party distributor of select products manufactured by Molecular Depot LLC. By purchasing from bluetigerscientific.com, you (“the Customer”) agree to the following terms, adapted from Molecular Depot’s original conditions:

    Product Use & Eligibility
    Products are for in vitro research use only (RUO). They are not intended for human or animal use, diagnosis, therapy, resale to consumers, or residential delivery. Sales are limited to verified business addresses.

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    All purchases are prepaid and non-refundable once confirmed. Pricing is in USD and subject to change without notice.

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    Blue Tiger Scientific and Molecular Depot LLC are not responsible for any damages resulting from product use or misuse.

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    MD 1000: Non-regulated use, no change notification

    MD 2000: Non-regulated use, limited change notification

    MD 3000: Regulated use, enhanced quality standards

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Product Resources:

Manual Manual
Brochure Brochure

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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