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Candidalysin (Highly Pure) Peptides Molecular Depot
Candidalysin (Highly Pure) Peptides Molecular Depot
Candidalysin (Highly Pure) Peptides Molecular Depot
Candidalysin (Highly Pure) Peptides Molecular Depot
Candidalysin (Highly Pure) Peptides Molecular Depot
Candidalysin (Highly Pure) Peptides Molecular Depot

Candidalysin (Highly Pure)

$582.00

    Catalog Number: MDP0845 (0.1 mg)

    Products are for in vitro research use only (RUO).

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VR Headset

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2 Touch Controllers

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Charging Cable

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Power Adapter

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Candidalysin (Highly Pure)

Catalog # MDP0845
Name Ser-Ile-Ile-Gly-Ile-Ile-Met-Gly-Ile-Leu-Gly-Asn-Ile-Pro-Gln-Val-Ile-Gln-Ile-Ile-Met-Ser-Ile-Val-Lys-Ala-Phe-Lys-Gly-Asn-Lys
Synonyms Candidalysin
Molecular Formula C₁₅₃H₂₆₆N₃₈O₃₈S₂
Molecular Mass 3310.1 g/mol
Storage −20°C

Candidalysin is a cytolytic peptide toxin secreted by Candida albicans during hyphal formation. It plays a central role in fungal virulence by disrupting epithelial membranes, triggering necrotic cell death, and activating host immune responses. This 31-residue peptide, encoded by the ECE1 gene, is the first fungal peptide toxin identified to directly damage host tissues and stimulate inflammation via the epidermal growth factor receptor (EGFR) pathway.

Researchers use Candidalysin to study mucosal immunity, inflammasome activation, epithelial stress responses, and fungal pathogenesis. It has been implicated in oral carcinogenesis, alcohol-associated liver disease, and systemic Candida infections. Candidalysin also promotes neutrophil recruitment and NLRP3 inflammasome activation, making it a valuable tool for dissecting host-pathogen interactions and immune signaling cascades.

This product is supplied as a highly pure synthetic peptide and is ideal for in vitro assays, epithelial damage models, and immunological studies. It is intended for Research Use Only (RUO) and not for diagnostic or therapeutic applications.

Key Features:

  • 31-residue fungal peptide toxin derived from Candida albicans
  • Validated for use in epithelial damage and immune activation studies
  • Molecular Mass: 3310.1 g/mol; Storage: −20°C
  • RUO designation: not for clinical or therapeutic applications

Indication for Use:
This product is for Research Use Only (RUO). It is not intended for human or animal use, diagnostic procedures, or therapeutic applications.

Safety:
Users must review the Safety Data Sheet (MSDS) prior to handling. Avoid ingestion, inhalation, or contact with eyes, skin, or clothing.

References:
1: Ho J et al. Candida albicans and candidalysin in inflammatory disorders and cancer Immunology. 2021 Jan;162(1):11-16.
2: Chu H et al. Candidalysin promotes alcohol-associated liver disease J Hepatol. 2020 Mar;72(3):391-400.
3: Naglik JR et al. Candidalysin: discovery and function Curr Opin Microbiol. 2019 Dec;52:100-109.
4: Moyes DL et al. Candidalysin is critical for mucosal infection Nature. 2016 Apr 7;532(7597):64-8.
5: Blagojevic M et al. Candidalysin triggers epithelial necrosis Cell Microbiol. 2021 Oct;23(10):e13371.
6: Engku Nasrullah Satiman EAF et al. ECE1 gene in oral carcinogenesis J Oral Pathol Med. 2020 Oct;49(9):835-841.
7: Ho J et al. Candidalysin activates EGFR signaling Nat Commun. 2019 May 24;10(1):2297.
8: Mogavero S et al. Invasion pocket delivery of candidalysin Cell Microbiol. 2021 Oct;23(10):e13378.
9: Swidergall M et al. Candidalysin required for neutrophil recruitment J Infect Dis. 2019 Sep 26;220(9):1477-1488.
10: Rogiers O et al. Candidalysin activates NLRP3 inflammasome mBio. 2019 Jan 8;10(1):e02221-18.

    Terms & Conditions

    Blue Tiger Scientific is an independent third-party distributor of select products manufactured by Molecular Depot LLC. By purchasing from bluetigerscientific.com, you (“the Customer”) agree to the following terms, adapted from Molecular Depot’s original conditions:

    Product Use & Eligibility
    Products are for in vitro research use only (RUO). They are not intended for human or animal use, diagnosis, therapy, resale to consumers, or residential delivery. Sales are limited to verified business addresses.

    Payment Terms
    All purchases are prepaid and non-refundable once confirmed. Pricing is in USD and subject to change without notice.

    Purchase Orders
    Confirmed orders are final and may not be canceled or refunded unless authorized in writing.

    Limitation of Liability
    Blue Tiger Scientific and Molecular Depot LLC are not responsible for any damages resulting from product use or misuse.

    Waiver of Claims
    By ordering, you waive all claims arising from use of Molecular Depot products.

    Shipping & Handling
    Shipping is calculated at checkout. A minimum 27% handling fee applies to each order.

    Delivery Estimates All delivery timelines are estimates and not guaranteed. FedEx service levels are subject to operational delays, weather disruptions, and regional restrictions.

    FedEx Pickup Cutoff Orders submitted after the daily FedEx pickup window may not ship until the next available pickup day.

    Shipping Exceptions FedEx may impose restrictions or delays due to package size, weight, destination, or service availability. Blue Tiger Scientific is not liable for delays beyond our control.

    Weekend & Holiday Handling Orders placed on weekends or holidays will be processed on the next business day.

    Returns & Refunds
    Returns must be requested within 30 days through Blue Tiger Scientific. Refunds are only issued for shipping errors or verified defects, and processed within 45 business days if approved. Customers are responsible for return shipping costs unless otherwise stated. Refunds will exclude original shipping fees paid at checkout.

    Warranty Disclaimer
    All products are provided "as-is" with no warranties. Warranty issues are handled by the manufacturer.

    Safety Guidelines
    Always consult the product’s SDS. Products must not be ingested, inhaled, or come into contact with skin or eyes unless specified.

    Legal Use Compliance
    Products must not be used in violation of any law—local, state, federal, or international.

    Accuracy of Orders
    Customers are responsible for verifying all order details before submission.

    Changes or Cancellations
    All changes must be in writing and approved. Cancellations may result in fees for materials, labor, or third-party costs.

    Quality System (MD Levels)
    Molecular Depot’s MD-Quality System includes:

    MD 1000: Non-regulated use, no change notification

    MD 2000: Non-regulated use, limited change notification

    MD 3000: Regulated use, enhanced quality standards

    Delivery & Claims
    Orders may ship in parts. Claims for shortages or defects must be submitted within 2 days of receipt. Delivery dates are estimates only.

    Extended Payment Terms
    Payment is due within 30 days unless agreed otherwise. A 5% weekly penalty applies to late payments. Blue Tiger Scientific reserves discretion on payment application.

    Retention of Title
    Ownership remains with Blue Tiger Scientific or Molecular Depot LLC until payment is complete. Goods must be stored separately and labeled until paid in full.

    Intellectual Property
    No rights to manufacturing processes or IP are transferred. Blue Tiger Scientific is not liable for IP-related claims.

    Force Majeure
    Neither party is liable for delays or failures caused by uncontrollable events (e.g., weather, regulations, supply disruptions).

    Manufacturing Access
    Product purchase does not grant access to proprietary manufacturing documents or methods.

    Resale Prohibition
    Products cannot be resold without written approval from Molecular Depot LLC. Blue Tiger Scientific enforces this restriction.

    Governing Law
    Terms are governed by California and U.S. law. All disputes fall under U.S. jurisdiction.

Product Resources:

Manual Manual
Brochure Brochure

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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