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Xanthine Oxidase Grade II (Lyophilized Powder) Proteins Molecular Depot
Xanthine Oxidase Grade II (Lyophilized Powder) Proteins Molecular Depot

Xanthine Oxidase Grade II (Lyophilized Powder)

$452.00

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Xanthine Oxidase Grade II (Lyophilized Powder)

Catalog # P2010006
Size 100 U and bulk
Unit Definition 1 µmol uric acid/min at pH 7.5, 25 °C
Molecular Weight 160 kDa
Specific Activity 16 U/mg
Purity Uricase, phosphatase < 0.001%
Storage –20°C; avoid freeze/thaw cycles
Supplied as Brown-red lyophilized powder
Keywords Xanthine oxidase

Xanthine Oxidase Grade II is a purified enzyme preparation supplied as a brown-red lyophilized powder. With a molecular weight of 160 kDa and a specific activity of 16 U/mg, this enzyme catalyzes the oxidation of hypoxanthine to xanthine and subsequently to uric acid. The unit definition corresponds to the amount of enzyme that produces 1 µmol of uric acid per minute at pH 7.5 and 25 °C.

This product is ideal for use in enzymatic assays, oxidative stress studies, and drug screening applications targeting purine metabolism. Its high purity (<0.001% uricase and phosphatase) ensures minimal background interference, making it suitable for sensitive biochemical workflows. The lyophilized format allows for long-term storage at –20°C, and reconstitution should be performed under sterile conditions to preserve activity. Bulk quantities are available for high-throughput or industrial applications.

Key benefits:

  • High-purity enzyme for uric acid generation assays
  • Validated specific activity and molecular weight
  • Lyophilized format for stability and ease of transport
  • Minimal contaminating enzymatic activity (<0.001%)
  • Available in standard and bulk quantities

Indication for Use:
This product is for Research Use Only (RUO). It is not intended for human or animal use, diagnostic procedures, or therapeutic applications.

References:

  • Monika et al. Xanthine oxidase from Acinetobacter calcoaceticus. Protein Expr Purif. 2019;160:36–44.
  • Schuchardt M et al. XO inhibition in cardiovascular disease. Curr Pharm Des. 2017;23(23):3391–3404.
  • Kıbrız İE et al. Pyrrole carboxamide XO inhibitors. Arch Pharm. 2018;351(10):e1800165.
  • Zhang T et al. Imidazole derivatives as XO inhibitors. Eur J Med Chem. 2018;146:668–677.
  • Fukuyama Y et al. Phenylindanes from caffeic acid. Biosci Biotechnol Biochem. 2018;82(10):1825–1828.
  • Zhang TJ et al. Triazole benzonitrile XO inhibitors. Chem Biol Drug Des. 2018;91(2):526–533.
  • Malik N et al. In-silico design of natural XO inhibitors. Curr Drug Metab. 2017;18(6):577–593.
  • Yamaguchi Y et al. XO active site mutation study. J Biochem. 2007;141(4):513–524. PubMed

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Product Resources:

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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