Polystyrene Beads Conjugated to BSA (20 nm) – Research Use Only

Polystyrene Beads Conjugated to BSA (20 nm) are ultra-small 20 nm polystyrene nanoparticles covalently coated with bovine serum albumin (BSA). Supplied as a 1% suspension in 2 mL volume, these BSA-functionalized nanobeads provide a high surface area-to-volume ratio and a stable protein corona, making them an excellent model system for studying nanoparticle–protein and nanoparticle–cell interactions at the nanoscale.

Scientific Overview

20 nm polystyrene beads conjugated with bovine serum albumin (BSA) offer a nanoscale platform with significantly higher surface area compared to micron-sized beads. The BSA coating creates a well-defined protein corona that modulates surface charge, stability, and biological interactions, making these nanoparticles valuable for investigating how size and surface chemistry influence protein adsorption, cellular uptake, and immune recognition.

These 20 nm BSA-conjugated polystyrene beads are suitable for:

• High-resolution studies of protein adsorption and nanoparticle corona formation
• Nanoscale phagocytosis and endocytosis assays in immune cells
• Investigation of size-dependent effects on cellular uptake and trafficking
• Development of nanoparticle-based immunoassays and diagnostic platforms
• Biophysical characterization of nanoparticle–biomolecule interactions using techniques such as microchannel resonators
• Model systems for studying surface adsorption and hopping dynamics in complex media

Usage & Handling Guidance

Store the 1% suspension at 2–8 °C. Do not freeze. Gently vortex or pipette the suspension to ensure uniform resuspension before each use. Sonication may be required for optimal dispersion after prolonged storage.

• Recommended applications: Nanoparticle–protein interaction studies, cellular uptake assays, protein corona research, and nano-scale immunoassays
• Working concentration: Dilute to 0.01–0.1% solids in PBS or appropriate assay buffer as needed
• Stability: Stable when refrigerated; resuspend thoroughly and check for aggregation before use
• Handling: Use in sterile conditions for cell-based experiments; compatible with standard physiological buffers

What You Get

• 2 mL of 20 nm Polystyrene Beads Conjugated to BSA as a 1% suspension
• High surface area nanoparticles with stable BSA coating
• Ready-to-use format for nanoscale biochemical and cellular studies
• Biotechnology-grade product manufactured under controlled quality conditions
• For research use only (RUO)

Why Researchers Choose It

• Ultra-small 20 nm size ideal for high-resolution nanoparticle studies
• Stable BSA conjugation for reproducible protein corona formation
• Excellent model for size-dependent effects in cellular uptake and protein adsorption
• Versatile platform for nanomedicine, immunology, and biophysical research
• High-quality 1% suspension suitable for sensitive experimental applications

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