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Phospho-Ship2 (Tyr1135) Rabbit Antibody PE Conjugate Antibodies Molecular Depot
Phospho-Ship2 (Tyr1135) Rabbit Antibody PE Conjugate Antibodies Molecular Depot
Phospho-Ship2 (Tyr1135) Rabbit Antibody PE Conjugate Antibodies Molecular Depot
Phospho-Ship2 (Tyr1135) Rabbit Antibody PE Conjugate Antibodies Molecular Depot

Phospho-Ship2 (Tyr1135) Rabbit Antibody PE Conjugate

$1,395.00

    Catalog Number: B2018358 (10 Tests)

    The Phospho-Ship2 (Tyr1135) Rabbit Antibody PE Conjugate is a specific antibody used in research to detect and measure the phosphorylation of the Ship2 protein at the tyrosine 1135 residue. It is conjugated with the fluorescent dye PE for easy detection of the phosphorylated Ship2 protein in cells or tissues using flow cytometry or fluorescence microscopy techniques. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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    Email: info@bluetigerscientific.com

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What's Included

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VR Headset

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2 Touch Controllers

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Charging Cable

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Power Adapter

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Glasses Spacer

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Phospho-Ship2 (Tyr1135) Rabbit Antibody PE Conjugate

Catalog number: B2018358
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 Tests
Molecular Weight or Concentration: N/A
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: 2-8 °C
Keywords: Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2, Inositol polyphosphate phosphatase-like protein 1, INPPL-1, Protein 51C, SH2 domain-containing inositol 5′-phosphatase 2
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References

  • Fu CH, Lin RJ, Yu J, Chang WW, Liao GS, Chang WY, Tseng LM, Tsai YF, Yu JC, Yu AL. A novel oncogenic role of inositol phosphatase SHIP2 in ER-negative breast cancer stem cells: involvement of JNK/vimentin activation Stem Cells. 2014 Aug;32(8):2048-60.
  • Elong Edimo W, Derua R, Janssens V, Nakamura T, Vanderwinden JM, Waelkens E, Erneux C. Evidence of SHIP2 Ser132 phosphorylation, its nuclear localization and stability Biochem J. 2011 Nov 1;439(3):391-401.
  • Artemenko Y, Gagnon A, Sorisky A. Catalytically inactive SHIP2 inhibits proliferation by attenuating PDGF signaling in 3T3-L1 preadipocytes J Cell Physiol. 2009 Jan;218(1):228-36.
  • Jesudason CD, Mason ER, Chu S, Oblak AL, Javens-Wolfe J, Moussaif M, Durst G, Hipskind P, Beck DE, Dong J, Amarasinghe O, Zhang ZY, Hamdani AK, Singhal K, Mesecar AD, Souza S, Jacobson M, Salvo JD, Soni DM, Kandasamy M, Masters AR, Quinney SK, Doolen S, Huhe H, Rizzo SJS, Lamb BT, Palkowitz AD, Richardson TI. SHIP1 therapeutic target enablement: Identification and evaluation of inhibitors for the treatment of late-onset Alzheimer’s disease Alzheimers Dement (N Y). 2023 Nov 17;9(4):e12429.
  • Zwaenepoel K, Goris J, Erneux C, Parker PJ, Janssens V. Protein phosphatase 2A PR130/B”alpha1 subunit binds to the SH2 domain-containing inositol polyphosphate 5-phosphatase 2 and prevents epidermal growth factor (EGF)-induced EGF receptor degradation sustaining EGF-mediated signaling FASEB J. 2010 Feb;24(2):538-47.
  • Siddall HK, Warrell CE, Yellon DM, Mocanu MM. Ischemia-reperfusion injury and cardioprotection: investigating PTEN, the phosphatase that negatively regulates PI3K, using a congenital model of PTEN haploinsufficiency Basic Res Cardiol. 2008 Nov;103(6):560-8.
  • Vandeput F, Backers K, Villeret V, Pesesse X, Erneux C. The influence of anionic lipids on SHIP2 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase activity Cell Signal. 2006 Dec;18(12):2193-9.
  • Kabuyama Y, Nakatsu N, Homma Y, Fukui Y. Purification and characterization of the phosphatidylinositol-3,4,5-trisphosphate phosphatase in bovine thymus Eur J Biochem. 1996 Jun 1;238(2):350-6.
  • Wisniewski D, Strife A, Swendeman S, Erdjument-Bromage H, Geromanos S, Kavanaugh WM, Tempst P, Clarkson B. A novel SH2-containing phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase (SHIP2) is constitutively tyrosine phosphorylated and associated with src homologous and collagen gene (SHC) in chronic myelogenous leukemia progenitor cells Blood. 1999 Apr 15;93(8):2707-20.

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    Blue Tiger Scientific is an independent third-party distributor of select products manufactured by Molecular Depot LLC. By purchasing from bluetigerscientific.com, you (“the Customer”) agree to the following terms, adapted from Molecular Depot’s original conditions:

    Product Use & Eligibility
    Products are for in vitro research use only (RUO). They are not intended for human or animal use, diagnosis, therapy, resale to consumers, or residential delivery. Sales are limited to verified business addresses.

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    All purchases are prepaid and non-refundable once confirmed. Pricing is in USD and subject to change without notice.

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Product Resources:

Manual Manual
Brochure Brochure

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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