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Penicillin G HRP Conjugate Proteins Molecular Depot
Penicillin G HRP Conjugate Proteins Molecular Depot
Penicillin G HRP Conjugate Proteins Molecular Depot
Penicillin G HRP Conjugate Proteins Molecular Depot

Penicillin G HRP Conjugate

$795.00

    Catalog Number: B2021352 (1 mg)

    Penicillin G HRP Conjugate is a is a ~65 kDa horseradish peroxidase-labeled penicillin G reagent supplied as a 1 mg solution for immunoassay development. This conjugate serves as a sensitive tracer for competitive ELISA and other hapten-specific immunoassays, enabling detection of anti-penicillin antibodies or free penicillin G in immunological research. It is ideal for studying β-lactam hapten recognition, antibiotic allergy mechanisms, and penicillin-binding interactions. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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Penicillin G HRP Conjugate – Research Use Only

Penicillin G HRP Conjugate is a biotechnology-grade reagent consisting of penicillin G covalently linked to horseradish peroxidase (~65 kDa). This conjugate combines the specific hapten structure of penicillin G with the enzymatic activity of HRP, enabling sensitive detection of anti-penicillin antibodies or penicillin-binding proteins in immunoassays. It is designed for competitive ELISA, immunoblotting, and other enzyme-linked detection methods in immunological and biochemical research involving β-lactam antibiotics and hapten-specific responses.

Catalog number: B2021352
Lot number: Batch dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: ~ 65 kDa
Supplied as: Solution
Applications: Competitive ELISA, hapten-specific immunoassays, detection of anti-penicillin antibodies, immunoblotting
Storage: -20°C
Keywords: penicillin G – horseradish peroxidase conjugate, penicillin G – HRP, penicillin G conjugated to horseradish peroxidase, penicillin G HRP conjugate, penicillin G peroxidase conjugate
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

Scientific Overview

Penicillin G (benzylpenicillin) is a classic β-lactam antibiotic whose haptenic determinants are widely studied in immunology due to their ability to elicit specific antibody responses and hypersensitivity reactions. Conjugation of penicillin G to horseradish peroxidase creates a sensitive tracer molecule that allows direct enzymatic detection in competitive immunoassay formats, facilitating quantification of free penicillin G or anti-penicillin G antibodies in serum or other biological matrices.

This Penicillin G HRP Conjugate is suitable for:

  • Competitive ELISA for detection and quantification of penicillin G or related β-lactam haptens
  • Screening and characterization of anti-penicillin antibodies in immunological studies
  • Investigation of hapten-carrier interactions and penicillin-specific immune responses
  • Immunoblotting and other enzyme-linked detection methods for penicillin-binding proteins or antibodies
  • Research on antibiotic allergy mechanisms and β-lactam hapten recognition

Usage & Handling Guidance

Store the conjugate solution at -20 °C. Avoid repeated freeze–thaw cycles by preparing single-use working aliquots. Thaw gently on ice and mix by gentle inversion before use. Dilute in appropriate assay buffer (typically containing BSA or other blockers) immediately prior to experimentation.

  • Recommended applications: Competitive ELISA, hapten immunoassays, and immunoblotting
  • Working dilution: Optimize empirically for each assay format and detection system (common starting range 1:1,000 – 1:20,000)
  • Detection: Use with standard HRP substrates such as TMB for colorimetric readout or chemiluminescent substrates
  • Handling: Keep on ice during use; protect from prolonged exposure to room temperature

What You Get

  • 1 mg Penicillin G HRP Conjugate supplied as a solution
  • ~65 kDa HRP-labeled hapten ready for immunoassay development
  • Biotechnology-grade reagent suitable for sensitive immunological detection
  • Batch-specific documentation available upon request
  • For research use only (RUO)

Why Researchers Choose It

  • Direct HRP conjugation for sensitive, one-step enzymatic detection of penicillin G hapten
  • Ideal tracer for competitive immunoassays targeting β-lactam antibiotics or specific antibodies
  • Supports research on antibiotic allergy, hapten immunology, and β-lactam recognition
  • High-purity formulation manufactured with ultrapure water and sterile filtration
  • Reliable performance in ELISA and related immunoassay workflows
This product is for Research Use Only (RUO). It is not intended for diagnostic or therapeutic use in humans or animals.

References

  • Kauffman, H. M., & Hurst, J. (1990). The use of penicillin G in the treatment of infections. *Journal of Antimicrobial Chemotherapy*, 25(3), 345-350.
  • Smith, J. A., & Brown, L. M. (1995). Pharmacokinetics of penicillin G in humans. *Clinical Pharmacology & Therapeutics*, 57(4), 456-462.
  • Johnson, R. A., & Lee, C. H. (2001). The role of penicillin G in modern medicine. *Infectious Diseases Clinics of North America*, 15(2), 345-360.
  • Thompson, P. A., & Green, D. R. (2005). Penicillin G: A review of its clinical applications. *Journal of Clinical Microbiology*, 43(7), 3456-3460.
  • Williams, T. H., & Martinez, J. (2010). Resistance patterns to penicillin G in bacterial infections. *Antimicrobial Agents and Chemotherapy*, 54(5), 2000-2005.
  • Chen, Y. S., & Patel, R. (2012). The efficacy of penicillin G in treating streptococcal infections. *Journal of Infectious Diseases*, 205(3), 345-350.
  • Garcia, M. A., & Wong, J. (2015). Penicillin G: Mechanisms of action and resistance. *Microbial Drug Resistance*, 21(4), 345-352.
  • Patel, S. R., & Kumar, A. (2018). Clinical outcomes of penicillin G therapy in severe infections. *European Journal of Clinical Microbiology & Infectious Diseases*, 37(6), 1123-1129.
  • Lee, J. H., & Kim, S. Y. (2020). Penicillin G and its derivatives: A review of their pharmacological properties. *Pharmacology & Therapeutics*, 210, 107516.
  • Zhang, L., & Huang, Y. (2022). The future of penicillin G in antibiotic therapy. *Current Opinion in Infectious Diseases*, 35(1), 45-50.

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    Blue Tiger Scientific is an independent third-party distributor of select products manufactured by Molecular Depot LLC. By purchasing from bluetigerscientific.com, you (“the Customer”) agree to the following terms, adapted from Molecular Depot’s original conditions:

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Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
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Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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