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Human NADPH Cytochrome P450 Reductase Proteins Molecular Depot
Human NADPH Cytochrome P450 Reductase Proteins Molecular Depot
Human NADPH Cytochrome P450 Reductase Proteins Molecular Depot
Human NADPH Cytochrome P450 Reductase Proteins Molecular Depot

Human NADPH Cytochrome P450 Reductase

$2,195.00

    Catalog Number: B2016764 (50 µg)

    Human NADPH Cytochrome P450 Reductase is a high quality enzyme that plays a crucial role in the function of cytochrome P450 enzymes. It is involved in the transfer of electrons to cytochrome P450 enzymes, which are responsible for metabolizing various compounds in the body, including toxins, and hormones. This enzyme is essential for the proper functioning of cytochrome P450 enzymes and is important for drug metabolism and detoxification processes in the body. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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What's Included

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VR Headset

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2 Touch Controllers

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Charging Cable

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Power Adapter

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Human NADPH Cytochrome P450 Reductase

Catalog number: B2016764
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 µg
Molecular Weight or Concentration: 76.4 kDa
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: -80°C
Keywords: NADPH-dependent Thioredoxin Reductase, TrxR1, Txnrd1
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References

  • Park HG, Lim YR, Han S, Jeong D, Kim D. Enhanced Purification of Recombinant Rat NADPH-P450 Reductase by Using a Hexahistidine-Tag J Microbiol Biotechnol. 2017 May 28;27(5):983-989.
  • Mishin V, Heck DE, Laskin DL, Laskin JD. Human recombinant cytochrome P450 enzymes display distinct hydrogen peroxide generating activities during substrate independent NADPH oxidase reactions Toxicol Sci. 2014 Oct;141(2):344-52.
  • Burris-Hiday SD, Scott EE. Allosteric modulation of cytochrome P450 enzymes by the NADPH cytochrome P450 reductase FMN-containing domain J Biol Chem. 2023 Sep;299(9):105112.
  • Khan MF, Murphy CD. Nitroreduction of flutamide by Cunninghamella elegans NADPH: Cytochrome P450 reductase Biochem Biophys Rep. 2022 Jan 17;29:101209.
  • Szilagyi JT, Fussell KC, Wang Y, Jan YH, Mishin V, Richardson JR, Heck DE, Yang S, Aleksunes LM, Laskin DL, Laskin JD. Quinone and nitrofurantoin redox cycling by recombinant cytochrome b5 reductase Toxicol Appl Pharmacol. 2018 Nov 15;359:102-107.
  • Shet MS, Fisher CW, Holmans PL, Estabrook RW. Human cytochrome P450 3A4: enzymatic properties of a purified recombinant fusion protein containing NADPH-P450_reductase Proc Natl Acad Sci U S A. 1993 Dec 15;90(24):11748-52.
  • Park HG, Lim YR, Eun CY, Han S, Han JS, Cho KS, Chun YJ, Kim D. Candida albicans NADPH-P450_reductase: expression, purification, and characterization of recombinant protein Biochem Biophys Res Commun. 2010 May 28;396(2):534-8.
  • Shaw PM, Hosea NA, Thompson DV, Lenius JM, Guengerich FP. Reconstitution premixes for assays using purified recombinant human cytochrome P450, NADPH-cytochrome P450_reductase, and cytochrome b5 Arch Biochem Biophys. 1997 Dec 1;348(1):107-15.
  • Ramji S, Lee C, Inaba T, Patterson AV, Riddick DS. Human NADPH-cytochrome p450 reductase overexpression does not enhance the aerobic cytotoxicity of doxorubicin in human breast cancer cell lines Cancer Res. 2003 Oct 15;63(20):6914-9.

    Terms & Conditions

    Blue Tiger Scientific is an independent third-party distributor of select products manufactured by Molecular Depot LLC. By purchasing from bluetigerscientific.com, you (“the Customer”) agree to the following terms, adapted from Molecular Depot’s original conditions:

    Product Use & Eligibility
    Products are for in vitro research use only (RUO). They are not intended for human or animal use, diagnosis, therapy, resale to consumers, or residential delivery. Sales are limited to verified business addresses.

    Payment Terms
    All purchases are prepaid and non-refundable once confirmed. Pricing is in USD and subject to change without notice.

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    Blue Tiger Scientific and Molecular Depot LLC are not responsible for any damages resulting from product use or misuse.

    Waiver of Claims
    By ordering, you waive all claims arising from use of Molecular Depot products.

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    Quality System (MD Levels)
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    MD 1000: Non-regulated use, no change notification

    MD 2000: Non-regulated use, limited change notification

    MD 3000: Regulated use, enhanced quality standards

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Product Resources:

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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