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Human CIAO1 Protein Proteins Molecular Depot
Human CIAO1 Protein Proteins Molecular Depot
Human CIAO1 Protein Proteins Molecular Depot
Human CIAO1 Protein Proteins Molecular Depot

Human CIAO1 Protein

$795.00

    Catalog Number: B2011954 (100 µg)

    Human CIAO1 Protein is a high quality recombinant human CIAO1 protein His tagged and expressed in E.coli. This product has been used as fluorescent dye commonly used as a tracer agent. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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What's Included

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VR Headset

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2 Touch Controllers

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Charging Cable

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Power Adapter

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Glasses Spacer

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Human CIAO1 Protein

Catalog number: B2011954
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 µg
Molecular Weight or Concentration: 1 mg/mL
Supplied as: Solution
Applications: fluorescent dye commonly used as a tracer agent
Storage: -20 °C
Keywords: Probable cytosolic iron-sulfur protein assembly protein CIAO1 protein, CIA1 protein, WDR39 protein, CIAO1, CIAO 1, CIAO-1, CIAO 1 protein, CIAO-1 protein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References

  • Nan H, Kim YJ, Tsuchiya M, Fukao T, Hara N, Hagihara A, Nishioka K, Hattori N, Hara N, Ikeuchi T, Ohtsuka T, Takiyama Y. A Novel Heterozygous Missense Variant in the CIAO1 Gene in a Family with Alzheimer’s Disease: The Val67Ile Variant Promotes the Interaction of CIAO1 and Amyloid-β Protein Precursor J Alzheimers Dis. 2021;84(2):599-605.
  • Maione V, Cantini F, Severi M, Banci L. Investigating the role of the human CIA2A-CIAO1 complex in the maturation of aconitase Biochim Biophys Acta Gen Subj. 2018 Sep;1862(9):1980-1987.
  • Maione V, Grifagni D, Torricella F, Cantini F, Banci L. CIAO3 protein forms a stable ternary complex with two key players of the human cytosolic iron-sulfur cluster assembly machinery J Biol Inorg Chem. 2020 May;25(3):501-508.
  • Kassube SA, Thomä NH. Structural insights into Fe-S protein biogenesis by the CIA targeting complex Nat Struct Mol Biol. 2020 Aug;27(8):735-742.
  • Moiseeva TN, Gamper AM, Hood BL, Conrads TP, Bakkenist CJ. Human DNA polymerase ε is phosphorylated at serine-1940 after DNA damage and interacts with the iron-sulfur complex chaperones CIAO1 and MMS19 DNA Repair (Amst). 2016 Jul;43:9-17.
  • Seki M, Takeda Y, Iwai K, Tanaka K. IOP1 protein is an external component of the human cytosolic iron-sulfur cluster assembly (CIA) machinery and functions in the MMS19 protein-dependent CIA pathway J Biol Chem. 2013 Jun 7;288(23):16680-16689.
  • Srinivasan V, Netz DJ, Webert H, Mascarenhas J, Pierik AJ, Michel H, Lill R. Structure of the yeast WD40 domain protein Cia1, a component acting late in iron-sulfur protein biogenesis Structure. 2007 Oct;15(10):1246-57.
  • Maio N, Rouault TA. Outlining the Complex Pathway of Mammalian Fe-S Cluster Biogenesis Trends Biochem Sci. 2020 May;45(5):411-426.
  • Stehling O, Mascarenhas J, Vashisht AA, Sheftel AD, Niggemeyer B, Rösser R, Pierik AJ, Wohlschlegel JA, Lill R. Human CIA2A-FAM96A and CIA2B-FAM96B integrate iron homeostasis and maturation of different subsets of cytosolic-nuclear iron-sulfur proteins Cell Metab. 2013 Aug 6;18(2):187-98.

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    Products are for in vitro research use only (RUO). They are not intended for human or animal use, diagnosis, therapy, resale to consumers, or residential delivery. Sales are limited to verified business addresses.

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Product Resources:

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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