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Human AKR1C4 Protein (Highly Pure) Proteins Molecular Depot
Human AKR1C4 Protein (Highly Pure) Proteins Molecular Depot
Human AKR1C4 Protein (Highly Pure) Proteins Molecular Depot
Human AKR1C4 Protein (Highly Pure) Proteins Molecular Depot

Human AKR1C4 Protein (Highly Pure)

$795.00

    Catalog Number: B2011566 (100 µg)

    Human AKR1C4 Protein (Highly Pure) is a high quality recombinant human AKR1C4 protein His tagged and expressed in E. coli. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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    Email: info@bluetigerscientific.com

    Text/SMS: (833) 928-4437 Mon–Fri, (8 am – 8 pm PST)

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All products are covered by manufacturer warranty

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What's Included

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VR Headset

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2 Touch Controllers

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Charging Cable

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Power Adapter

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Glasses Spacer

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Human AKR1C4 Protein (Highly Pure)

Catalog number: B2011566
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 µg
Molecular Weight or Concentration: 1 mg/mL
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: AKR1C4 protein (His tag), Purified recombinant AKR1C4 protein, ST2A1 protein, AKRC4 1 protein, ST2A3 protein, AKRC4-1 protein, AKRC4 1, ST2 protein, AKR1C4, HST protein, DHEA-ST protein, AKRC4-1, hSTa protein, DHEAS protein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References

  • Stayrook KR, Rogers PM, Savkur RS, Wang Y, Su C, Varga G, Bu X, Wei T, Nagpal S, Liu XS, Burris TP. Regulation of human 3 alpha-hydroxysteroid dehydrogenase (AKR1C4) expression by the liver X receptor alpha Mol Pharmacol. 2008 Feb;73(2):607-12.
  • Brožič P, Turk S, Rižner TL, Gobec S. Inhibitors of aldo-keto reductases AKR1C1-AKR1C4 Curr Med Chem. 2011;18(17):2554-65.
  • Penning TM, Burczynski ME, Jez JM, Hung CF, Lin HK, Ma H, Moore M, Palackal N, Ratnam K. Human 3alpha-hydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones Biochem J. 2000 Oct 1;351(Pt 1):67-77.
  • Jin Y, Mesaros AC, Blair IA, Penning TM. Stereospecific reduction of 5β-reduced steroids by human ketosteroid reductases of the AKR (aldo-keto reductase) superfamily: role of AKR1C1-AKR1C4 in the metabolism of testosterone and progesterone via the 5β-reductase pathway Biochem J. 2011 Jul 1;437(1):53-61.
  • Lee WH, Lukacik P, Guo K, Ugochukwu E, Kavanagh KL, Marsden B, Oppermann U. Structure-activity relationships of human AKR-type oxidoreductases involved in bile acid synthesis: AKR1D1 and AKR1C4 Mol Cell Endocrinol. 2009 Mar 25;301(1-2):199-204.
  • Penning TM, Chen M, Jin Y. Promiscuity and diversity in 3-ketosteroid reductases J Steroid Biochem Mol Biol. 2015 Jul;151:93-101.
  • Ohta T, Ishikura S, Shintani S, Usami N, Hara A. Kinetic alteration of a human dihydrodiol/3alpha-hydroxysteroid dehydrogenase isoenzyme, AKR1C4, by replacement of histidine-216 with tyrosine or phenylalanine Biochem J. 2000 Dec 15;352 Pt 3(Pt 3):685-91.
  • Stancil SL, Nolte W, Pearce RE, Staggs VS, Leeder JS. The Impact of Age and Genetics on Naltrexone Biotransformation Drug Metab Dispos. 2022 Feb;50(2):168-173.
  • Miller WL. The syndrome of 17,20 lyase deficiency J Clin Endocrinol Metab. 2012 Jan;97(1):59-67.

    Terms & Conditions

    Blue Tiger Scientific is an independent third-party distributor of select products manufactured by Molecular Depot LLC. By purchasing from bluetigerscientific.com, you (“the Customer”) agree to the following terms, adapted from Molecular Depot’s original conditions:

    Product Use & Eligibility
    Products are for in vitro research use only (RUO). They are not intended for human or animal use, diagnosis, therapy, resale to consumers, or residential delivery. Sales are limited to verified business addresses.

    Payment Terms
    All purchases are prepaid and non-refundable once confirmed. Pricing is in USD and subject to change without notice.

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    Blue Tiger Scientific and Molecular Depot LLC are not responsible for any damages resulting from product use or misuse.

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    Warranty Disclaimer
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    Always consult the product’s SDS. Products must not be ingested, inhaled, or come into contact with skin or eyes unless specified.

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    Quality System (MD Levels)
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    MD 1000: Non-regulated use, no change notification

    MD 2000: Non-regulated use, limited change notification

    MD 3000: Regulated use, enhanced quality standards

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Product Resources:

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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