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Histone H1 (bovine)mTOR/mLST8/Raptor Complex Proteins Molecular Depot
Histone H1 (bovine)mTOR/mLST8/Raptor Complex Proteins Molecular Depot
Histone H1 (bovine)mTOR/mLST8/Raptor Complex Proteins Molecular Depot
Histone H1 (bovine)mTOR/mLST8/Raptor Complex Proteins Molecular Depot

Histone H1 (bovine)mTOR/mLST8/Raptor Complex

$2,195.00

    Catalog Number: B2016844 (10 µg)

    Histone H1 (bovine)mTOR/mLST8/Raptor Complex is a high quality protein that plays a role in the packaging of DNA into chromatin. It helps condense the DNA into a more compact structure within the cell nucleus. mTOR (mechanistic target of rapamycin) is a protein complex that regulates cell growth, proliferation, and survival. It consists of several subunits, including mLST8 and Raptor. mLST8 is a positive regulator of mTOR activity, while Raptor is involved in substrate recognition and binding. The complex you mentioned, Histone H1 (bovine) mTOR/mLST8/Raptor Complex Human Recombinant , likely refers to a complex formed by combining Histone H1 from bovine, mTOR, mLST8, and Raptor from human sources in a recombinant system. This complex may be used in research to study the interactions between histones, mTOR signaling, and chromatin structure. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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Histone H1 (bovine)mTOR/mLST8/Raptor Complex

Catalog number: B2016844
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 µg
Molecular Weight or Concentration: 137 (mTOR), 37 (mLST8), and 150 (Raptor) kDa
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: -80°C
Keywords: mTOR: FKBP12-Rapamycin Complex-associated ProteinFK506-binding Protein 12-Rapamycin Complex-associated Protein 1, Mammalian Target of Rapamycin, Mechanistic Target of Rapamycin, Rapamycin and FKBP12 Target 1, Rapamycin Target Protein 1, Serine/Threonine-protein Kinase mTOR, mLST8: G protein β Subunit-like, Gable, GβL, Target of Rapamycin Complex Subunit LST8, TORC Subunit LST8, Mammalian Lethal with SEC13 Protein 8, Raptor: Regulatory-associated Protein of mTOR, RPTOR, p150 Target of Rapamycin-scaffold Protein, p150 TOR-scaffold Protein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References

  • Cao Y, Hu G, Long X, Li F, Wang J, Sun M, Xie Y, Ge Y, Guo W, Liu J, Fu S. Valine promotes milk synthesis by regulating PKM2 nuclear accumulation and histone H3 acetylation through the TAS1R1-mTOR-DDX39B signaling pathway Int J Biol Macromol. 2024 Jan;254(Pt 3):127786.
  • Qi H, Wang L, Zhang M, Wang Z, Gao X, Li M. Methionine and leucine induce ARID1A degradation to promote mTOR expression and milk synthesis in mammary epithelial cells J Nutr Biochem. 2022 Mar;101:108924.
  • Li Y, Liu J, Cui Y, Cao Y, Xu P, Kan X, Guo W, Fu S. Sodium butyrate attenuates bovine mammary epithelial cell injury by inhibiting the formation of neutrophil extracellular traps Int Immunopharmacol. 2022 Sep;110:109009.
  • Shapiro JS, Chang HC, Tatekoshi Y, Zhao Z, Waxali ZS, Hong BJ, Chen H, Geier JA, Bartom ET, De Jesus A, Nejad FK, Mahmoodzadeh A, Sato T, Ramos-Alonso L, Romero AM, Martinez-Pastor MT, Jiang SC, Sah-Teli SK, Li L, Bentrem D, Lopaschuk G, Ben-Sahra I, O’Halloran TV, Shilatifard A, Puig S, Bergelson J, Koivunen P, Ardehali H. Iron drives anabolic metabolism through active histone demethylation and mTORC1 Nat Cell Biol. 2023 Oct;25(10):1478-1494.
  • de Lima JD, de Paula AGP, Yuasa BS, de Souza Smanioto CC, da Cruz Silva MC, Dos Santos PI, Prado KB, Winter Boldt AB, Braga TT. Genetic and Epigenetic Regulation of the Innate Immune Response to Gout Immunol Invest. 2023 Apr;52(3):364-397.
  • Ni Q, Sun J, Wang Y, Wang Y, Liu J, Ning G, Wang W, Wang Q. mTORC1 is required for epigenetic silencing during β-cell functional maturation Mol Metab. 2022 Oct;64:101559.
  • Pezoa SA, Artinger KB, Niswander LA. GCN5 acetylation is required for craniofacial chondrocyte maturation Dev Biol. 2020 Aug 1;464(1):24-34.
  • Makarević J, Rutz J, Juengel E, Maxeiner S, Tsaur I, Chun FK, Bereiter-Hahn J, Blaheta RA. Influence of the HDAC Inhibitor Valproic Acid on the Growth and Proliferation of Temsirolimus-Resistant Prostate Cancer Cells In Vitro Cancers (Basel). 2019 Apr 19;11(4):566.
  • Andrés M, García-Gomis D, Ponte I, Suau P, Roque A. Histone H1 Post-Translational Modifications: Update and Future Perspectives Int J Mol Sci. 2020 Aug 18;21(16):5941.

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Product Resources:

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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