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Folic Acid BSA Biotinylated (High Purity) Proteins Molecular Depot
Folic Acid BSA Biotinylated (High Purity) Proteins Molecular Depot
Folic Acid BSA Biotinylated (High Purity) Proteins Molecular Depot
Folic Acid BSA Biotinylated (High Purity) Proteins Molecular Depot

Folic Acid BSA Biotinylated (High Purity)

$647.00

    Catalog #: B2010395 (0.5 mg)

    Folic Acid BSA Biotinylated (0.5 mg) consists of a concentrated solution of Biotinylated Bovine Serum Albumin (BSA) conjugated to Folic Acid (known as folate in its anionic form). A carbon spacer arm of 10.0 Å links BSA to the Folic Acid moiety. Each BSA molecule contains several Folic Acid units. This product has been validated in methods that detect folic acid. Dilutions of the provided conjugate can be made Phosphate Buffer Saline. For in vitro research use only. Custom bulk orders of this product are available upon request.

    Products are for in vitro research use only (RUO).

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Folic Acid BSA Biotinylated (High Purity)

Catalog number: B2010395
Lot number: Batch Dependent
Expiration date: Batch Dependent
Purity: > 95%
Concentration: 1 mg/mL
Package Size: 0.5 mg
Molecular Weight: 71 kDa (average)
Storage: -20°C. Avoid repeated freeze/thaw cycles.
Other names: BSA-Folic Acid Biotin, Biotin Folic Acid-BSA, Biotin-BSA conjugated to Folic Acid, Folic Acid Bovine Serum Albumin Biotin Conjugate, Folic Acid [BSA] Biotin, Biotin-BSA-Folate, Folate-BSA-Biotin, BSA conjugated to Folate and Biotin, Folate Biotin Bovine Serum Albumin Conjugate, Folate [BSA] Biotin
Keywords: 5 Methyl THFA; 5 Methyltetrahydrofolate; Folate; Tetrahydrofolate; Tetrahydrofolic acid; THFA, folate-bsa
Buffer: 1X Phosphate Buffer Saline, pH 7.4.

Folic Acid BSA Biotinylated is a high-purity conjugate designed for targeted biochemical and diagnostic applications involving folate recognition, receptor binding, and biotin-mediated capture. This reagent consists of folic acid covalently linked to bovine serum albumin (BSA), with biotin incorporated for affinity-based detection or immobilization. The conjugate is supplied at a concentration of 1 mg/mL in 1X phosphate-buffered saline (pH 7.4), with a typical molecular weight of ~71 kDa and a purity exceeding 95%.

This product is ideal for researchers studying folate metabolism, receptor-mediated endocytosis, drug delivery systems, and vitamin B9 deficiency. The biotinylated format enables seamless integration into streptavidin-based platforms, including ELISA, biosensors, bead-based assays, and surface immobilization protocols. The BSA carrier enhances solubility and stability, while the folic acid moiety retains biological activity for receptor targeting and competitive binding studies.

Folic acid (also known as folate when present in its anionic form) is a water-soluble B vitamin. Its active form, Tetrahydrofolic Acid (THFA), is obtained by an enzymatic reaction in which folic acid is reduced into THFA by the enzyme dihydrofolate reductase. THFA is important in many biosynthetic reactions that include the transfer of single-carbon containing groups and the biosynthesis of purines, thymidine, and certain amino acids. This conjugate supports applications in oncology (e.g., folate receptor-positive tumor targeting), prenatal nutrition research, and neurocognitive studies involving B-vitamin pathways.

Key benefits:

  • Biotinylated folic acid conjugated to BSA for enhanced solubility and stability
  • Compatible with streptavidin-based capture and immobilization platforms
  • Supports folate receptor binding, drug delivery, and metabolic profiling
  • Supplied in PBS buffer (pH 7.4); ready-to-use format
  • ≥95% purity; filtered through 0.22 μm membranes
  • Stable at –20°C; avoid repeated freeze/thaw cycles

Products are for in vitro research use only (RUO).

References

  • Maekawa A, Nakajima H, Kawata T. Folic acid. Nihon Rinsho. 1999 Oct;57(10):2254-60.
  • Naithani M, Saxena V, Mirza AA, Kumari R, Sharma K, Bharadwaj J. Assessment of Folic Acid Supplementation in Pregnant Women by Estimation of Serum Levels of Tetrahydrofolic Acid, Dihydrofolate Reductase, and Homocysteine. Scientifica (Cairo). 2016;2016:1520685.
  • Chen J, Chen X, Yang Z, Tan X, Wang J, Chen Y. Preparation and characterization of folic acid functionalized bioactive glass for targeted delivery and sustained release of methotrexate. J Biomed Mater Res A. 2019 Feb;107(2):319-329.
  • Ai J, Xu Y, Li D, Liu Z, Wang E. Folic acid as delivery vehicles: targeting folate conjugated fluorescent nanoparticles to tumors imaging. Talanta. 2012 Nov 15;101:32-7.
  • Morris MS. The role of B vitamins in preventing and treating cognitive impairment and decline. Adv Nutr. 2012 Nov 1;3(6):801-12.

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Product Resources:

Manual Manual
Brochure Brochure

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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