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DS-TNFR2 M196R Variant (human, recombinant) Proteins Molecular Depot
DS-TNFR2 M196R Variant (human, recombinant) Proteins Molecular Depot

DS-TNFR2 M196R Variant (human, recombinant)

$1,795.00

    Catalog Number: B2017290 (100 µg)

    DS-TNFR2 M196R Variant (human, recombinant) is a modified form of the human Tumor Necrosis Factor Receptor 2 (TNFR2) produced through recombinant DNA technology. The M196R mutation replaces methionine with arginine at position 196, potentially altering the protein’s function, stability, or interactions. This variant is used in research to study protein function and immune responses. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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What's Included

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VR Headset

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2 Touch Controllers

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Charging Cable

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Power Adapter

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Glasses Spacer

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DS-TNFR2 M196R Variant (human, recombinant)

Catalog number: B2017290
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 µg
Molecular Weight or Concentration: 27.7 kDa
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: −80°C
Keywords: CD120b, TNFR2, DS-TNFR2(Δ7,8), TNFRSF1B, Tumor Necrosis Factor Receptor 2, Tumor Necrosis Factor Receptor Superfamily Member 1B,
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References

  • Horiuchi T, Kiyohara C, Tsukamoto H, Sawabe T, Furugo I, Yoshizawa S, Ueda A, Tada Y, Nakamura T, Kimoto Y, Mitoma H, Harashima S, Yoshizawa S, Shimoda T, Okamura S, Nagasawa K, Harada M. A functional M196R polymorphism of tumour necrosis factor receptor type 2 is associated with systemic lupus erythematosus: a case-control study and a meta-analysis Ann Rheum Dis. 2007 Mar;66(3):320-4.
  • Tian L, Xie H, Yang T, Hu Y, Li J, Wang W. TNFR 2 M196R polymorphism and acne vulgaris in Han Chinese: a case-control study J Huazhong Univ Sci Technolog Med Sci. 2010 Jun;30(3):408-11.
  • González-Lara L, Batalla A, Coto E, Gómez J, Eiris N, Santos-Juanes J, Queiro R, Coto-Segura P. The TNFRSF1B rs1061622 polymorphism (p.M196R) is associated with biological drug outcome in Psoriasis patients Arch Dermatol Res. 2015 Jul;307(5):405-12.
  • Oregón-Romero E, Vázquez-Del Mercado M, Navarro-Hernández RE, Torres-Carrillo N, Martínez-Bonilla G, Estrada-García I, Rangel-Villalobos H, Muñoz-Valle JF. Tumor necrosis factor receptor 2 M196R polymorphism in rheumatoid arthritis and osteoarthritis: relationship with sTNFR2 levels and clinical features Rheumatol Int. 2006 Nov;27(1):53-9.
  • Rooryck C, Barnetche T, Richez C, Laleye A, Arveiler B, Schaeverbeke T. Influence of FCGR3A-V212F and TNFRSF1B-M196R genotypes in patients with rheumatoid arthritis treated with infliximab therapy Clin Exp Rheumatol. 2008 Mar-Apr;26(2):340-2.
  • Tian LM, Xie HF, Yang T, Hu YH, Li J, Wang WZ. Association study of tumor necrosis factor receptor type 2 M196R and toll-like receptor 2 Arg753Gln polymorphisms with acne vulgaris in a Chinese Han ethnic group Dermatology. 2010;221(3):276-84.
  • Gharaibeh AM, Awidi AS, Ababneh OH, Abu-Ameerh MA, Awidi MA, Saleh MM, Bener A, Al-Khateeb MA, Dweik MR, Albdour MD. Prevalence of thrombophilic genetic factors among patients with retinitis pigmentosa Retina. 2014 Oct;34(10):2147-50.
  • Ezquieta B, Oyarzabal M, Barrio R, Luzuriaga C, Hermoso F, Lechuga JL, Quinteiro S, Rodríguez A, Labarta JI, Gutierrez Macias A, Gallego M, Bellón JM. Monogenic and polygenic models detected in steroid 21-hydroxylase deficiency-related paediatric hyperandrogenism Horm Res. 2009 Jan;71(1):28-37.
  • Kuwahara A, Yamamori M, Fujita M, Okuno T, Tamura T, Kadoyama K, Okamura N, Nakamura T, Sakaeda T. TNFRSF1B A1466G genotype is predictive of clinical efficacy after treatment with a definitive 5-fluorouracil/cisplatin-based chemoradiotherapy in Japanese patients with esophageal squamous cell carcinoma J Exp Clin Cancer Res. 2010 Jul 20;29(1):100.

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Product Resources:

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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