Dextran Conjugated to Texas Red – Research Use Only

Texas Red–labeled dextrans are widely used fluorescent tracers for studying membrane permeability, endocytosis, intracellular trafficking, neuronal labeling, and macromolecular transport. This product line includes eight molecular weight variants (3–2000 kDa), enabling researchers to select size‑dependent diffusion and uptake characteristics appropriate for their experimental system. Each conjugate is supplied as a biotechnology‑grade solution, prepared in ultrapure water and sterile‑filtered for reproducible performance in imaging and biochemical workflows.

Available Molecular Weight Variants

Specifications

Scientific Overview

Texas Red–conjugated dextrans are hydrophilic fluorescent polysaccharides used extensively in cell biology, neuroscience, and imaging research. Their size‑dependent diffusion properties make them ideal for studying membrane permeability, macropinocytosis, synaptic vesicle cycling, and intracellular trafficking. Larger dextrans (500–2000 kDa) are commonly used to assess barrier integrity and extracellular diffusion, while smaller variants (3–20 kDa) are suited for endocytosis, vesicle labeling, and cytosolic tracking.

Common Research Applications

• Live‑cell and fixed‑cell fluorescence imaging
• Endocytosis and macropinocytosis assays
• Neuronal labeling and tracing
• Membrane permeability and barrier integrity studies
• Intracellular trafficking and vesicle dynamics
• Macromolecular diffusion and extracellular matrix transport

Usage & Handling Guidance

These conjugates are supplied as ready‑to‑use solutions. For experimental workflows, dilute in PBS, imaging buffer, or assay‑specific media. Protect from light during handling and storage. Avoid repeated freeze–thaw cycles to maintain fluorescence intensity.

• Light sensitivity: Protect from light
• Storage: −20 °C
• Avoid: repeated freeze–thaw cycles

What You Get

• 2.5 mg Texas Red–conjugated dextran
• Eight molecular weight variants (3–2000 kDa)
• Sterile‑filtered biotechnology‑grade solution
• For research use only (RUO)

Frequently Asked Questions

• How do I choose the appropriate molecular weight?
  Smaller dextrans (3–20 kDa) are typically used for endocytosis, vesicle labeling, and intracellular tracking, while larger dextrans (70–2000 kDa) are preferred for barrier integrity, extracellular diffusion, and permeability studies.
• Is this product suitable for in vivo diagnostic or therapeutic use?
  No. These conjugates are for in vitro research use only and are not intended for diagnostic or therapeutic applications.
• Can I obtain a COA or TDS for a specific clone?
  Yes. COA/TDS availability is batch dependent. Please contact us to request documentation for the catalog and lot being shipped.
• Can these conjugates be used in live‑cell imaging?
  Yes. Dextran–Texas Red conjugates are widely used in live‑cell imaging workflows, provided that appropriate concentrations, buffers, and light‑protection practices are followed.

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References

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