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Collagen Type II, Chicken Sternum Proteins Molecular Depot
Collagen Type II, Chicken Sternum Proteins Molecular Depot

Collagen Type II, Chicken Sternum

$795.00

    Catalog Number: B2019262 (1 mg)

    Collagen Type II from chicken sternum is a high‑purity native cartilage matrix protein widely used in extracellular matrix, immunological, and biochemical research. As the predominant collagen in hyaline cartilage, Type II collagen supports studies involving cartilage structure, chondrocyte biology, protein–matrix interactions, and collagen‑specific immune responses. Its stable powder format enables flexible use across biochemical, structural, and immunological workflows.Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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VR Headset

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Collagen Type II (Chicken Sternum) – Research Use Only

Catalog number: B2019262
Lot number: Batch dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight: N/A (heterogeneous collagen preparation)
Supplied as: Powder
Applications: Biochemical, immunological, and extracellular matrix research applications
Storage: Room temperature (RT)
Keywords: Collagen Type II, Chicken Sternum, Cartilage Matrix Protein
Grade: Biotechnology grade. Prepared with Type I ultrapure water (>18 MΩ·cm) and sterile‑filtered (0.22 µm).

Scientific Overview

Collagen Type II is the principal structural protein of hyaline cartilage and a key component of the extracellular matrix in joints. This preparation, isolated from chicken sternum cartilage, provides a high‑purity source of native Type II collagen suitable for biochemical assays, immunological studies, and cartilage‑related research models. Its defined origin and structural integrity make it a valuable tool for investigating cartilage biology, matrix composition, and collagen‑specific immune responses.

Common Research Applications

  • Extracellular matrix and cartilage biology research
  • Collagen‑specific antibody assays
  • Immunological studies, including collagen‑induced arthritis models
  • Biochemical characterization of collagen structure and stability
  • Protein–matrix interaction studies
  • Method development for collagen extraction and quantification

Usage & Handling Guidance

This product is supplied as a dry powder. For experimental use, researchers typically dissolve or suspend Type II collagen in dilute acetic acid, PBS, or assay‑specific buffers. Gentle mixing is recommended to maintain structural integrity. Aliquot after preparation to avoid repeated freeze–thaw cycles.

  • Reconstitution: Dilute acetic acid, PBS, or assay‑compatible buffer
  • Storage: Room temperature (powder); 2–8°C after reconstitution
  • Avoid: vigorous agitation and prolonged exposure to high temperatures

What You Get

  • 1 mg purified Type II collagen from chicken sternum
  • Native cartilage‑derived collagen matrix protein
  • Stable powder format for flexible experimental use
  • Biotechnology‑grade purity
  • For research use only (RUO)

Frequently Asked Questions

  • Is this product suitable for clinical or dietary use? No. This product is for research use only and is not intended for supplementation.
  • Is this collagen denatured? This preparation contains native Type II collagen derived from chicken sternum cartilage.
  • Can I obtain a COA or TDS? Documentation availability depends on the active batch. Please contact us to request COA/TDS for the lot being shipped.
  • Can this be used in collagen‑induced arthritis models? Type II collagen is commonly used in immunological research, including CIA model development.

References

  • Lugo JP, Saiyed ZM, Lane NE. Efficacy and tolerability of an undenatured type II collagen supplement in modulating knee osteoarthritis symptoms: a multicenter randomized, double-blind, placebo-controlled study Nutr J. 2016 Jan 29;15:14.
  • Lugo JP, Saiyed ZM, Lau FC, Molina JP, Pakdaman MN, Shamie AN, Udani JK. Undenatured type II collagen (UC-II®) for joint support: a randomized, double-blind, placebo-controlled study in healthy volunteers J Int Soc Sports Nutr. 2013 Oct 24;10(1):48.
  • Pates G, White T, Durkee S, Saiyed Z. UC-II® undenatured type II collagen data show retention during functional food and beverage prototype processing Data Brief. 2023 May 9;48:109216.
  • Luo C, Su W, Song Y, Srivastava S. Efficacy and safety of native type II collagen in modulating knee osteoarthritis symptoms: a randomised, double-blind, placebo-controlled trial J Exp Orthop. 2022 Dec 23;9(1):123.
  • Ata O, Bozdogan N, Mataraci CE, Kumcuoglu S, Kaya Bayram S, Tavman S. Extraction and characterization of valuable compounds from chicken sternal cartilage: Type II collagen and chondroitin sulfate Food Chem. 2025 Jan 1;462:141023.
  • Shiojima Y, Takahashi M, Takahashi R, Maruyama K, Moriyama H, Bagchi D, Bagchi M, Akanuma M. Efficacy and Safety of Dietary Undenatured Type II Collagen on Joint and Motor Function in Healthy Volunteers: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study J Am Nutr Assoc. 2023 Mar-Apr;42(3):224-241.
  • Akram AN, Zhang C. Extraction of collagen-II with pepsin and ultrasound treatment from chicken sternal cartilage; physicochemical and functional properties Ultrason Sonochem. 2020 Jun;64:105053.
  • Yoshinari O, Marone PA, Moriyama H, Shiojima Y. Safety and toxicological evaluation of a novel, water-soluble undenatured type II collagen Toxicol Mech Methods. 2013 Sep;23(7):491-9.
  • Rosloniec EF, Cremer M, Kang A, Myers LK. Collagen-induced arthritis Curr Protoc Immunol. 2001 May;Chapter 15:15.5.1-15.5.24.

    Terms & Conditions

    Blue Tiger Scientific is an independent third-party distributor of select products manufactured by Molecular Depot LLC. By purchasing from bluetigerscientific.com, you (“the Customer”) agree to the following terms, adapted from Molecular Depot’s original conditions:

    Product Use & Eligibility
    Products are for in vitro research use only (RUO). They are not intended for human or animal use, diagnosis, therapy, resale to consumers, or residential delivery. Sales are limited to verified business addresses.

    Payment Terms
    All purchases are prepaid and non-refundable once confirmed. Pricing is in USD and subject to change without notice.

    Purchase Orders
    Confirmed orders are final and may not be canceled or refunded unless authorized in writing.

    Limitation of Liability
    Blue Tiger Scientific and Molecular Depot LLC are not responsible for any damages resulting from product use or misuse.

    Waiver of Claims
    By ordering, you waive all claims arising from use of Molecular Depot products.

    Shipping & Handling
    Shipping is calculated at checkout. A minimum 27% handling fee applies to each order.

    Delivery Estimates All delivery timelines are estimates and not guaranteed. FedEx service levels are subject to operational delays, weather disruptions, and regional restrictions.

    FedEx Pickup Cutoff Orders submitted after the daily FedEx pickup window may not ship until the next available pickup day.

    Shipping Exceptions FedEx may impose restrictions or delays due to package size, weight, destination, or service availability. Blue Tiger Scientific is not liable for delays beyond our control.

    Weekend & Holiday Handling Orders placed on weekends or holidays will be processed on the next business day.

    Returns & Refunds
    Returns must be requested within 30 days through Blue Tiger Scientific. Refunds are only issued for shipping errors or verified defects, and processed within 45 business days if approved. Customers are responsible for return shipping costs unless otherwise stated. Refunds will exclude original shipping fees paid at checkout.

    Warranty Disclaimer
    All products are provided "as-is" with no warranties. Warranty issues are handled by the manufacturer.

    Safety Guidelines
    Always consult the product’s SDS. Products must not be ingested, inhaled, or come into contact with skin or eyes unless specified.

    Legal Use Compliance
    Products must not be used in violation of any law—local, state, federal, or international.

    Accuracy of Orders
    Customers are responsible for verifying all order details before submission.

    Changes or Cancellations
    All changes must be in writing and approved. Cancellations may result in fees for materials, labor, or third-party costs.

    Quality System (MD Levels)
    Molecular Depot’s MD-Quality System includes:

    MD 1000: Non-regulated use, no change notification

    MD 2000: Non-regulated use, limited change notification

    MD 3000: Regulated use, enhanced quality standards

    Delivery & Claims
    Orders may ship in parts. Claims for shortages or defects must be submitted within 2 days of receipt. Delivery dates are estimates only.

    Extended Payment Terms
    Payment is due within 30 days unless agreed otherwise. A 5% weekly penalty applies to late payments. Blue Tiger Scientific reserves discretion on payment application.

    Retention of Title
    Ownership remains with Blue Tiger Scientific or Molecular Depot LLC until payment is complete. Goods must be stored separately and labeled until paid in full.

    Intellectual Property
    No rights to manufacturing processes or IP are transferred. Blue Tiger Scientific is not liable for IP-related claims.

    Force Majeure
    Neither party is liable for delays or failures caused by uncontrollable events (e.g., weather, regulations, supply disruptions).

    Manufacturing Access
    Product purchase does not grant access to proprietary manufacturing documents or methods.

    Resale Prohibition
    Products cannot be resold without written approval from Molecular Depot LLC. Blue Tiger Scientific enforces this restriction.

    Governing Law
    Terms are governed by California and U.S. law. All disputes fall under U.S. jurisdiction.

Product Resources:

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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