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CLE25 Peptide (Highly Pure) Peptides Molecular Depot
CLE25 Peptide (Highly Pure) Peptides Molecular Depot
CLE25 Peptide (Highly Pure) Peptides Molecular Depot
CLE25 Peptide (Highly Pure) Peptides Molecular Depot
CLE25 Peptide (Highly Pure) Peptides Molecular Depot
CLE25 Peptide (Highly Pure) Peptides Molecular Depot

CLE25 Peptide (Highly Pure)

$647.00

    CLE25 Peptide is a synthetic peptide consisting of the sequence: Arg-Lys-Val-Hyp-Asn-Gly-Hyp-Asp-Pro-Ile-His-Asn. The molecular weight of this peptide is 1375.5 g/mol a=. This product is for in vitro research use only. This product is not for human or animal use. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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CLE25 Peptide (Highly Pure)

Catalog # MDP0859
Name Arg-Lys-Val-Hyp-Asn-Gly-Hyp-Asp-Pro-Ile-His-Asn
Synonyms CLE25 Peptide
Molecular Formula C₅₈H₉₄N₂₀O₁₉
Molecular Mass 1375.5 g/mol
Storage −20°C

CLE25 Peptide is a synthetic plant signaling peptide derived from Arabidopsis thaliana, known for its role in long-distance communication and developmental regulation. This 12-residue peptide sequence includes hydroxyproline modifications and is involved in modulating stomatal closure via abscisic acid signaling, particularly under drought stress conditions. CLE25 has also been shown to regulate phloem initiation and root protophloem differentiation through receptor complexes such as CLERK-CLV2 and BAM-CIK modules.

Researchers use CLE25 to investigate stem cell maintenance, shoot and root meristem homeostasis, and hormonal crosstalk in plant development. It is a valuable tool for dissecting peptide-mediated signaling pathways, understanding vascular patterning, and exploring transcriptomic responses in fruit retention and abscission zones. This peptide supports high-resolution studies in plant molecular biology, crop improvement, and synthetic biology applications.

Supplied as a highly pure lyophilized powder, CLE25 Peptide is ideal for in vitro assays, receptor binding studies, and functional genomics. It is intended for Research Use Only (RUO) and not for diagnostic or therapeutic applications.

Key Features:

  • 12-residue synthetic CLE25 peptide with hydroxyproline modifications
  • Validated for use in Arabidopsis signaling and vascular development studies
  • Molecular Mass: 1375.5 g/mol; Storage: −20°C
  • RUO designation: not for clinical or therapeutic applications

Use:
This product is for Research Use Only (RUO). It is not intended for human or animal use, diagnostic procedures, or therapeutic applications.

Safety:
Users must review the Safety Data Sheet (SDS) prior to handling. Avoid ingestion, inhalation, or contact with eyes, skin, or clothing.

References:

1: Ren SC, Song XF, Chen WQ, Lu R, Lucas WJ, Liu CM. CLE25 peptide regulates phloem initiation in Arabidopsis through a CLERK-CLV2 receptor complex J Integr Plant Biol. 2019 Oct;61(10):1043-1061.
2: Takahashi F, Suzuki T, Osakabe Y, Betsuyaku S, Kondo Y, Dohmae N, Fukuda H, Yamaguchi-Shinozaki K, Shinozaki K. A small peptide modulates stomatal control via abscisic acid in long-distance signalling Nature. 2018 Apr;556(7700):235-238.
3: McLachlan DH, Pridgeon AJ, Hetherington AM. How Arabidopsis Talks to Itself about Its Water Supply Mol Cell. 2018 Jun 21;70(6):991-992.
4: Hu C, Zhu Y, Cui Y, Zeng L, Li S, Meng F, Huang S, Wang W, Kui H, Yi J, Li J, Wan D, Gou X. A CLE-BAM-CIK signalling module controls root protophloem differentiation in Arabidopsis New Phytol. 2022 Jan;233(1):282-296.
5: Song XF, Hou XL, Liu CM. CLE peptides: critical regulators for stem cell maintenance in plants Planta. 2021 Nov 29;255(1):5.
6: Sriskantharajah K, El Kayal W, Torkamaneh D, Ayyanath MM, Saxena PK, Sullivan AJ, Paliyath G, Subramanian J. Transcriptomics of Improved Fruit Retention by Hexanal in ‘Honeycrisp’ Reveals Hormonal Crosstalk and Reduced Cell Wall Degradation in the Fruit Abscission Zone Int J Mol Sci. 2021 Aug 17;22(16):8830.
7: Wang W, Hu C, Li X, Zhu Y, Tao L, Cui Y, Deng D, Fan X, Zhang H, Li J, Gou X, Yi J. Receptor-like cytoplasmic kinases PBL34/35/36 are required for CLE peptide-mediated signaling to maintain shoot apical meristem and root apical meristem homeostasis in Arabidopsis Plant Cell. 2022 Mar 29;34(4):1289-1307.

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    Product Use & Eligibility
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Product Resources:

Manual Manual
Brochure Brochure

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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