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Citrullinated β-Catenin (human, recombinant) Proteins Molecular Depot
Citrullinated β-Catenin (human, recombinant) Proteins Molecular Depot

Citrullinated β-Catenin (human, recombinant)

$2,195.00

    Catalog Number: B2017285 (100 µg)

    Citrullinated β-Catenin (human, recombinant) is a lab-produced version of the human β-Catenin protein modified by citrullination. β-Catenin regulates cell adhesion and gene transcription, part of the Wnt signaling pathway. Citrullination, a post-translational modification, converts arginine to citrulline, affecting protein function. This protein is used in research to study its role in diseases. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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Manufacturer Warranty

All products are covered by manufacturer warranty

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What's Included

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VR Headset

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2 Touch Controllers

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Charging Cable

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Power Adapter

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Glasses Spacer

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Citrullinated β-Catenin (human, recombinant)

Catalog number: B2017285
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 µg
Molecular Weight or Concentration: 72 kDa
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: −80°C
Keywords: Catenin β-1, CTNNB1, Catenin (Cadherin-Associated Protein), β1, 88kDa, EVR7, MRD19, NEDSDV
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References

  • Qu Y, Olsen JR, Yuan X, Cheng PF, Levesque MP, Brokstad KA, Hoffman PS, Oyan AM, Zhang W, Kalland KH, Ke X. Small molecule promotes β-catenin citrullination and inhibits Wnt signaling in cancer Nat Chem Biol. 2018 Jan;14(1):94-101.
  • Tsai CY, Hsieh SC, Liu CW, Lu CH, Liao HT, Chen MH, Li KJ, Wu CH, Shen CY, Kuo YM, Yu CL. The Expression of Non-Coding RNAs and Their Target Molecules in Rheumatoid Arthritis: A Molecular Basis for Rheumatoid Pathogenesis and Its Potential Clinical Applications Int J Mol Sci. 2021 May 26;22(11):5689.
  • Zhou J, Biesterveld BE, Li Y, Wu Z, Tian Y, Williams AM, Tian S, Gao W, Bhatti UF, Duan X, Wang T, Zhang J, Jiang B, Wang Z, Alam HB. Peptidylarginine Deiminase 2 Knockout Improves Survival in hemorrhagic shock Shock. 2020 Oct;54(4):458-463.
  • Gijon M, Metheringham RL, Toss MS, Paston SJ, Durrant LG. The Clinical and Prognostic Significance of Protein Arginine Deiminases 2 and 4 in Colorectal Cancer Pathobiology. 2022;89(1):38-48.
  • Chen DQ, Cao G, Chen H, Liu D, Su W, Yu XY, Vaziri ND, Liu XH, Bai X, Zhang L, Zhao YY. Gene and protein expressions and metabolomics exhibit activated redox signaling and wnt/β-catenin pathway are associated with metabolite dysfunction in patients with chronic kidney disease Redox Biol. 2017 Aug;12:505-521.
  • Miao CG, Huang C, Huang Y, Yang YY, He X, Zhang L, Lv XW, Jin Y, Li J. MeCP2 modulates the canonical Wnt pathway activation by targeting SFRP4 in rheumatoid arthritis fibroblast-like synoviocytes in rats Cell Signal. 2013 Mar;25(3):598-608.
  • Bowden TJ, Kraev I, Lange S. Extracellular Vesicles and Post-Translational Protein Deimination Signatures in Mollusca-The Blue Mussel (Mytilus edulis), Soft Shell Clam (Mya arenaria), Eastern Oyster (Crassostrea virginica) and Atlantic Jacknife Clam (Ensis leei) Biology (Basel). 2020 Nov 25;9(12):416.
  • Liu J, Xiao Q, Xiao J, Niu C, Li Y, Zhang X, Zhou Z, Shu G, Yin G. Wnt/β-catenin signalling: function, biological mechanisms, and therapeutic opportunities Signal Transduct Target Ther. 2022 Jan 3;7(1):3.
  • Yu F, Yu C, Li F, Zuo Y, Wang Y, Yao L, Wu C, Wang C, Ye L. Wnt/β-catenin signaling in cancers and targeted therapies Signal Transduct Target Ther. 2021 Aug 30;6(1):307.

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    Blue Tiger Scientific is an independent third-party distributor of select products manufactured by Molecular Depot LLC. By purchasing from bluetigerscientific.com, you (“the Customer”) agree to the following terms, adapted from Molecular Depot’s original conditions:

    Product Use & Eligibility
    Products are for in vitro research use only (RUO). They are not intended for human or animal use, diagnosis, therapy, resale to consumers, or residential delivery. Sales are limited to verified business addresses.

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    All purchases are prepaid and non-refundable once confirmed. Pricing is in USD and subject to change without notice.

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    MD 2000: Non-regulated use, limited change notification

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Product Resources:

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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