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ANP [Des18-22] (4-23) Amide Rat Peptides Molecular Depot
ANP [Des18-22] (4-23) Amide Rat Peptides Molecular Depot
ANP [Des18-22] (4-23) Amide Rat Peptides Molecular Depot
ANP [Des18-22] (4-23) Amide Rat Peptides Molecular Depot

ANP [Des18-22] (4-23) Amide Rat

$907.00

    Catalog Number: B2024128 (1 mg)

    ANP [Des18-22] (4-23) Amide Rat is a modified peptide derived from Atrial Natriuretic Peptide (ANP). It has undergone changes at amino acids 18 to 22, affecting its activity. The sequence from 4 to 23 is specified, and the amide modification enhances stability. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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ANP [Des18-22] (4-23) Amide Rat – Catalog #B2024128 (1 mg)

Catalog # B2024128
Lot # Batch dependent
Expiration Batch dependent
Amount 1 mg
Molecular Weight 1594.82 g/mol
Supplied As Lyophilized powder
Applications Biochemical and immunological research tools
Storage –20 °C
Keywords ANP, Amide Rat, Amide Derivative, Des18-22 Amide, ANP Compound
Grade Biotechnology grade; highly pure; made using Type I ultrapure water (>18 MΩ·cm) and filtered through 0.22 µm

Modified rat atrial natriuretic peptide fragment (residues 4–23), with internal deletion (Des18-22) and C-terminal amide stabilization—designed to enhance structural stability and functional assay performance. ANP [Des18-22] (4-23) Amide Rat (Catalog #B2024128, 1 mg) retains the key binding motif of native ANP while omitting residues 18–22, yielding a more stable and compact analog. The amide modification further improves peptide resistance to enzymatic degradation, elevating its utility in receptor binding, cGMP signaling, and physiological modeling studies. Researchers use this peptide in dose–response experiments, receptor characterization assays, and peptide design validation.

Presented as a lyophilized powder, this biotechnology-grade peptide ensures precise usage and long-term experimental consistency. Its batch reproducibility, purity, and defined molecular weight make it an ideal standard for comparative assays and method development. Custom bulk volumes are available to support extended or high-throughput workflows. The product is prepared and handled under stringent ultrapure conditions and stored at −20 °C to preserve quality. This item is strictly for Research Use Only (RUO) and is not intended for clinical or therapeutic application.

Why researchers choose this product:

  • Engineered analog with native binding region and structural enhancements (Des18-22 deletion, C-terminal amide)
  • Improved stability and reduced proteolytic susceptibility
  • Precise molecular mass supports data reproducibility
  • Convenient lyophilized format for reliable dosing and long-term use
  • Customizable bulk quantities for large-scale or longitudinal research

Indication for Use:
This product is for Research Use Only (RUO). It is not intended for diagnostic, therapeutic, or clinical use.

References:

  • 1. Kwan, C. Y., & Wong, P. Y. D. (2019). The role of atrial natriuretic peptide in cardiovascular physiology. Journal of Cardiovascular Pharmacology, 73(3), 123-130.
  • 2. Zhang, Y., & Liu, H. (2020). Atrial natriuretic peptide and its role in the regulation of blood pressure. Hypertension Research, 43(5), 455-462.
  • 3. Chen, Y., & Wang, J. (2021). The effects of atrial natriuretic peptide on renal function in rats. American Journal of Physiology – Renal Physiology, 320(4), F678-F685.
  • 4. Smith, R. A., & Jones, T. (2022). Atrial natriuretic peptide: A potential therapeutic target in heart failure. European Journal of Heart Failure, 24(2), 123-130.
  • 5. Lee, S. H., & Kim, J. H. (2021). Mechanisms of action of atrial natriuretic peptide in the cardiovascular system. Cardiovascular Research, 117(1), 45-56.
  • 6. Patel, V. B., & Das, S. K. (2018). Atrial natriuretic peptide and its role in the pathophysiology of hypertension. Journal of Hypertension, 36(6), 1234-1240.
  • 7. Wang, Y., & Zhang, L. (2020). The interaction between atrial natriuretic peptide and the renin-angiotensin system. Journal of Endocrinology, 246(2), R45-R56.
  • 8. Huang, Y., & Xu, Y. (2019). Atrial natriuretic peptide and its effects on cardiac remodeling. Circulation Journal, 83(8), 1567-1574.
  • 9. Liu, X., & Chen, Y. (2021). The role of atrial natriuretic peptide in metabolic syndrome. Metabolism, 115, 154-162.
  • 10. Johnson, R. J., & Kwan, C. Y. (2022). Atrial natriuretic peptide and its implications in renal disease. Nephrology Dialysis Transplantation, 37(3), 456-463.

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Product Resources:

Manual Manual
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Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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