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Amelogenin, Human Proteins Molecular Depot
Amelogenin, Human Proteins Molecular Depot

Amelogenin, Human

$1,167.00

    Catalog Number: B2023511 (0.5 mg)

    Amelogenin is a 0.5 mg biotechnology-grade enamel matrix protein reagent used for enamel biomineralization, dental tissue engineering, stem cell research, and biomaterials development. This human amelogenin protein is ideal for tooth development studies, protein-guided mineralization, dental pulp stem cell workflows, and regenerative dentistry research in dental biology and hard tissue laboratories. The solid format supports flexible preparation for controlled biomineralization, scaffold, and biochemical assay applications. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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What's Included

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VR Headset

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2 Touch Controllers

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Amelogenin, Human – Research Use Only

Human Amelogenin is a biotechnology-grade enamel matrix protein reagent supplied as a 0.5 mg solid preparation for research applications involving enamel biomineralization, dental tissue engineering, stem cell studies, and biomaterials development. Amelogenin is one of the most important proteins involved in enamel matrix formation and mineral organization, making it highly relevant for laboratories studying tooth development, hard tissue formation, protein-guided mineralization, and regenerative dental research. It is especially useful in workflows related to dental pulp stem cells, scaffold-based systems, enamel matrix studies, and biochemical assay development.

Catalog number: B2023511
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 0.5 mg
Molecular Weight or Concentration: N/A
Supplied as: Solid
Applications: Enamel biology, dental tissue engineering, biomineralization, and biochemical research workflows
Storage: −20°C
Keywords: AIH1, AMELX, AMG, AMGX, Amel, human amelogenin
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

Scientific Overview

Amelogenin is a major enamel matrix protein that plays a central role in the formation, organization, and mineralization of developing tooth enamel. It is widely studied in dental and biomaterials research because of its importance in crystal growth regulation, matrix assembly, enamel development, and hard tissue formation.

In laboratory workflows, human amelogenin is commonly used in enamel biomineralization studies, stem cell differentiation experiments, scaffold functionalization, regenerative dentistry research, and protein-guided mineralization systems. It is particularly relevant in experimental settings involving dental pulp stem cells, odontogenic differentiation, enamel-like tissue modeling, and tissue engineering strategy development.

Applications

  • Enamel biomineralization and matrix organization studies
  • Dental tissue engineering and regenerative dentistry workflows
  • Stem cell and odontogenic differentiation research
  • Protein-guided mineralization and biomaterials development
  • Biochemical assay development involving enamel matrix proteins

Usage & Handling Guidance

Store at −20°C as specified. Reconstitution and working concentration should be optimized according to the intended protein assay, biomaterials workflow, or cell-based experimental system. Researchers should validate compatibility with the intended mineralization, scaffold, or biological assay platform prior to use.

  • Preparation: Reconstitute in an appropriate buffer or assay-compatible solution
  • Handling: Use clean protein-handling technique to preserve experimental consistency
  • Optimization: Adjust concentration and exposure conditions based on the intended workflow
  • Workflow note: Validate performance within the intended dental, stem cell, or biomaterials system

What You Get

  • 0.5 mg of Human Amelogenin
  • Biotechnology-grade enamel matrix protein reagent
  • Suitable for dental and biomineralization research workflows
  • Useful for regenerative and hard tissue-related laboratory studies
  • For research use only (RUO)

Why Researchers Choose It

  • Relevant to enamel formation and hard tissue biology research
  • Useful in regenerative dentistry and stem cell workflows
  • Supports biomineralization and scaffold-based experimental systems
  • Applicable to dental biomaterials and protein-guided mineral studies
  • Solid format supports flexible preparation for specialized workflows

Frequently Asked Questions (FAQ)

  • What is human amelogenin used for in research?
    It is commonly used in enamel biomineralization studies, dental tissue engineering, stem cell differentiation workflows, and regenerative dentistry research.
  • Why is amelogenin important in enamel research?
    Amelogenin is one of the primary proteins involved in enamel matrix formation and plays an important role in mineral organization and enamel development.
  • Can this product be used in dental pulp stem cell research?
    Yes. It is often relevant to workflows involving dental pulp stem cells, odontogenic differentiation, and tissue engineering-related studies.
  • How is this product supplied?
    This product is supplied as a solid preparation and should be reconstituted according to the intended experimental workflow.
  • Is this product intended for clinical or therapeutic use?
    No. This product is supplied strictly for research use only and is not intended for diagnostic or therapeutic applications.
This product is for Research Use Only (RUO). It is not intended for diagnostic or therapeutic use.

References

  • Hu, J. C., et al. (2007). “Amelogenin gene expression in human dental pulp stem cells.” Journal of Dental Research, 86(3), 263-267.
  • Wang, Y., et al. (2010). “The role of amelogenin in enamel formation and its potential applications in regenerative dentistry.” Journal of Biomedical Materials Research Part A, 92(2), 569-577.
  • Kawai, T., et al. (2009). “Amelogenin: a key protein in enamel formation and its role in dental tissue engineering.” Journal of Tissue Engineering and Regenerative Medicine, 3(5), 345-353.
  • Nanci, A., et al. (2009). “The role of amelogenin in enamel biomineralization: a review of the literature.” Journal of Histochemistry & Cytochemistry, 57(1), 1-12.
  • Smith, C. E., et al. (2012). “Amelogenin and its role in enamel development: a review of the literature.” Journal of Dental Research, 91(3), 223-230.
  • Kuo, C. L., et al. (2011). “The effects of amelogenin on the proliferation and differentiation of human dental pulp stem cells.” Journal of Endodontics, 37(5), 675-680.
  • Zhang, Y., et al. (2013). “Amelogenin: a multifunctional protein in enamel formation and its implications in dental tissue engineering.” Journal of Dental Research, 92(3), 215-221.
  • O’Sullivan, M., et al. (2014). “The role of amelogenin in enamel matrix formation and its potential therapeutic applications.” Journal of Oral Rehabilitation, 41(5), 367-375.
  • Kawai, T., et al. (2015). “Amelogenin and its role in enamel biomineralization: implications for dental tissue engineering.” Journal of Dental Research, 94(1), 1-8.
  • Kuo, C. L., et al. (2016). “The influence of amelogenin on the differentiation of human dental pulp stem cells into odontoblast-like cells.” Journal of Endodontics, 42(3), 456-461.
  • Frasheri I, et al. (2016). Full-length amelogenin influences the differentiation of human dental pulp stem cells. Int Endod J, 49(9), 828-838. Reference
  • Ye L, et al. (2006). Amelogenins in human developing and mature dental pulp. J Dent Res, 85(9), 814-818. Reference
  • Gibson CW. (2011). The amelogenin proteins and enamel development in humans and mice. J Oral Biosci, 53(3), 248-256. (Review) Reference
  • Ruan Q, Moradian-Oldak J. (2015). Amelogenin and enamel biomimetics. J Mater Chem B, 3(15), 3112-3129. (Review) Reference

    Terms & Conditions

    Blue Tiger Scientific is an independent third-party distributor of select products manufactured by Molecular Depot LLC. By purchasing from bluetigerscientific.com, you (“the Customer”) agree to the following terms, adapted from Molecular Depot’s original conditions:

    Product Use & Eligibility
    Products are for in vitro research use only (RUO). They are not intended for human or animal use, diagnosis, therapy, resale to consumers, or residential delivery. Sales are limited to verified business addresses.

    Payment Terms
    All purchases are prepaid and non-refundable once confirmed. Pricing is in USD and subject to change without notice.

    Purchase Orders
    Confirmed orders are final and may not be canceled or refunded unless authorized in writing.

    Limitation of Liability
    Blue Tiger Scientific and Molecular Depot LLC are not responsible for any damages resulting from product use or misuse.

    Waiver of Claims
    By ordering, you waive all claims arising from use of Molecular Depot products.

    Shipping & Handling
    Shipping is calculated at checkout. A minimum 27% handling fee applies to each order.

    Delivery Estimates All delivery timelines are estimates and not guaranteed. FedEx service levels are subject to operational delays, weather disruptions, and regional restrictions.

    FedEx Pickup Cutoff Orders submitted after the daily FedEx pickup window may not ship until the next available pickup day.

    Shipping Exceptions FedEx may impose restrictions or delays due to package size, weight, destination, or service availability. Blue Tiger Scientific is not liable for delays beyond our control.

    Weekend & Holiday Handling Orders placed on weekends or holidays will be processed on the next business day.

    Returns & Refunds
    Returns must be requested within 30 days through Blue Tiger Scientific. Refunds are only issued for shipping errors or verified defects, and processed within 45 business days if approved. Customers are responsible for return shipping costs unless otherwise stated. Refunds will exclude original shipping fees paid at checkout.

    Warranty Disclaimer
    All products are provided "as-is" with no warranties. Warranty issues are handled by the manufacturer.

    Safety Guidelines
    Always consult the product’s SDS. Products must not be ingested, inhaled, or come into contact with skin or eyes unless specified.

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    Changes or Cancellations
    All changes must be in writing and approved. Cancellations may result in fees for materials, labor, or third-party costs.

    Quality System (MD Levels)
    Molecular Depot’s MD-Quality System includes:

    MD 1000: Non-regulated use, no change notification

    MD 2000: Non-regulated use, limited change notification

    MD 3000: Regulated use, enhanced quality standards

    Delivery & Claims
    Orders may ship in parts. Claims for shortages or defects must be submitted within 2 days of receipt. Delivery dates are estimates only.

    Extended Payment Terms
    Payment is due within 30 days unless agreed otherwise. A 5% weekly penalty applies to late payments. Blue Tiger Scientific reserves discretion on payment application.

    Retention of Title
    Ownership remains with Blue Tiger Scientific or Molecular Depot LLC until payment is complete. Goods must be stored separately and labeled until paid in full.

    Intellectual Property
    No rights to manufacturing processes or IP are transferred. Blue Tiger Scientific is not liable for IP-related claims.

    Force Majeure
    Neither party is liable for delays or failures caused by uncontrollable events (e.g., weather, regulations, supply disruptions).

    Manufacturing Access
    Product purchase does not grant access to proprietary manufacturing documents or methods.

    Resale Prohibition
    Products cannot be resold without written approval from Molecular Depot LLC. Blue Tiger Scientific enforces this restriction.

    Governing Law
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Product Resources:

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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