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Acetyl-Calpastatin (184-210) (Human) Proteins Molecular Depot
Acetyl-Calpastatin (184-210) (Human) Proteins Molecular Depot
Acetyl-Calpastatin (184-210) (Human) Proteins Molecular Depot
Acetyl-Calpastatin (184-210) (Human) Proteins Molecular Depot

Acetyl-Calpastatin (184-210) (Human)

$1,795.00

    Catalog Number: B2019116 (1 mg)

    Acetyl-Calpastatin (184-210) is a peptide derived from calpastatin, a specific inhibitor of calpain. It regulates calpain activity, which is involved in cellular processes. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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VR Headset

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2 Touch Controllers

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Acetyl-Calpastatin (184-210) (Human)

Catalog number: B2019116
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: N/A
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: −20°C
Keywords: Calpastatin|123714-50-1|Calpastatin Peptide B27-WT|AC-ASP-PRO-MET-SER-SER-THR-TYR-ILE-GLU-GLU-LEU-GLY-LYS-ARG-GLU-VAL-THR-ILE-PRO-PRO-LYS-TYR-ARG-GLU-L|acetyl-calpastatin (184-210)|CHEBI:131884|calpastatin peptide Ac 184-210|Ac-calpastatin(184-210)(human)
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References

  • Fiorino F, Gil-Parrado S, Assfalg-Machleidt I, Machleidt W, Moroder L. A new cell-permeable calpain inhibitor J Pept Sci. 2007 Jan;13(1):70-3.
  • Squier MK, Sehnert AJ, Sellins KS, Malkinson AM, Takano E, Cohen JJ. Calpain and calpastatin regulate neutrophil apoptosis J Cell Physiol. 1999 Mar;178(3):311-9.
  • Peintner L, Venkatraman A, Waeldin A, Hofherr A, Busch T, Voronov A, Viau A, Kuehn EW, Köttgen M, Borner C. Loss of PKD1/polycystin-1 impairs lysosomal activity in a CAPN (calpain)-dependent manner Autophagy. 2021 Sep;17(9):2384-2400.
  • Kato M, Nonaka T, Maki M, Kikuchi H, Imajoh-Ohmi S. Caspases cleave the amino-terminal calpain inhibitory unit of calpastatin during apoptosis in human Jurkat T cells J Biochem. 2000 Feb;127(2):297-305.
  • Seo J, Jo SA, Hwang S, Byun CJ, Lee HJ, Cho DH, Kim D, Koh YH, Jo I. Trichostatin A epigenetically increases calpastatin expression and inhibits calpain activity and calcium-induced SH-SY5Y neuronal cell toxicity FEBS J. 2013 Dec;280(24):6691-701.
  • Gil-Parrado S, Assfalg-Machleidt I, Fiorino F, Deluca D, Pfeiler D, Schaschke N, Moroder L, Machleidt W. Calpastatin exon 1B-derived peptide, a selective inhibitor of calpain: enhancing cell permeability by conjugation with penetratin Biol Chem. 2003 Mar;384(3):395-402.
  • Yang H, Murthy S, Sarkar FH, Sheng S, Reddy GP, Dou QP. Calpain-mediated androgen receptor breakdown in apoptotic prostate cancer cells J Cell Physiol. 2008 Dec;217(3):569-76.
  • Gil-Parrado S, Fernández-Montalván A, Assfalg-Machleidt I, Popp O, Bestvater F, Holloschi A, Knoch TA, Auerswald EA, Welsh K, Reed JC, Fritz H, Fuentes-Prior P, Spiess E, Salvesen GS, Machleidt W. Ionomycin-activated calpain triggers apoptosis. A probable role for Bcl-2 family members J Biol Chem. 2002 Jul 26;277(30):27217-26.
  • Kim H, Zamel R, Bai XH, Lu C, Keshavjee S, Keshavjee S, Liu M. Ischemia-reperfusion induces death receptor-independent necroptosis via calpain-STAT3 activation in a lung transplant setting Am J Physiol Lung Cell Mol Physiol. 2018 Oct 1;315(4):L595-L608.

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Product Resources:

Manual Manual
Brochure Brochure

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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