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360 MMP FRET Substrate III Chemicals Molecular Depot
360 MMP FRET Substrate III Chemicals Molecular Depot
360 MMP FRET Substrate III Chemicals Molecular Depot
360 MMP FRET Substrate III Chemicals Molecular Depot

360 MMP FRET Substrate III

$795.00

    Catalog Number: B2019464 (2 mg)

    360 MMP FRET Substrate III is a biochemical substrate for fluorescence resonance energy transfer (FRET) assays. It emits fluorescence around 360 nm when cleaved by specific matrix metalloproteinases (MMPs), allowing for the quantification of MMP activity in biological samples. This substrate aids in understanding the role of MMPs in various processes. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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What's Included

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VR Headset

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2 Touch Controllers

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Charging Cable

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Power Adapter

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360 MMP FRET Substrate III

Catalog number: B2019464
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 2 mg
Molecular Weight or Concentration: 1012.1
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: -20°C
Keywords: Dnp-PLGMWSR
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References

  • Wang L, Saarela J, Poque S, Valkonen JPT. Development of FRET-based high-throughput screening for viral RNase III inhibitors Mol Plant Pathol. 2020 Jul;21(7):961-974.
  • Comeau MA, Lafontaine DA, Abou Elela S. The catalytic efficiency of yeast ribonuclease III depends on substrate specific product release rate Nucleic Acids Res. 2016 Sep 19;44(16):7911-21.
  • Eskonen V, Tong-Ochoa N, Mattsson L, Miettinen M, Lastusaari M, Pulliainen AT, Kopra K, Härmä H. Single-Peptide TR-FRET Detection Platform for Cysteine-Specific Post-Translational Modifications Anal Chem. 2020 Oct 6;92(19):13202-13210.
  • Hu T, Ma C, Yan Y, Chen J. Detection of DNA Methyltransferase Activity via Fluorescence Resonance Energy Transfer and Exonuclease-Mediated Target Recycling Biosensors (Basel). 2022 Jun 8;12(6):395.
  • Baumgarten J, Schneider P, Thiemann M, Zimmermann M, Diederich C, Blankenfeldt W, Kunick C. Substrate-Based Ligand Design for Phenazine Biosynthesis Enzyme PhzF ChemMedChem. 2024 Aug 20:e202400466.
  • Jin H, Liu R, Bai T, Wei M, He B, Suo Z. A low-noise ratiometric fluorescence biosensor for detection of Pb(2+) based on DNAzyme and exonuclease III-assisted cascade signal amplification Anal Bioanal Chem. 2022 Feb;414(5):1899-1907.
  • Lafontaine DA, Norman DG, Lilley DM. The global structure of the VS ribozyme EMBO J. 2002 May 15;21(10):2461-71.
  • Sedighi A, Krull UJ. Enzymatic amplification of oligonucleotides in paper substrates Talanta. 2018 Aug 15;186:568-575.
  • Bourdès A, Rudder S, East AK, Poole PS. Mining the Sinorhizobium meliloti transportome to develop FRET biosensors for sugars, dicarboxylates and cyclic polyols PLoS One. 2012;7(9):e43578.

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Product Resources:

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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