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Z-Val-Ala-Asp Fluoromethyl Ketone Chemicals Molecular Depot
Z-Val-Ala-Asp Fluoromethyl Ketone Chemicals Molecular Depot
Z-Val-Ala-Asp Fluoromethyl Ketone Chemicals Molecular Depot
Z-Val-Ala-Asp Fluoromethyl Ketone Chemicals Molecular Depot

Z-Val-Ala-Asp Fluoromethyl Ketone

$995.00

    Catalog Number: B2013836 (1.5 mg)

    Z-Val-Ala-Asp Fluoromethyl Ketone is a high quality Non-methylated competitive and irreversible inhibitor of caspase-1. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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What's Included

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VR Headset

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2 Touch Controllers

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Charging Cable

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Power Adapter

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Glasses Spacer

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Z-Val-Ala-Asp Fluoromethyl Ketone

Catalog number: B2013836
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1.5 mg
Molecular Weight or Concentration: 453.46 g/mol
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: −20°C
Keywords: Z-VAD-FMK, Non-methylated
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References

  • Chu J, Liu CX, Song R, Li QL. Ferrostatin-1 protects HT-22 cells from oxidative toxicity Neural Regen Res. 2020 Mar;15(3):528-536.
  • Atar O, Avraham KB. Anti-apoptotic factor z-Val-Ala-Asp-fluoromethylketone promotes the survival of cochlear hair cells in a mouse model for human deafness Neuroscience. 2010 Jul 14;168(3):851-7.
  • Kugawa F, Ueno A, Aoki M. Apoptosis of NG108-15 cells induced by buprenorphine hydrochloride occurs via the caspase-3 pathway Biol Pharm Bull. 2000 Aug;23(8):930-5.
  • Fei XF, Wang BX, Tashiro S, Li TJ, Ma JS, Ikejima T. Apoptotic effects of ginsenoside Rh2 on human malignant melanoma A375-S2 cells Acta Pharmacol Sin. 2002 Apr;23(4):315-22.
  • Yang HL, Liu HW, Shrestha S, Thiyagarajan V, Huang HC, Hseu YC. Antrodia salmonea induces apoptosis and enhances cytoprotective autophagy in colon cancer cells Aging (Albany NY). 2021 May 24;13(12):15964-15989.
  • Suzuki H, Sozen T, Hasegawa Y, Chen W, Zhang JH. Caspase-1 inhibitor prevents neurogenic pulmonary edema after subarachnoid hemorrhage in mice Stroke. 2009 Dec;40(12):3872-5.
  • Halder SK, Matsunaga H, Ueda H. Neuron-specific non-classical release of prothymosin alpha: a novel neuroprotective damage-associated molecular patterns J Neurochem. 2012 Oct;123(2):262-75.
  • Okuda T, Sugahara K, Takemoto T, Shimogori H, Yamashita H. Inhibition of caspases alleviates gentamicin-induced cochlear damage in guinea pigs Auris Nasus Larynx. 2005 Mar;32(1):33-7.
  • Supinski GS, Callahan LA. Caspase activation contributes to endotoxin-induced diaphragm weakness J Appl Physiol (1985). 2006 Jun;100(6):1770-7.

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    Product Use & Eligibility
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Product Resources:

Manual Manual
Brochure Brochure

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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