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Protein Tyrosine Phosphatase 1B Substrate - (5-FAM) labeled Proteins Molecular Depot
Protein Tyrosine Phosphatase 1B Substrate - (5-FAM) labeled Proteins Molecular Depot
Protein Tyrosine Phosphatase 1B Substrate - (5-FAM) labeled Proteins Molecular Depot
Protein Tyrosine Phosphatase 1B Substrate - (5-FAM) labeled Proteins Molecular Depot

Protein Tyrosine Phosphatase 1B Substrate - (5-FAM) labeled

$795.00

    Catalog Number: B2019450 (1 mg)

    Protein Tyrosine Phosphatase 1B (PTP1B) is an enzyme that regulates cellular processes by dephosphorylating tyrosine residues on proteins. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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What's Included

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VR Headset

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2 Touch Controllers

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Charging Cable

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Power Adapter

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Protein Tyrosine Phosphatase 1B Substrate - (5-FAM) labeled

Catalog number: B2019450
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: 1691.6
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: -20°C
Keywords: 5-FAM-ELEF-pY-MDYE-NH2
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References

  • Feng T, Yan S, Hou S, Fan X. Novel fluorescence biosensor custom-made for protein tyrosine phosphatase 1B detection based on titanium dioxide-decorated single-walled carbon nanohorn nanocomposite Spectrochim Acta A Mol Biomol Spectrosc. 2022 Nov 5;280:121548.
  • González Wusener AE, González Á, Perez Collado ME, Maza MR, General IJ, Arregui CO. Protein tyrosine phosphatase 1B targets focal adhesion kinase and paxillin in cell-matrix adhesions J Cell Sci. 2021 Oct 15;134(20):jcs258769.
  • Durgannavar T, Kwon SJ, Ghisaidoobe ABT, Rho K, Kim JH, Yoon SY, Kang HJ, Chung SJ. Label-Free Detection of Protein Tyrosine Phosphatase 1B (PTP1B) by Using a Rationally Designed Förster Resonance Energy Transfer (FRET) Probe Chembiochem. 2018 Dec 4;19(23):2495-2501.
  • Romsicki Y, Reece M, Gauthier JY, Asante-Appiah E, Kennedy BP. Protein tyrosine phosphatase-1B dephosphorylation of the insulin receptor occurs in a perinuclear endosome compartment in human embryonic kidney 293 cells J Biol Chem. 2004 Mar 26;279(13):12868-75.
  • Monteleone MC, González Wusener AE, Burdisso JE, Conde C, Cáceres A, Arregui CO. ER-bound protein tyrosine phosphatase PTP1B interacts with Src at the plasma membrane/substrate interface PLoS One. 2012;7(6):e38948.
  • Martínez-Aldino IY, Villaseca-Murillo M, Morales-Jiménez J, Rivera-Chávez J. Absolute configuration and protein tyrosine phosphatase 1B inhibitory activity of xanthoepocin, a dimeric naphtopyrone from Penicillium sp. IQ-429 Bioorg Chem. 2021 Oct;115:105166.
  • Dadke S, Cotteret S, Yip SC, Jaffer ZM, Haj F, Ivanov A, Rauscher F 3rd, Shuai K, Ng T, Neel BG, Chernoff J. Regulation of protein tyrosine phosphatase 1B by sumoylation Nat Cell Biol. 2007 Jan;9(1):80-5.
  • Davis OB, Bishop AC. Specific inhibition of sensitized protein tyrosine phosphatase 1B (PTP1B) with a biarsenical probe Bioconjug Chem. 2012 Feb 15;23(2):272-8.
  • Li Y, Sun S, Tian X, Qiu JG, Jiang B, Wang LJ, Zhang CY. Dephosphorylation-directed tricyclic DNA amplification cascades for sensitive detection of protein tyrosine phosphatase Chem Commun (Camb). 2020 Oct 1;56(78):11581-11584.

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Product Resources:

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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