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PAMP-12 (Human) Chemicals Molecular Depot
PAMP-12 (Human) Chemicals Molecular Depot
PAMP-12 (Human) Chemicals Molecular Depot
PAMP-12 (Human) Chemicals Molecular Depot

PAMP-12 (Human)

$595.00

    Catalog Number: MDP0710 (500 ug)

    PAMP-12 (Human) is a high quality PAMP-12 (Human). This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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    Email: info@bluetigerscientific.com

    Text/SMS: (833) 928-4437 Mon–Fri, (8 am – 8 pm PST)

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Manufacturer Warranty

All products are covered by manufacturer warranty

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What's Included

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VR Headset

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2 Touch Controllers

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Charging Cable

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Power Adapter

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Glasses Spacer

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PAMP-12 (Human)

Catalog number: MDP0710
CAS Number: N/A
Sequence: Phe-Arg-Lys-Lys-Trp-Asn-Lys-Trp-Ala-Leu-Ser-Arg-NH2
Amount: 500 ug
Molecular Weight: 1618.8 g/mol
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: -20 °C
WARNING: For in vitro Research Use Only. NOT for use on humans or animals.
Grade: Biotechnology grade. All products are highly pure.

References

  • Chen E, Chuang LS, Giri M, Villaverde N, Hsu NY, Sabic K, Joshowitz S, Gettler K, Nayar S, Chai Z, Alter IL, Chasteau CC, Korie UM, Dzedzik S, Thin TH, Jain A, Moscati A, Bongers G, Duerr RH, Silverberg MS, Brant SR, Rioux JD, Peter I, Schumm LP, Haritunians T, McGovern DP, Itan Y, Cho JH. Inflamed Ulcerative Colitis Regions Associated With MRGPRX2-Mediated Mast Cell Degranulation and Cell Activation Modules, Defining a New Therapeutic Target Gastroenterology. 2021 Apr;160(5):1709-1724.
  • Bawazir M, Amponnawarat A, Hui Y, Oskeritzian CA, Ali H. Inhibition of MRGPRX2 but not FcεRI or MrgprB2-mediated mast cell degranulation by a small molecule inverse receptor agonist Front Immunol. 2022 Oct 6;13:1033794.
  • Belloni AS, Rossi GP, Andreis PG, Aragona F, Champion HC, Kadowitz PJ, Murphy WA, Coy DH, Nussdorfer GG. Proadrenomedullin N-terminal 20 peptide (PAMP), acting through PAMP(12-20)-sensitive receptors, inhibits Ca2+-dependent, agonist-stimulated secretion of human adrenal glands Hypertension. 1999 May;33(5):1185-9.
  • Fry RC, Champion HC, Lawrence TC, Murphy WA, Coy DH, Kadowitz PJ. Proadrenomedullin NH2-terminal peptide (PAMP)(12-20) has vasodepressor activity in the rat and cat Life Sci. 1997;60(10):PL161-7.
  • Lu L, Parmar MB, Kulka M, Kwan P, Unsworth LD. Self-Assembling Peptide Nanoscaffold That Activates Human Mast Cells ACS Appl Mater Interfaces. 2018 Feb 21;10(7):6107-6117.
  • Nussdorfer GG. Proadrenomedullin-derived peptides in the paracrine control of the hypothalamo-pituitary-adrenal axis Int Rev Cytol. 2001;206:249-84.
  • Kamohara M, Matsuo A, Takasaki J, Kohda M, Matsumoto M, Matsumoto S, Soga T, Hiyama H, Kobori M, Katou M. Identification of MrgX2 as a human G-protein-coupled receptor for proadrenomedullin N-terminal peptides Biochem Biophys Res Commun. 2005 May 20;330(4):1146-52.
  • Kuwasako K, Kitamura K, Kangawa K, Ishiyama Y, Kato J, Eto T. Increased plasma proadrenomedullin N-terminal 20 peptide in patients with essential hypertension Ann Clin Biochem. 1999 Sep;36 ( Pt 5):622-8.
  • Raj S, Lu L, Unsworth LD. Screening Peptides that Activate MRGPRX2 using Engineered HEK Cells J Vis Exp. 2021 Nov 6;(177).

    Terms & Conditions

    Blue Tiger Scientific is an independent third-party distributor of select products manufactured by Molecular Depot LLC. By purchasing from bluetigerscientific.com, you (“the Customer”) agree to the following terms, adapted from Molecular Depot’s original conditions:

    Product Use & Eligibility
    Products are for in vitro research use only (RUO). They are not intended for human or animal use, diagnosis, therapy, resale to consumers, or residential delivery. Sales are limited to verified business addresses.

    Payment Terms
    All purchases are prepaid and non-refundable once confirmed. Pricing is in USD and subject to change without notice.

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    Quality System (MD Levels)
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    MD 1000: Non-regulated use, no change notification

    MD 2000: Non-regulated use, limited change notification

    MD 3000: Regulated use, enhanced quality standards

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Product Resources:

Manual Manual
Brochure Brochure

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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