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Insulin I (Rat, Mouse) Chemicals Molecular Depot
Insulin I (Rat, Mouse) Chemicals Molecular Depot

Insulin I (Rat, Mouse)

$907.00

    Catalog Number: MDP0851 (50 μg)

    Insulin I (Rat, Mouse) is a synthetic peptide consisting of Insulin I (Rat, Mouse). This product is highly pure and has a MW of 5803.6 g/mol. This product is for in vitro research use only and is not human or animal use. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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Insulin I (Rat, Mouse)

Catalog # MDP0851
CAS # 91841-27-9
Amount 50 μg
Molecular Weight 5803.6 g/mol
Sequence A-chain: Gly-Ile-Val-Asp-Gln-Cys-Cys-Thr-Ser-Ile-Cys-Ser-Leu-Tyr-Gln-Leu-Glu-Asn-Tyr-Cys-Asn
B-chain: Phe-Val-Lys-Gln-His-Leu-Cys-Gly-Pro-His-Leu-Val-Glu-Ala-Leu-Tyr-Leu-Val-Cys-Gly-Glu-Arg-Gly-Phe-Phe-Tyr-Thr-Pro-Lys-Ser
Disulfide bonds: CysA6–CysA11, CysA7–CysB7, CysA20–CysB19
Supplied as Powder
Storage -20°C
Applications Molecular tool for biochemical research
Grade Biotechnology grade

Insulin I (Rat, Mouse) is a biotechnology-grade peptide designed for in vitro research applications. This dual-chain insulin analog features a well-defined amino acid sequence and three disulfide bonds essential for structural integrity. With a molecular weight of 5803.6 g/mol, it is widely used to study insulin secretion, receptor binding, and endocrine signaling in rodent models.

The product is supplied as a 50 μg powder aliquot and should be stored at -20°C. It is particularly useful for comparative studies of insulin physiology between rats and mice, as supported by extensive literature. All components are highly pure and compliant with RUO standards—this product is not intended for human or animal use.

Key benefits:

  • Biotechnology-grade purity for reproducible in vitro assays
  • Includes full A- and B-chain sequences with annotated disulfide bonding
  • Validated in over 10 peer-reviewed studies
  • Stable at -20°C; powder format for flexible reconstitution
  • RUO-compliant: not for clinical or veterinary use

Indication for Use:
This product is for Research Use Only (RUO). It is not intended for human or animal use, diagnostic procedures, or therapeutic applications.

References:

  • Furman BL. Streptozotocin-Induced Diabetic Models in Mice and Rats. Curr Protoc. 2021 Apr;1(4):e78.
  • Ma YH et al. Differences in insulin secretion between the rat and mouse: role of cAMP. Eur J Endocrinol. 1995 Mar;132(3):370-6.
  • Wentworth BM et al. Ratio of mouse insulin I:II vs preproinsulin mRNAs. Mol Cell Endocrinol. 1992 Aug;86(3):177-86.
  • Ahrén B. ANF inhibits glucose-stimulated insulin secretion. Am J Physiol. 1988 Nov;255(5 Pt 1):E579-82.
  • Pettersson M et al. CGRP in pancreatic islets and insulin inhibition. Endocrinology. 1986 Aug;119(2):865-9.
  • Maechler P et al. Glutamate and insulin secretion kinetics. Diabetes. 2002 Feb;51 Suppl 1:S99-102.
  • Lenzen S. Insulin secretion by perfused pancreas. Am J Physiol. 1979 Apr;236(4):E391-400.
  • Birch NP et al. Immunoreactive insulin in brain cultures. Biochem J. 1984 Feb 15;218(1):19-27.
  • Hepatotrophic factors. Lancet. 1978 Jul 29;2(8083):244-5.
  • Carlsson A et al. ELISA of rat insulin, C-peptide, and proinsulin. Endocrinology. 2010 Oct;151(10):5048-52.

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Product Resources:

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Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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