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Hyaluronic Acid Binding Protein (Bovine) Proteins Molecular Depot
Hyaluronic Acid Binding Protein (Bovine) Proteins Molecular Depot
Hyaluronic Acid Binding Protein (Bovine) Proteins Molecular Depot
Hyaluronic Acid Binding Protein (Bovine) Proteins Molecular Depot

Hyaluronic Acid Binding Protein (Bovine)

$813.00

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Hyaluronic Acid Binding Protein (Bovine)

Catalog number: P2010012
Lot number: Batch Dependent
Expiration date: Batch Dependent
Package Size: 50 µg
Synonyms: HABP, hyaladherin
Source: Bovine Nasal Cartilage
Concentration: 1000 µg/mL
Purity: Affinity purified
Specificity: Binds to hyaluronic acid (≥2000 M.W.)
Buffer: PBS1X
Storage: -20°C or lower. Avoid repeated freeze-thaw.

Hyaluronic Acid Binding Protein (HABP) is a highly purified glycoprotein isolated from bovine nasal cartilage, known for its strong and specific affinity to hyaluronic acid polymers ≥2000 M.W. This reagent is essential for studying extracellular matrix interactions, cell adhesion, and hyaluronan-mediated signaling. Supplied at 1000 µg/mL in PBS1X, it is affinity purified to ensure high specificity and reproducibility in biochemical and cell-based assays.

HABP is widely used in histological staining, ELISA development, and receptor-ligand binding studies involving CD44 and other hyaladherin pathways. Its ability to selectively bind hyaluronic acid makes it a valuable tool for investigating tissue remodeling, inflammation, and cancer biology. All components are biotechnology grade and filtered through 0.22 µm membranes using Type I ultrapure water (resistivity >18 MΩ·cm).

Key Features:

  • Affinity-purified HABP from bovine nasal cartilage
  • Specific binding to hyaluronic acid polymers ≥2000 M.W.
  • Validated for use in ELISA, histology, and cell signaling assays
  • Supplied in PBS1X at 1000 µg/mL for ready-to-use convenience
  • RUO designation: not for clinical or therapeutic applications

Indication for Use:
This product is for Research Use Only. It is not intended for human or animal use, diagnostic procedures, or therapeutic applications.

References Related to Hyaluronic Acid Binding Protein from Bovine Nasal Cartilage

  • Deb TB, Datta K. Molecular cloning of human fibroblast hyaluronic acid-binding protein confirms its identity with P-32, a protein co-purified with splicing factor SF2. J Biol Chem. 1996 Jan 26;271(4):2206-12.
  • Bartheldyová E et al. Hyaluronic Acid Surface Modified Liposomes Prepared via Orthogonal Aminoxy Coupling: Synthesis of Nontoxic Aminoxylipids Based on Symmetrically α-Branched Fatty Acids, Preparation of Liposomes by Microfluidic Mixing, and Targeting to Cancer Cells Expressing CD44. Bioconjug Chem. 2018 Jul 18;29(7):2343-2356.
  • Yoshino Y, Goto M, Hara H, Inoue S. The role and regulation of TMEM2 in HYBID-mediated HA depolymerization in human skin fibroblasts. Biochem Biophys Res Commun. 2018 Oct 20;505(1):74-80.
  • Freeman SA et al. Transmembrane Pickets Connect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement. Cell. 2018 Jan 11;172(1-2):305-317.e10.
  • Muterspaugh R et al. Interaction of Insulin-Like Growth Factor-Binding Protein 3 With Hyaluronan and Its Regulation by Humanin and CD44. Biochemistry. 2018 Oct 2;57(39):5726-5737.

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Product Resources:

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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