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Human AKR1C1 Protein (Highly Pure) Proteins Molecular Depot
Human AKR1C1 Protein (Highly Pure) Proteins Molecular Depot
Human AKR1C1 Protein (Highly Pure) Proteins Molecular Depot
Human AKR1C1 Protein (Highly Pure) Proteins Molecular Depot

Human AKR1C1 Protein (Highly Pure)

$907.00

    Catalog Number: B2011564 (100 µg)

    Human AKR1C1 Protein (Highly Pure) is a high quality recombinant human AKR1C1 protein His tagged and expressed in E. coli. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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What's Included

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VR Headset

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2 Touch Controllers

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Charging Cable

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Power Adapter

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Glasses Spacer

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Human AKR1C1 Protein (Highly Pure)

Catalog number: B2011564
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 µg
Molecular Weight or Concentration: 0.5 mg/mL
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: AKRC 1, Aldo keto reductase family 1 member C1 protein, AKRC-1, DDH protein, Chlordecone reductase homolog protein, Dihydrodiol dehydrogenase 1 protein, Chlordecone reductase homolog HAKRC protein, , DD1/DD2 protein, AK1C1 protein, C9 protein, 2 diol dehydrogenase protein, AKRC 1 protein, MBAB protein, Trans-1 protein, HAKRC protein, DDH1 protein, 20 alpha hydroxysteroid dehydrogenase protein, HBAB protein, member C1 20 alpha (3 alpha) hydroxysteroid dehydrogenase protein, 20-alpha-HSD protein, AKRC-1 protein, 2 dihydrobenzene 1 protein, DD1 protein, 2ALPHAHSD protein, Aldo-keto reductase family 1 protein, H37 protein, High affinity hepatic bile acid-binding protein , Hepatic dihydrodiol dehydrogenase protein, AKR1C1, Dihydrodiol dehydrogenase 1/2 protein, Type II 3 alpha hydroxysteroid dehydrogenase protein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References

  • Shi Y, Fan S, Wu M, Zuo Z, Li X, Jiang L, Shen Q, Xu P, Zeng L, Zhou Y, Huang Y, Yang Z, Zhou J, Gao J, Zhou H, Xu S, Ji H, Shi P, Wu DD, Yang C, Chen Y. YTHDF1 links hypoxia adaptation and non-small cell lung cancer progression Nat Commun. 2019 Oct 25;10(1):4892.
  • Penning TM. The aldo-keto reductases (AKRs): Overview Chem Biol Interact. 2015 Jun 5;234:236-46.
  • Wohlhieter CA, Richards AL, Uddin F, Hulton CH, Quintanal-Villalonga À, Martin A, de Stanchina E, Bhanot U, Asher M, Shah NS, Hayatt O, Buonocore DJ, Rekhtman N, Shen R, Arbour KC, Donoghue M, Poirier JT, Sen T, Rudin CM. Concurrent Mutations in STK11 and KEAP1 Promote Ferroptosis Protection and SCD1 Dependence in Lung Cancer Cell Rep. 2020 Dec 1;33(9):108444.
  • El-Kabbani O, Dhagat U, Hara A. Inhibitors of human 20α-hydroxysteroid dehydrogenase (AKR1C1) J Steroid Biochem Mol Biol. 2011 May;125(1-2):105-11.
  • Li K, Ding S, Chen K, Qin D, Qu J, Wang S, Sheng Y, Zou C, Chen L, Tang H. Hepatitis B Virus X Protein Up-Regulates AKR1C1 Expression Through Nuclear Factor-Y in Human Hepatocarcinoma Cells Hepat Mon. 2013 May 27;13(5):e8792.
  • Chu X, He S, Liu Y, Liu Y, Feng F, Guo Q, Zhao L, Sun H. Overview of human 20 alpha-hydroxysteroid dehydrogenase (AKR1C1): Functions, regulation, and structural insights of inhibitors Chem Biol Interact. 2022 Jan 5;351:109746.
  • Gagliardi M, Cotella D, Santoro C, Corà D, Barlev NA, Piacentini M, Corazzari M. Aldo-keto reductases protect metastatic melanoma from ER stress-independent ferroptosis Cell Death Dis. 2019 Nov 28;10(12):902.
  • Beranič N, Gobec S, Rižner TL. Progestins as inhibitors of the human 20-ketosteroid reductases, AKR1C1 and AKR1C3 Chem Biol Interact. 2011 May 30;191(1-3):227-33.
  • Gao Y, Xu D, Li H, Xu J, Pan Y, Liao X, Qian J, Hu Y, Yu G. Avasimibe Dampens Cholangiocarcinoma Progression by Inhibiting FoxM1-AKR1C1 Signaling Front Oncol. 2021 May 28;11:677678.

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    Blue Tiger Scientific is an independent third-party distributor of select products manufactured by Molecular Depot LLC. By purchasing from bluetigerscientific.com, you (“the Customer”) agree to the following terms, adapted from Molecular Depot’s original conditions:

    Product Use & Eligibility
    Products are for in vitro research use only (RUO). They are not intended for human or animal use, diagnosis, therapy, resale to consumers, or residential delivery. Sales are limited to verified business addresses.

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Product Resources:

Manual Manual
Brochure Brochure

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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