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ERK 1/2 /MAP Kinase Substrate - (5-FAM) labeled Peptides Molecular Depot
ERK 1/2 /MAP Kinase Substrate - (5-FAM) labeled Peptides Molecular Depot
ERK 1/2 /MAP Kinase Substrate - (5-FAM) labeled Peptides Molecular Depot
ERK 1/2 /MAP Kinase Substrate - (5-FAM) labeled Peptides Molecular Depot

ERK 1/2 /MAP Kinase Substrate - (5-FAM) labeled

$795.00

    Catalog Number: B2019457 (1 mg)

    ERK 1/2, or Extracellular signal-Regulated Kinases 1 and 2, are part of the MAPK signaling pathway, crucial for cellular processes like growth and differentiation. It is labeled with a fluorescent dye, allowing for detection and quantification in various assays. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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What's Included

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VR Headset

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2 Touch Controllers

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Charging Cable

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Power Adapter

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Glasses Spacer

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ERK 1/2 /MAP Kinase Substrate - (5-FAM) labeled

Catalog number: B2019457
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: 2277.6
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: -20°C
Keywords: 5-FAM-IPTSPITTTYFFFKKK
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References

  • Wang Q, Downey GP, Herrera-Abreu MT, Kapus A, McCulloch CA. SHP-2 modulates interleukin-1-induced Ca2+ flux and ERK activation via phosphorylation of phospholipase Cgamma1 J Biol Chem. 2005 Mar 4;280(9):8397-406.
  • Ram A, Edwards TM, McCarty A, McDermott MV, Bobeck EN. Morphine-induced kinase activation and localization in the periaqueductal gray of male and female mice J Neurochem. 2021 Nov;159(3):590-602.
  • Oncel S, Basson MD. ZINC40099027 promotes monolayer circular defect closure by a novel pathway involving cytosolic activation of focal adhesion kinase and downstream paxillin and ERK1/2 Cell Tissue Res. 2022 Nov;390(2):261-279.
  • Xie Y, Potter CMF, Le Bras A, Nowak WN, Gu W, Bhaloo SI, Zhang Z, Hu Y, Zhang L, Xu Q. Leptin Induces Sca-1(+) Progenitor Cell Migration Enhancing Neointimal Lesions in Vessel-Injury Mouse Models Arterioscler Thromb Vasc Biol. 2017 Nov;37(11):2114-2127.
  • Whitehurst A, Cobb MH, White MA. Stimulus-coupled spatial restriction of extracellular signal-regulated kinase 1/2 activity contributes to the specificity of signal-response pathways Mol Cell Biol. 2004 Dec;24(23):10145-50.
  • Iordanov M, Bender K, Ade T, Schmid W, Sachsenmaier C, Engel K, Gaestel M, Rahmsdorf HJ, Herrlich P. CREB is activated by UVC through a p38/HOG-1-dependent protein kinase EMBO J. 1997 Mar 3;16(5):1009-22.
  • Zhang R, Liu S, Guo B, Chang L, Li Y. Chemerin induces insulin resistance in rat cardiomyocytes in part through the ERK1/2 signaling pathway Pharmacology. 2014;94(5-6):259-64.
  • Huynh H, Chow PK, Soo KC. AZD6244 and doxorubicin induce growth suppression and apoptosis in mouse models of hepatocellular carcinoma Mol Cancer Ther. 2007 Sep;6(9):2468-76.
  • Dimitri CA, Dowdle W, MacKeigan JP, Blenis J, Murphy LO. Spatially separate docking sites on ERK2 regulate distinct signaling events in vivo Curr Biol. 2005 Jul 26;15(14):1319-24.

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Product Resources:

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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