β-Endorphin (Human) – Catalog Number: MDP0410 (500 µg)

β-Endorphin (Human) is a potent endogenous opioid peptide derived from the N-terminal region of pro-opiomelanocortin (POMC), supplied here as a lyophilized 500 µg powder (Catalog MDP0410). Its precise amino acid sequence—Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-Tyr-Lys-Lys-Gly-Glu—and molecular weight (~3464.8 g/mol) make it ideal for analytical and functional studies of opioid receptor activity. Storage at −20 °C ensures peptide integrity and long-term stability, while high biotechnology-grade purity enhances sensitivity and consistency in demanding research contexts.

In neuroscience and pharmacology research, β-Endorphin (Human) serves as a critical reference peptide for receptor binding assays, signaling pathway characterization, and mass spectrometry calibration. It’s widely used in studies of pain modulation, stress response, and neurochemical feedback mechanisms. The well-defined sequence and purity profile also support ELISA standard curves, HPLC/MS quantitation, and behavioral neurochemistry experiments. Because the peptide is active at nanomolar concentrations, careful reconstitution—often using acidified buffer (e.g., 0.1% TFA)—is advised to maintain solubility and minimize aggregation.

Research workflows benefit from pilot dosing to establish appropriate assay concentrations, particularly when working with receptor-expressing systems or neuroendocrine models. Documentation-ready fields like amount, sequence, molecular weight, and storage conditions support SOP compliance and LIMS integration, enabling reliable reproducibility across labs. Within research-only boundaries, β-Endorphin (Human) is a documentation-friendly tool that advances investigations into opioid biology and peptide neuroscience with precision and confidence.

Why researchers choose this product:

• Precise native human β-Endorphin sequence for receptor pharmacology and neurochemical assays
• High purity powder (biotechnology grade) enhances assay sensitivity and reproducibility
• Well-defined molecular weight (~3464.8 g/mol) and sequence facilitate quantitation and validation
• Compact 500 µg fill balances experimental flexibility with extended usability
• Storage at −20 °C ensures peptide stability over repeated use

WARNING: For in vitro Research Use Only. NOT for use on humans or animals.

References

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