DIC (N,N′-diisopropylcarbodiimide) – Catalog Number: B2015766 (5 mL)

DIC (N,N′-diisopropylcarbodiimide) is supplied as a biotechnology-grade solution in a defined 5 mL fill (Catalog B2015766) with storage at RT. The supplier identifies this reagent as a high-quality carbodiimide used as a coupling reagent in the synthesis of amides, peptides, ureas, heterocycles, and unsymmetrical carbodiimides. It is also noted as a molecular tool for various biochemical applications and has been used in a wide array of other chemical and immunological workflows. These concise, documentation-friendly fields—amount, supplied-as, storage, keyword identity, and a biotechnology-grade statement—support straightforward SOP inclusion and inventory traceability for multi-user labs.

In research practice, carbodiimide coupling reagents are valued for activating carboxyl groups toward bond formation with nucleophiles under mild conditions. A liquid presentation allows direct volumetric dosing and rapid compatibility checks with intended solvent systems. Because no working concentration or protocol is prescribed on the listing, good bench practice is to determine conditions empirically for the matrix and functional groups at hand. Pilot titrations that vary reagent equivalents, solvent composition, and temperature, with careful documentation of times and quench/cleanup steps, help establish a reliable operating window. Recording lot identifiers and time-at-temperature provides reproducibility across operators and batches and simplifies transfer into formal SOPs.

Typical use-cases include assembling qualitative coupling controls for method development, drafting training exercises that demonstrate carbodiimide-mediated activation, and running small-scale screens to compare coupling strategies in peptide or urea formation. The supplier’s emphasis on broad applicability across chemical, biochemical, and immunological contexts aligns with these scenarios, and the ready-to-use solution format integrates easily into benchtop workflows. Within research-only boundaries, this DIC offering provides a clearly specified, dependable component for laboratories standardizing carbodiimide-based coupling and exploratory synthesis.

Why researchers choose this product:

• Identified by the supplier as a coupling reagent for amides, peptides, ureas, heterocycles, and unsymmetrical carbodiimides
• Ready-to-use solution format in a defined 5 mL fill supports quick method setup
• Listed use across biochemical, chemical, and immunological workflows
• Specified RT storage simplifies routine handling and inventory
• Biotechnology-grade note supports low-background expectations during optimization

This product is for Research Use Only (RUO). It is not intended for diagnostic or therapeutic use.

References

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