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Bak BH3 - TAMRA labeled Peptides Molecular Depot
Bak BH3 - TAMRA labeled Peptides Molecular Depot
Bak BH3 - TAMRA labeled Peptides Molecular Depot
Bak BH3 - TAMRA labeled Peptides Molecular Depot

Bak BH3 - TAMRA labeled

$1,167.00

    Catalog Number: B2019440 (1 mg)

    Bak BH3 – TAMRA labeled is a peptide used in biochemical research, particularly in studies of apoptosis and protein interactions. It consists of Bak, a pro-apoptotic protein, the BH3 domain for protein interactions, and TAMRA, a fluorescent dye for tracking peptides in biological systems. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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    Email: info@bluetigerscientific.com

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What's Included

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VR Headset

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2 Touch Controllers

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Charging Cable

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Power Adapter

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Glasses Spacer

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Bak BH3 - TAMRA labeled

Catalog number: B2019440
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: 2265.6
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: -20°C
Keywords: GQVGRQLAIIGDDINR-K(TAMRA)-NH2
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References

  • Wang Y, Su W, Mai Z, Yu S, Wang X, Chen T. Anti-apoptotic capacity of Mcl-1Δ127 Biochem Biophys Res Commun. 2020 Jun 11;526(4):1042-1048.
  • Wang Y, Su W, Mai Z, Du M, Yu S, Liu Y, Wang X, Chen T. Co-expression of Mcl-1 and Bak induces mitochondrial swelling Biochem Biophys Res Commun. 2020 Jul 5;527(4):866-873.
  • Kazi A, Sun J, Doi K, Sung SS, Takahashi Y, Yin H, Rodriguez JM, Becerril J, Berndt N, Hamilton AD, Wang HG, Sebti SM. The BH3 alpha-helical mimic BH3-M6 disrupts Bcl-X(L), Bcl-2, and MCL-1 protein-protein interactions with Bax, Bak, Bad, or Bim and induces apoptosis in a Bax- and Bim-dependent manner J Biol Chem. 2011 Mar 18;286(11):9382-92.
  • Vela L, Gonzalo O, Naval J, Marzo I. Direct interaction of Bax and Bak proteins with Bcl-2 homology domain 3 (BH3)-only proteins in living cells revealed by fluorescence complementation J Biol Chem. 2013 Feb 15;288(7):4935-46.
  • Lin N, Zheng W, Li L, Liu H, Wang T, Wang P, Ma X. A novel system enhancing the endosomal escapes of peptides promotes Bak BH3 peptide inducing apoptosis in lung cancer A549 cells Target Oncol. 2014 Jun;9(2):163-70.
  • Panaretakis T, Pokrovskaja K, Shoshan MC, Grandér D. Activation of Bak, Bax, and BH3-only proteins in the apoptotic response to doxorubicin J Biol Chem. 2002 Nov 15;277(46):44317-26.
  • Zhang Z, Song T, Zhang T, Gao J, Wu G, An L, Du G. A novel BH3 mimetic S1 potently induces Bax/Bak-dependent apoptosis by targeting both Bcl-2 and Mcl-1 Int J Cancer. 2011 Apr 1;128(7):1724-35.
  • Zhang J, Huang K, O’Neill KL, Pang X, Luo X. Bax/Bak activation in the absence of Bid, Bim, Puma, and p53 Cell Death Dis. 2016 Jun 16;7(6):e2266.
  • Gonzalo Ó, Benedi A, Vela L, Anel A, Naval J, Marzo I. Study of the Bcl-2 Interactome by BiFC Reveals Differences in the Activation Mechanism of Bax and Bak Cells. 2023 Mar 3;12(5):800.

    Terms & Conditions

    Blue Tiger Scientific is an independent third-party distributor of select products manufactured by Molecular Depot LLC. By purchasing from bluetigerscientific.com, you (“the Customer”) agree to the following terms, adapted from Molecular Depot’s original conditions:

    Product Use & Eligibility
    Products are for in vitro research use only (RUO). They are not intended for human or animal use, diagnosis, therapy, resale to consumers, or residential delivery. Sales are limited to verified business addresses.

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    All purchases are prepaid and non-refundable once confirmed. Pricing is in USD and subject to change without notice.

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    Blue Tiger Scientific and Molecular Depot LLC are not responsible for any damages resulting from product use or misuse.

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    By ordering, you waive all claims arising from use of Molecular Depot products.

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    MD 1000: Non-regulated use, no change notification

    MD 2000: Non-regulated use, limited change notification

    MD 3000: Regulated use, enhanced quality standards

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Product Resources:

Manual Manual
Brochure Brochure

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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