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APETx2 Chemicals Molecular Depot
APETx2 Chemicals Molecular Depot
APETx2 Chemicals Molecular Depot
APETx2 Chemicals Molecular Depot

APETx2

$907.00

    Catalog Number: MDP0826 (100 ug)

    APETx2 is a high quality APETx2. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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    Email: info@bluetigerscientific.com

    Text/SMS: (833) 928-4437 Mon–Fri, (8 am – 8 pm PST)

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All products are covered by manufacturer warranty

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What's Included

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VR Headset

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2 Touch Controllers

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Charging Cable

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Power Adapter

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Glasses Spacer

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APETx2

Catalog number: MDP0826
CAS Number: 1678415-52-5
Sequence: Gly-Thr-Ala-Cys-Ser-Cys-Gly-Asn-Ser-Lys-Gly-Ile-Tyr-Trp-Phe-Tyr-Arg-Pro-Ser-Cys-Pro-Thr-Asp-Arg-Gly-Tyr-Thr-Gly-Ser-Cys-Arg-Tyr-Phe-Leu-Gly-Thr-Cys-Cys-Thr-Pro-Ala-Asp (Reported disulfide bonds between Cys4-Cys37, Cys6-Cys30, Cys20-Cys38)
Amount: 100 ug
Molecular Weight: 4560.8 g/mol
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: -20 °C
WARNING: For in vitro Research Use Only. NOT for use on humans or animals.
Grade: Biotechnology grade. All products are highly pure.

References

  • Bian J, Cai F, Chen H, Tang Z, Xi K, Tang J, Wu L, Xu Y, Deng L, Gu Y, Cui W, Chen L. Modulation of Local Overactive Inflammation via Injectable Hydrogel Microspheres Nano Lett. 2021 Mar 24;21(6):2690-2698.
  • Yuan L, Xiao H, Li H, Yan B. APETx2 regulates intestinal motility and visceral sensitivity in post-infectious irritable bowel syndrome mice through 5-HT signalling pathway J Pharm Pharmacol. 2023 Apr 17;75(5):712-717.
  • Yen LT, Hsieh CL, Hsu HC, Lin YW. Preventing the induction of acid saline-induced fibromyalgia pain in mice by electroacupuncture or APETx2 injection Acupunct Med. 2020 Jun;38(3):188-193.
  • Diochot S, Baron A, Rash LD, Deval E, Escoubas P, Scarzello S, Salinas M, Lazdunski M. A new sea anemone peptide, APETx2, inhibits ASIC3, a major acid-sensitive channel in sensory neurons EMBO J. 2004 Apr 7;23(7):1516-25.
  • Blanchard MG, Rash LD, Kellenberger S. Inhibition of voltage-gated Na(+) currents in sensory neurones by the sea anemone toxin APETx2 Br J Pharmacol. 2012 Apr;165(7):2167-77.
  • Lee JYP, Saez NJ, Cristofori-Armstrong B, Anangi R, King GF, Smith MT, Rash LD. Inhibition of acid-sensing ion channels by diminazene and APETx2 evoke partial and highly variable antihyperalgesia in a rat model of inflammatory pain Br J Pharmacol. 2018 Jun;175(12):2204-2218.
  • Karczewski J, Spencer RH, Garsky VM, Liang A, Leitl MD, Cato MJ, Cook SP, Kane S, Urban MO. Reversal of acid-induced and inflammatory pain by the selective ASIC3 inhibitor, APETx2 Br J Pharmacol. 2010 Oct;161(4):950-60.
  • Anangi R, Rash LD, Mobli M, King GF. Functional expression in Escherichia coli of the disulfide-rich sea anemone peptide APETx2, a potent blocker of acid-sensing ion channel 3 Mar Drugs. 2012 Jul;10(7):1605-1618.
  • Anangi R, Chen CC, Lin YW, Cheng YR, Cheng CH, Chen YC, Chu YP, Chuang WJ. Expression in Pichia pastoris and characterization of APETx2, a specific inhibitor of acid sensing ion channel 3 Toxicon. 2010 Dec;56(8):1388-97.

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    Blue Tiger Scientific is an independent third-party distributor of select products manufactured by Molecular Depot LLC. By purchasing from bluetigerscientific.com, you (“the Customer”) agree to the following terms, adapted from Molecular Depot’s original conditions:

    Product Use & Eligibility
    Products are for in vitro research use only (RUO). They are not intended for human or animal use, diagnosis, therapy, resale to consumers, or residential delivery. Sales are limited to verified business addresses.

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Product Resources:

Manual Manual
Brochure Brochure

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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