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β-ANP (Human) Chemicals Molecular Depot
β-ANP (Human) Chemicals Molecular Depot
β-ANP (Human) Chemicals Molecular Depot
β-ANP (Human) Chemicals Molecular Depot

β-ANP (Human)

$795.00

    Catalog Number: MDP0550 (100 ug)

    β-ANP (Human) is a high quality β-ANP (Human). This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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β-ANP (Human) – Catalog #MDP0550 (100 µg)

Catalog # MDP0550
Status Discontinued-Inquire
Amount 100 µg
Sequence Two-chain peptide: Ser-Leu-Arg-Arg-Ser-Ser-Cys₇-...-Cys₂₃-...-Tyr (interchain disulfide bonds))
Molecular Weight 6,160.8 g/mol
Supplied As Powder
Applications Biochemical and immunological research
Storage –20 °C
Grade Biotechnology grade; highly pure; prepared using Type I ultrapure water and 0.22 µm filtration

Disulfide-linked human atrial natriuretic peptide (β-ANP) featuring dual-chain structure for advanced cardiovascular signaling studies. β-ANP (Human) (Catalog #MDP0550) is a meticulously synthesized bi-peptide—comprising complementary A and B chains—designed to preserve native hormone-like activity. With precise formation of interchain disulfide bridges (CysA7–CysB23 and CysA23–CysB7) and a defined molecular mass (~6.16 kDa), this reagent reliably supports research in natriuretic peptide signaling, receptor affinity assays, and functional comparative studies with other ANP isoforms.

This compound, provided as a stable, lyophilized powder, allows easy dissolution and dosing for in vitro assays. It is ideally suited for exploring natriuretic receptor interactions, second messenger activation (cGMP pathways), and peptide metabolism across research domains including cardiology, nephrology, and endocrine regulation. This product is valued for its precise bioactivity and isoform specificity—serving as a reference standard in both academic and translational investigations.

Manufactured under strict biotech-grade protocols with high-purity reagents and sterile filtration, this peptide was stored at –20 °C to ensure integrity. Note: This product was intended exclusively for Research Use Only (RUO) and was never approved for diagnostic or therapeutic applications.

Key advantages:

  • Authentic β-ANP structure with correct dual-chain disulfide bonding
  • Reliable molecular performance for receptor and signaling studies
  • Stable powder format for consistent laboratory usage
  • Ideal for comparing function and bioactivity among ANP variants
  • Scalable quantities for extended research timelines

Indication for Use:
This product is for Research Use Only (RUO). It is not intended for diagnostic, therapeutic, or clinical use.

References:

  • Nakagawa Y, Nishikimi T, Kuwahara K. Atrial and brain natriuretic peptides: Hormones secreted from the heart Peptides. 2019 Jan;111:18-25.
  • Levin ER, Gardner DG, Samson WK. Natriuretic peptides N Engl J Med. 1998 Jul 30;339(5):321-8.
  • Richards AM, Nicholls MG, Espiner EA. Natriuretic peptides Clin Sci (Lond). 1995 Jan;88(1):18-21.
  • Sugawara A, Nakao K, Morii N, Yamada T, Itoh H, Shiono S, Saito Y, Mukoyama M, Arai H, Nishimura K, et al. Synthesis of atrial natriuretic polypeptide in human failing hearts. Evidence for altered processing of atrial natriuretic polypeptide precursor and augmented synthesis of beta-human ANP J Clin Invest. 1988 Jun;81(6):1962-70.
  • Itoh H, Nakao K, Sugawara A, Saito Y, Mukoyama M, Morii N, Yamada T, Shiono S, Arai H, Hosoda K, et al. Gamma-atrial natriuretic polypeptide (gamma ANP)-derived peptides in human plasma: cosecretion of N-terminal gamma ANP fragment and alpha ANP J Clin Endocrinol Metab. 1988 Sep;67(3):429-37.
  • Humphreys MH. Urodilatin–renal natriuretic peptide? J Am Soc Nephrol. 1991 Mar;1(9):1057-9.
  • Cannone V, Cabassi A, Volpi R, Burnett JC Jr. Atrial Natriuretic Peptide: A Molecular Target of Novel Therapeutic Approaches to Cardio-Metabolic Disease Int J Mol Sci. 2019 Jul 2;20(13):3265.
  • Wilkins MR, Redondo J, Brown LA. The natriuretic-peptide family Lancet. 1997 May 3;349(9061):1307-10.
  • Buckalew VM, Morris M, Hamilton RW. Atrial natriuretic factor Adv Intern Med. 1987;32:1-25.
  • Atrial natriuretic factor West J Med. 1986 May;144(5):591-5.

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Product Resources:

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Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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