Palmitic Acid (Highly Pure) – Catalog #B2015304 (1 g)

Biotechnology-grade palmitic acid for controlled exploration of lipid-mediated pathways in RUO contexts. Palmitic Acid (Highly Pure) (Catalog #B2015304, 1 g) is a saturated fatty acid constituting 20–30% of the human fatty acid profile. This high-purity, biotech-grade reagent is supplied as a stable powder and restored to room temperature upon reconstitution. It serves as a fundamental molecular tool across diverse biochemical applications—ranging from lipid signaling studies and membrane biophysics to inflammation research and metabolic profiling.

Because of its central role in cellular metabolism and inflammation, palmitic acid is extensively used in modeling insulin resistance, lipotoxicity, and immune activation pathways. Its well-characterized molecular weight and molecular identity ensure that experimental results are quantifiable and reproducible. The powder’s stability and room-temperature storage confer ease of handling in multi-user lab environments, while the high grade—strictly prepared using ultrapure water and microfiltration—reduces batch variability and background interference in sensitive assays.

Researchers studying metabolic disorders such as diabetes, non-alcoholic fatty liver disease, or neuroinflammation leverage palmitic acid to mimic physiological stress in vitro and ex vivo. It is also a standard compound for calibrating lipid quantification platforms and calibrators for chromatography methods. For long-term experimental workflows or high-throughput applications, custom bulk orders are available to support consistency and continuity. Palmitic Acid (Highly Pure) is a dependable foundation molecule for research-driven investigations into lipid biology.

Why researchers choose this product:

• Ultra-pure, biotech-grade reagent for predictable and reproducible results
• Common physiological fatty acid—widely relevant across lipid biology and metabolic models
• Stable powder form with RT storage for lab convenience and handling flexibility
• Ideal choice for metabolic, signaling, and lipid quantification assays
• Custom bulk options support workflow scaling and long-term project consistency

Indication for Use:
This product is for Research Use Only (RUO). It is not intended for diagnostic, therapeutic, or clinical purposes.

References:

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• 2: Sun Y, Wang J, Guo X, Zhu N, Niu L, Ding X, Xie Z, Chen X, Yang F. Oleic Acid and Eicosapentaenoic Acid Reverse Palmitic Acid-induced Insulin Resistance in Human HepG2 Cells via the Reactive Oxygen Species/JUN Pathway. Genomics Proteomics Bioinformatics. 2021 Oct;19(5):754-771.
• 3: Ashar Y, Teng Q, Wurpel JND, Chen ZS, Reznik SE. Palmitic Acid Impedes Extravillous Trophoblast Activity by Increasing MRP1 Expression and Function. Biomolecules. 2022 Aug 22;12(8):1162.
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• 5: van Rooijen MA, Mensink RP. Palmitic Acid Versus Stearic Acid: Effects of Interesterification and Intakes on Cardiometabolic Risk Markers – A Systematic Review. Nutrients. 2020 Feb 26;12(3):615.
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• 7: Urso CJ, Zhou H. Palmitic Acid Lipotoxicity in Microglia Cells Is Ameliorated by Unsaturated Fatty Acids. Int J Mol Sci. 2021 Aug 23;22(16):9093.
• 8: Tang W, Zhang M, Wang Y, Ma D, Hu M, Zhang Y, Lin H, Jiang W, Ouyang Y, Jiang L, He P, Zhao G. IGF-1 inhibits palmitic acid-induced mitochondrial apoptosis in macrophages. Mol Med Rep. 2023 Dec;28(6):234.