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Urea for Interference Testing (200 mg/mL solution) Chemicals Molecular Depot
Urea for Interference Testing (200 mg/mL solution) Chemicals Molecular Depot
Urea for Interference Testing (200 mg/mL solution) Chemicals Molecular Depot
Urea for Interference Testing (200 mg/mL solution) Chemicals Molecular Depot

Urea for Interference Testing (200 mg/mL solution)

$495.00

    Catalog #: K2010008U

    Urea for Interference Testing consists of a highly concentrated solution of Urea (200 mg/mL) provided with the corresponding diluent (diluent A). This solution can be spiked into specimens to test Urea interference and tolerance in assays. Custom bulk orders of this product are available upon request.

    Products are for in vitro research use only (RUO).

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Urea for Interference Testing (200 mg/mL solution)

Catalog number: K2010008U
Lot number: Batch Dependent
Expiration date: Batch Dependent
Content: • Urea 200 mg/mL in diluent A (1 mL)
Appearance: • Diluent A (2 mL)
Application: Clear Solution
Shelf-Life Interference Testing
Storage: 1 year
Keywords: At -20°C.

Urea for Interference Testing (200 mg/mL solution) is a high-purity reagent formulated to simulate uremic conditions in clinical assay validation workflows. Urea is a well-known interferent in immunoassays, particularly those involving enzymatic reactions, protein binding, or antibody-antigen interactions. This solution is prepared at a concentration of 200 mg/mL in Diluent A and supplied in a clear, ready-to-use format. It enables researchers and assay developers to evaluate the robustness, specificity, and accuracy of diagnostic platforms under physiologically relevant stress conditions.

Used extensively in interference testing protocols, this reagent supports the identification of assay vulnerabilities caused by elevated urea levels in patient samples. It is especially valuable in validating renal function panels, hormone assays, and therapeutic drug monitoring systems. The inclusion of Diluent A ensures compatibility with standard assay buffers, while the 1-year shelf life and storage at –20°C provide long-term reliability. Whether you're conducting EP07-compliant interference studies or troubleshooting unexpected signal drift, this reagent offers a consistent and reproducible matrix for high-confidence assay performance evaluation.

Key benefits:

  • 200 mg/mL urea solution for interference simulation in immunoassays

  • Supports EP07-compliant assay validation and robustness testing

  • Supplied in Diluent A for compatibility with standard assay buffers

  • Clear solution format for ease of use and reproducibility

  • Stable for 1 year when stored at –20°C

Products are for in vitro research use only (RUO).

References

  • Schiettecatte, J., Anckaert, E., and Smitz, J. (2012). Interferences in Immunoassays. Advances in Immunoassay Technology .
  • Miller, J. J., and Levinson, S. S. (1996). Interferences In Immunoassays. Immunoassay , 165–190.
  • Ward, G. (2013). Rational investigations of immunoassay interferences. Pathology , 45 .
  • Park, J. Y., and Kricka, L. J. (2013). Interferences in Immunoassay. The Immunoassay Handbook , 403–416.
  • EP07: Interference Testing in Clinical Chemistry. (2020). Retrieved from https://clsi.org/standards/products/method-evaluation/documents/ep07/ .
  • Gilles A, Frechin L, Natchiar K, Biondani G, Loeffelholz OV, Holvec S, Malaval JL, Winum JY, Klaholz BP, Peyron JF. Targeting the Human 80S Ribosome in Cancer: From Structure to Function and Drug Design for Innovative Adjuvant Therapeutic Strategies. Cells . 2020 Mar 5;9(3). pii: E629.
  • Coussens NP, Auld D, Roby P, Walsh J, Baell JB, Kales S, Hadian K, Dahlin JL. Compound-Mediated Assay Interferences in Homogenous Proximity Assays. Assay Guidance Manual [Internet]. Bethesda (MD): Eli Lilly & Company and the National Center for Advancing Translational Sciences; 2004-. 2020 Feb 1.
  • Use of urine organic acids method for the analysis of gamma-hydroxybutric acid (GHB): importance of urease in eliminating urea interference. Garg U, Scott D, Kiscoan M, Knoblauch J, Frazee CC 3rd, Wasserman G. Clin Toxicol (Phila). 2007;45(2):194-6.
  • Immunoglobulin G Determination in Human Serum and Milk Using an Immunosensor of New Conception Fitted with an Enzyme Probe as Transducer. Campanella L, Lelo D, Martini E, Tomassetti M. Sensors (Basel). 2008 Oct 28;8(10):6727-6746.
  • When one chip is not enough: augmenting the validity of SELDI-TOF proteomic profiles of clinical specimens. Kristina G, Radomir P, Eva B, Lenka D, Radek L, Rostislav V, Borivoj V, Dalibor V. Lab Chip. 2009 Apr 7;9(7):1014-7.

All Interference Products Brochure

Interference Testing Brochure

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Product Resources:

Manual Manual
Brochure Brochure

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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