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p70 S6 Kinase Substrate Chemicals Molecular Depot
p70 S6 Kinase Substrate Chemicals Molecular Depot
p70 S6 Kinase Substrate Chemicals Molecular Depot
p70 S6 Kinase Substrate Chemicals Molecular Depot

p70 S6 Kinase Substrate

$995.00

    Catalog Number: B2011468 (1 mg)

    p70 S6 Kinase Substrate is a high quality substrate for p70 ribosomal S6 kinase. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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    Email: info@bluetigerscientific.com

    Text/SMS: (833) 928-4437 Mon–Fri, (8 am – 8 pm PST)

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What's Included

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VR Headset

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2 Touch Controllers

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Charging Cable

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Power Adapter

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Glasses Spacer

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p70 S6 Kinase Substrate

Catalog number: B2011468
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: 1115.4 g/mol
Supplied as: Lyophilized
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: p70 S6 Kinase Substrate [KKRNRTLTV]
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References

  • Fan Y, Cheng Y, Li Y, Chen B, Wang Z, Wei T, Zhang H, Guo Y, Wang Q, Wei Y, Chen F, Sha J, Guo X, Wang L. Phosphoproteomic Analysis of Neonatal Regenerative Myocardium Revealed Important Roles of Checkpoint Kinase 1 via Activating Mammalian Target of Rapamycin C1/Ribosomal Protein S6 Kinase b-1 Pathway Circulation. 2020 May 12;141(19):1554-1569.
  • Tang G, Li S, Zhang C, Chen H, Wang N, Feng Y. Clinical efficacies, underlying mechanisms and molecular targets of Chinese medicines for diabetic nephropathy treatment and management Acta Pharm Sin B. 2021 Sep;11(9):2749-2767.
  • Yang H, Rudge DG, Koos JD, Vaidialingam B, Yang HJ, Pavletich NP. mTOR kinase structure, mechanism and regulation Nature. 2013 May 9;497(7448):217-23.
  • Li C, Ma B, Chen J, Jeong Y, Xu X. Astaxanthin Inhibits p70 S6 Kinase 1 Activity to Sensitize Insulin Signaling Mar Drugs. 2020 Sep 28;18(10):495.
  • Theodoropoulou M, Stalla GK. Somatostatin receptors: from signaling to clinical practice Front Neuroendocrinol. 2013 Aug;34(3):228-52.
  • Artemenko M, Zhong SSW, To SKY, Wong AST. p70 S6 kinase as a therapeutic target in cancers: More than just an mTOR effector Cancer Lett. 2022 Jun 1;535:215593.
  • Yang H, Jiang X, Li B, Yang HJ, Miller M, Yang A, Dhar A, Pavletich NP. Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40 Nature. 2017 Dec 21;552(7685):368-373.
  • Ip CK, Wong AS. Exploiting p70 S6 kinase as a target for ovarian cancer Expert Opin Ther Targets. 2012 Jun;16(6):619-30.
  • Bhatt AP, Wong JP, Weinberg MS, Host KM, Giffin LC, Buijnink J, van Dijk E, Izumiya Y, Kung HJ, Temple BR, Damania B. A viral kinase mimics S6 kinase to enhance cell proliferation Proc Natl Acad Sci U S A. 2016 Jul 12;113(28):7876-81.

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    Product Use & Eligibility
    Products are for in vitro research use only (RUO). They are not intended for human or animal use, diagnosis, therapy, resale to consumers, or residential delivery. Sales are limited to verified business addresses.

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    All purchases are prepaid and non-refundable once confirmed. Pricing is in USD and subject to change without notice.

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    Blue Tiger Scientific and Molecular Depot LLC are not responsible for any damages resulting from product use or misuse.

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    By ordering, you waive all claims arising from use of Molecular Depot products.

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    MD 2000: Non-regulated use, limited change notification

    MD 3000: Regulated use, enhanced quality standards

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Product Resources:

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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