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Methyl-beta-cyclodextrin Solution 10% (w/v) Chemicals Molecular Depot
Methyl-beta-cyclodextrin Solution 10% (w/v) Chemicals Molecular Depot
Methyl-beta-cyclodextrin Solution 10% (w/v) Chemicals Molecular Depot
Methyl-beta-cyclodextrin Solution 10% (w/v) Chemicals Molecular Depot

Methyl-beta-cyclodextrin Solution 10% (w/v)

$595.00

    Catalog Number: K1010005C (25 mL)

    10% Methyl-beta-cyclodextrin is an aqueous solution of the cyclic methylated dextrin of type Beta. This product has been used as versatile tools in molecular assemblies, enhancement of solubility and organic synthesis. It has also been used in a wide array of other biochemical and immunological applications. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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Methyl-beta-cyclodextrin Solution 10% (w/v)

Catalog # K1010005C
Lot # Batch Dependent
Expiration Batch Dependent
Amount 25 mL
Concentration 10% (w/v)
Supplied as Solution
Applications Solubility enhancement, molecular assemblies, organic synthesis
Storage 2–8°C
Keywords Methyl-β-cyclodextrin, Methyl-b-cyclodextrin
Grade Biotechnology grade; ultrapure water, 0.22 µm filtered

This 10% (w/v) solution of methyl-beta-cyclodextrin (MβCD) is a high-purity reagent widely used in membrane biology, drug delivery, and supramolecular chemistry. MβCD is a methylated derivative of beta-cyclodextrin that enhances the solubility of hydrophobic molecules by forming inclusion complexes. Its ability to extract cholesterol from lipid membranes has made it a critical tool in studying lipid raft dynamics and membrane protein behavior.

Formulated in ultrapure water and filtered through 0.22 µm membranes, this biotechnology-grade solution is supplied in 25 mL aliquots and stored at 2–8°C. MβCD is also used in nanoparticle formulation, antiviral research, and antimicrobial enhancement. Its methylation improves aqueous solubility and reduces crystallinity, making it suitable for both analytical and preparative workflows.

Key benefits:

  • 10% (w/v) MβCD solution for cholesterol depletion and solubility enhancement
  • Supports lipid raft studies, drug delivery, and host–guest chemistry
  • Filtered through 0.22 µm for reproducibility and purity
  • Packaged in ultrapure water; biotechnology grade
  • Compatible with pharmaceutical, biochemical, and nanomedicine workflows

Indication for Use:
This product is for Research Use Only (RUO). This product is not for administration to humans or animals. This product is not for human or veterinary diagnostic or therapeutic use.

References:
1: Mahammad S, Parmryd I. Cholesterol depletion using methyl-β-cyclodextrin.
Methods Mol Biol. 2015;1232:91-102.

2: Cai L, Lim H, Nicholas DD, Kim Y. Bio-based Preservative using Methyl-β-
cyclodextrin-Essential Oil Complexes for Wood Protection. Int J Biol Macromol.
2020 Mar 15;147:420-427.

3: Jiang Y, Liu S, Shen S, Guo H, Huang H, Wei W. Methyl-β-cyclodextrin inhibits
EV-D68 virus entry by perturbing the accumulation of virus particles and ICAM-5
in lipid rafts. Antiviral Res. 2020 Apr;176:104752.

4: Mundhara N, Majumder A, Panda D. Methyl-β-cyclodextrin, an actin
depolymerizer augments the antiproliferative potential of microtubule-targeting
agents. Sci Rep. 2019 May 21;9(1):7638.

5: Trapani A, Catalano A, Carocci A, Carrieri A, Mercurio A, Rosato A,
Mandracchia D, Tripodo G, Schiavone BIP, Franchini C, Mesto E, Schingaro E,
Corbo F. Effect of Methyl-β-Cyclodextrin on the antimicrobial activity of a new
series of poorly water-soluble benzothiazoles. Carbohydr Polym. 2019 Mar
1;207:720-728.

6: Piras AM, Fabiano A, Chiellini F, Zambito Y. Methyl-β-cyclodextrin quaternary
ammonium chitosan conjugate: nanoparticles vs macromolecular soluble complex.
Int J Nanomedicine. 2018 Apr 24;13:2531-2541.

7: Huang J, Li C, Fan F, Liu N, Boadi F, Shen X, Hao B. Methyl-Beta-
Cyclodextrin-Induced Macropinocytosis Results in Increased Infection of Sf21
Cells by Bombyx Mori Nucleopolyhedrovirus. Viruses. 2019 Oct 11;11(10):937.

8: Cesari A, Piras AM, Zambito Y, Uccello Barretta G, Balzano F. 2-Methyl-β-
cyclodextrin grafted ammonium chitosan: synergistic effects of cyclodextrin host
and polymer backbone in the interaction with amphiphilic prednisolone phosphate
salt as revealed by NMR spectroscopy. Int J Pharm. 2020 Sep 25;587:119698.

9: Lu N, Liu Y. Structural, physicochemical, and functional (antioxidant-
antimicrobial) properties of 2-O-methyl-β-cyclodextrin inclusion with hexahydro-
β-acids in chitosan films. Colloids Surf B Biointerfaces. 2020 Jul;191:111002.
10: Elamin KM, Yamashita Y, Higashi T, Motoyama K, Arima H. Supramolecular
Complex of Methyl-β-cyclodextrin with Adamantane-Grafted Hyaluronic Acid as a
Novel Antitumor Agent. Chem Pharm Bull (Tokyo). 2018 Mar 1;66(3):277-285.

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    All purchases are prepaid and non-refundable once confirmed. Pricing is in USD and subject to change without notice.

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    Blue Tiger Scientific and Molecular Depot LLC are not responsible for any damages resulting from product use or misuse.

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    By ordering, you waive all claims arising from use of Molecular Depot products.

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Product Resources:

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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