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(2-hydroxypropyl)-alpha-cyclodextrin Solution 10% (w/v) Chemicals Molecular Depot
(2-hydroxypropyl)-alpha-cyclodextrin Solution 10% (w/v) Chemicals Molecular Depot
(2-hydroxypropyl)-alpha-cyclodextrin Solution 10% (w/v) Chemicals Molecular Depot
(2-hydroxypropyl)-alpha-cyclodextrin Solution 10% (w/v) Chemicals Molecular Depot

(2-hydroxypropyl)-alpha-cyclodextrin Solution 10% (w/v)

$595.00

    Catalog Number: K1010005B (25 mL)

    (2-hydroxypropyl)-alpha-cyclodextrin Solution 10% (w/v) is an aqueous solution of the cyclic hydroxylated dextrin of type Alpha. This product has been used as versatile tools in molecular assemblies, enhancement of solubility and organic synthesis. It has also been used in a wide array of other biochemical and immunological applications. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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VR Headset

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2 Touch Controllers

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Charging Cable

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(2-hydroxypropyl)-alpha-cyclodextrin Solution 10% (w/v)

Catalog # K1010005B
Lot # Batch Dependent
Expiration Batch Dependent
Amount 25 mL
Concentration 10% (w/v)
Supplied as Solution
Applications Solubility enhancement, molecular assemblies, organic synthesis
Storage 2–8°C
Keywords HPαCD, α‐HPCD, 2‐hydroxypropyl‐α‐CD, HP-α-CD, 2OHpαCD
Grade Biotechnology grade; ultrapure water, 0.22 µm filtered

This 10% (w/v) solution of (2-hydroxypropyl)-alpha-cyclodextrin (HPαCD) is a versatile reagent used in solubility enhancement, host–guest chemistry, and formulation development. HPαCD is a modified cyclic oligosaccharide that improves the aqueous solubility of poorly soluble compounds by forming inclusion complexes. Its alpha-cyclodextrin backbone offers a smaller cavity size, making it ideal for encapsulating low-molecular-weight hydrophobic guests.

Supplied as a clear, ready-to-use solution in ultrapure water, this reagent is filtered through 0.22 µm membranes and packaged in 25 mL aliquots. It is widely used in pharmaceutical formulation, supramolecular chemistry, and analytical method development. Researchers working in drug delivery, molecular encapsulation, and solubilization of bioactive compounds will find this reagent highly effective and reproducible.

Key benefits:

  • 10% (w/v) HPαCD solution for solubility enhancement
  • Supports host–guest chemistry and molecular encapsulation
  • Filtered through 0.22 µm for analytical compatibility
  • Ideal for pharmaceutical, biochemical, and synthetic workflows
  • Supplied in ultrapure water; biotechnology grade

Indication for Use:
This product is for Research Use Only (RUO). This product is not for administration to humans or animals. This product is not for human or veterinary diagnostic or therapeutic use.

References:
1: Hoque S, Kondo Y, Sakata N, Yamada Y, Fukaura M, Higashi T, Motoyama K, Arima
H, Higaki K, Hayashi A, Komiya T, Ishitsuka Y, Irie T. Differential Effects of
2-Hydroxypropyl-Cyclodextrins on Lipid Accumulation in Npc1-Null Cells.
Int J Mol Sci. 2020 Jan 30;21(3):898.

2: Tomono K, Goto H, Suzuki T, Ueda H, Nagai T, Watanabe J. Interaction of
iodine with 2-hydroxypropyl-alpha-cyclodextrin and its bactericidal activity.
Drug Dev Ind Pharm. 2002 Nov;28(10):1303-9.

3: Motoyama K, Hashimoto Y, Hirayama F, Uekama K, Arima H. Inhibitory effects of
2,6-di-O-methyl-alpha-cyclodextrin on poly I:C signaling in macrophages. Eur J
Pharm Sci. 2009 Feb 15;36(2-3):285-91.

4: Holm R, Schönbeck C, Askjær S, Jensen H, Westh P, Østergaard J. Complexation
of tauro- and glyco-conjugated bile salts with α-cyclodextrin and hydroxypropyl-
α-cyclodextrin studied by affinity capillary electrophoresis and molecular
modelling. J Sep Sci. 2011 Nov;34(22):3221-30.

5: Zarzycki PK, Ohta H, Saito Y, Jinno K. Interaction of native alpha-
cyclodextrin, beta-cyclodextrin and gamma-cyclodextrin and their hydroxypropyl
derivatives with selected organic low molecular mass compounds at elevated and
subambient temperature under RP-HPLC conditions. Anal Bioanal Chem. 2008
Aug;391(8):2793-801.

6: Liu B, Li W, Nguyen TA, Zhao J. Empirical, thermodynamic and quantum-chemical
investigations of inclusion complexation between flavanones and
(2-hydroxypropyl)-cyclodextrins. Food Chem. 2012 Sep 15;134(2):926-32.

7: Terekhova IV, Scriba GK. Study on complex formation of biologically active
pyridine derivatives with cyclodextrins by capillary electrophoresis. J Pharm
Biomed Anal. 2007 Nov 30;45(4):688-93.

8: Rizzi V, Matera S, Semeraro P, Fini P, Cosma P. Interactions between
4-thiothymidine and water-soluble cyclodextrins: Evidence for supramolecular
structures in aqueous solutions. Beilstein J Org Chem. 2016 Mar 21;12:549-63.

9: Warne LN, Beths T, Whittem T, Carter JE, Bauquier SH. A review of the
pharmacology and clinical application of alfaxalone in cats. Vet J. 2015
Feb;203(2):141-8.
10: Kimura K, Hirayama F, Arima H, Uekama K. Solid-state 13C nuclear magnetic
resonance spectroscopic study on amorphous solid complexes of tolbutamide with
2-hydroxypropyl-alpha- and -beta-cyclodextrins. Pharm Res. 1999
Nov;16(11):1729-34.

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    Product Use & Eligibility
    Products are for in vitro research use only (RUO). They are not intended for human or animal use, diagnosis, therapy, resale to consumers, or residential delivery. Sales are limited to verified business addresses.

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    All purchases are prepaid and non-refundable once confirmed. Pricing is in USD and subject to change without notice.

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    Blue Tiger Scientific and Molecular Depot LLC are not responsible for any damages resulting from product use or misuse.

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    By ordering, you waive all claims arising from use of Molecular Depot products.

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    Shipping Exceptions FedEx may impose restrictions or delays due to package size, weight, destination, or service availability. Blue Tiger Scientific is not liable for delays beyond our control.

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    Quality System (MD Levels)
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    MD 1000: Non-regulated use, no change notification

    MD 2000: Non-regulated use, limited change notification

    MD 3000: Regulated use, enhanced quality standards

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Product Resources:

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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