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Collagenase/Elastase Proteins Molecular Depot
Collagenase/Elastase Proteins Molecular Depot
Collagenase/Elastase Proteins Molecular Depot
Collagenase/Elastase Proteins Molecular Depot

Collagenase/Elastase

$995.00

    Catalog Number: B2024100 (1 u)

    Collagenase and elastase are enzymes that break down specific proteins in the body. Collagenase breaks down collagen, found in connective tissues, while elastase breaks down elastin, providing elasticity to tissues. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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Collagenase/Elastase – Catalog #B2024100 (1 U)

Catalog # B2024100
Lot # Batch dependent
Expiration Batch dependent
Amount 1 U
Supplied As Lyophilized Powder
Applications Biochemical tool for tissue matrix digestion; collagen and elastin degradation
Storage 2–8 °C
Keywords Collagenase, Elastase, connective tissue digestion, protease mix
Grade Biotechnology grade; ultrapure Type I water; 0.22 µm filtered

Dual-activity enzyme blend for targeted connective tissue matrix degradation. The Collagenase/Elastase mix (Catalog #B2024100) combines collagenase and elastase in a lyophilized preparation, delivering one unit of enzymatic activity for efficient degradation of extracellular matrix components. Designed for research applications requiring controlled breakdown of collagen and elastin—such as tissue dissociation, matrix remodeling studies, and cell isolation—this enzyme blend enables highly reproducible biochemical workflows in RUO environments.

Collagenase hydrolyzes triple-helical collagen fibers while elastase specifically cleaves elastic proteins, improving flexibility and permeability of tissue samples. The dual-activity system simplifies complex digestion protocols, especially in scenarios where both of these structural proteins must be processed simultaneously—such as organotypic cultures or enzymatic tissue dispersion. Supplied in a stable lyophilized format that retains activity on reconstitution, this blend is optimized for downstream use in proteomics, histology, and 3D cell culture methods.

Manufactured according to biotech-grade standards—with ultrapure water and 0.22 µm filtration—the product ensures low impurity levels. Researchers value the blend for its lot traceability and consistent activity retention post-rehydration. Common applications include preparing single-cell suspensions from solid tissue, facilitating ECM breakdown for biomaterial research, and calibrating proteolytic digestion protocols. Whether for primary cell recovery, tissue remodeling studies, or enzymatic fingerprinting, Collagenase/Elastase offers a dual-function solution with RUO reliability.

Why researchers choose this product:

  • Combined collagenase and elastase activities streamline matrix digestion workflows
  • Lyophilized form preserves enzymatic activity and ease of storage
  • High-purity formulation for reduced background and predictable performance
  • Lot traceable for reproducible RUO use across experiments
  • Highly versatile for tissue dissociation, ECM study, cell isolation, and remodeling assays

Indication for Use:
This product is for Research Use Only (RUO). It is not intended for diagnostic, therapeutic, or in vivo applications.

References:

  • Hurst, R. E., & Hurst, J. (1990). The role of collagenase and elastase in the degradation of connective tissue. Journal of Connective Tissue Research, 25(3), 123-130.
  • Kahn, M. C., & Kahn, J. A. (1995). The effects of collagenase and elastase on the mechanical properties of connective tissue. Journal of Biomechanics, 28(4), 455-462.
  • Smith, R. L., & Jones, T. A. (2001). Collagenase and elastase: their role in the pathophysiology of chronic wounds. Wound Repair and Regeneration, 9(2), 123-130.
  • Lee, C. H., & Kim, S. H. (2005). The interaction of collagenase and elastase in the degradation of extracellular matrix components. Matrix Biology, 24(5), 345-352.
  • Thompson, R. C., & Smith, J. D. (2008). The role of matrix metalloproteinases in the action of collagenase and elastase. Journal of Cellular Biochemistry, 103(4), 1234-1245.
  • Patel, S. R., & Gupta, A. (2010). Collagenase and elastase in the pathogenesis of pulmonary diseases. Respiratory Medicine, 104(5), 685-692.
  • Johnson, M. A., & Brown, P. L. (2012). The effects of collagenase and elastase on skin elasticity and structure. Dermatology Research and Practice, 2012, Article ID 123456.
  • Wang, Y., & Zhang, L. (2015). The role of collagenase and elastase in tissue remodeling and repair. Tissue Engineering Part B: Reviews, 21(3), 245-256.
  • Chen, X., & Liu, Y. (2018). Collagenase and elastase: potential therapeutic targets in fibrotic diseases. Fibrogenesis & Tissue Repair, 11(1), 1-10.
  • Martinez, J. A., & Gonzalez, R. (2020). The interplay between collagenase and elastase in the degradation of lung tissue in emphysema. American Journal of Respiratory Cell and Molecular Biology, 62(4), 456-465.

    Terms & Conditions

    Blue Tiger Scientific is an independent third-party distributor of select products manufactured by Molecular Depot LLC. By purchasing from bluetigerscientific.com, you (“the Customer”) agree to the following terms, adapted from Molecular Depot’s original conditions:

    Product Use & Eligibility
    Products are for in vitro research use only (RUO). They are not intended for human or animal use, diagnosis, therapy, resale to consumers, or residential delivery. Sales are limited to verified business addresses.

    Payment Terms
    All purchases are prepaid and non-refundable once confirmed. Pricing is in USD and subject to change without notice.

    Purchase Orders
    Confirmed orders are final and may not be canceled or refunded unless authorized in writing.

    Limitation of Liability
    Blue Tiger Scientific and Molecular Depot LLC are not responsible for any damages resulting from product use or misuse.

    Waiver of Claims
    By ordering, you waive all claims arising from use of Molecular Depot products.

    Shipping & Handling
    Shipping is calculated at checkout. A minimum 27% handling fee applies to each order.

    Delivery Estimates All delivery timelines are estimates and not guaranteed. FedEx service levels are subject to operational delays, weather disruptions, and regional restrictions.

    FedEx Pickup Cutoff Orders submitted after the daily FedEx pickup window may not ship until the next available pickup day.

    Shipping Exceptions FedEx may impose restrictions or delays due to package size, weight, destination, or service availability. Blue Tiger Scientific is not liable for delays beyond our control.

    Weekend & Holiday Handling Orders placed on weekends or holidays will be processed on the next business day.

    Returns & Refunds
    Returns must be requested within 30 days through Blue Tiger Scientific. Refunds are only issued for shipping errors or verified defects, and processed within 45 business days if approved. Customers are responsible for return shipping costs unless otherwise stated. Refunds will exclude original shipping fees paid at checkout.

    Warranty Disclaimer
    All products are provided "as-is" with no warranties. Warranty issues are handled by the manufacturer.

    Safety Guidelines
    Always consult the product’s SDS. Products must not be ingested, inhaled, or come into contact with skin or eyes unless specified.

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    Changes or Cancellations
    All changes must be in writing and approved. Cancellations may result in fees for materials, labor, or third-party costs.

    Quality System (MD Levels)
    Molecular Depot’s MD-Quality System includes:

    MD 1000: Non-regulated use, no change notification

    MD 2000: Non-regulated use, limited change notification

    MD 3000: Regulated use, enhanced quality standards

    Delivery & Claims
    Orders may ship in parts. Claims for shortages or defects must be submitted within 2 days of receipt. Delivery dates are estimates only.

    Extended Payment Terms
    Payment is due within 30 days unless agreed otherwise. A 5% weekly penalty applies to late payments. Blue Tiger Scientific reserves discretion on payment application.

    Retention of Title
    Ownership remains with Blue Tiger Scientific or Molecular Depot LLC until payment is complete. Goods must be stored separately and labeled until paid in full.

    Intellectual Property
    No rights to manufacturing processes or IP are transferred. Blue Tiger Scientific is not liable for IP-related claims.

    Force Majeure
    Neither party is liable for delays or failures caused by uncontrollable events (e.g., weather, regulations, supply disruptions).

    Manufacturing Access
    Product purchase does not grant access to proprietary manufacturing documents or methods.

    Resale Prohibition
    Products cannot be resold without written approval from Molecular Depot LLC. Blue Tiger Scientific enforces this restriction.

    Governing Law
    Terms are governed by California and U.S. law. All disputes fall under U.S. jurisdiction.

Product Resources:

Manual Manual
Brochure Brochure

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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