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Vitamin B12 Biotin Conjugate Chemicals Molecular Depot
Vitamin B12 Biotin Conjugate Chemicals Molecular Depot
Vitamin B12 Biotin Conjugate Chemicals Molecular Depot
Vitamin B12 Biotin Conjugate Chemicals Molecular Depot

Vitamin B12 Biotin Conjugate

$842.00

    Catalog Number: B2010608 (1 mg)

    Vitamin B12 Biotin Conjugate is a highly pure biotinylated derivative of Vitamin B12 containing a PEG linkage. This product has been used as versatile molecule used in the study of the metabolism of vitamin B12 as well as the development of vitamin B12 assays. It has also been used in a wide array of other biochemical and immunological applications. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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Vitamin B12 Biotin Conjugate

Catalog number: B2010608
Lot number: Batch Dependent
Expiration date: Batch Dependent
Amount: 1 mg
Concentration: 5.0 mg/mL
Supplied as: Solution
Applications: Versatile molecule used in the study of vitamin B12 metabolism and development of vitamin B12 assays.
Storage: −20°C
Keywords: Biotin PEG Vitamin B12, Cobalamin PEG Biotin, Cyanocobalamin PEG Biotin
Grade: Biotechnology grade. All products are highly pure. Solutions made with Type I ultrapure water (resistivity >18 MΩ·cm), filtered through 0.22 µm.

Vitamin B12 Biotin Conjugate is a biotechnology-grade reagent designed for advanced assay development and metabolic research. Supplied as a 1 mg solution at 5.0 mg/mL concentration, this conjugate combines cyanocobalamin (vitamin B12) with biotin via a PEG linker, enabling high-affinity binding to streptavidin-coated surfaces. It is ideal for use in ELISA, CLIA, and biosensor platforms focused on vitamin B12 quantification, transport studies, and receptor-ligand interactions.

Researchers in nutritional biochemistry, clinical diagnostics, and molecular biology rely on biotinylated conjugates to enhance assay sensitivity and streamline detection workflows. This reagent supports robust signal generation and consistent performance across manual and automated systems. Filtered through 0.22 µm membranes and prepared with ultrapure water, it ensures high purity and minimal background interference. Stored at –20°C, it maintains long-term stability for repeated use in high-throughput and precision applications.

Key benefits:

  • Biotinylated vitamin B12 for streptavidin-based assay platforms

  • Supplied as a 1 mg solution at 5.0 mg/mL concentration

  • Supports ELISA, CLIA, and metabolic pathway research

  • Filtered through 0.22 µm membranes using ultrapure water

  • Stored at –20°C for long-term reagent integrity

Products are for in vitro research use only (RUO).

References

  • Bahadir A, Reis PG, Erduran E. Oral vitamin B12 treatment is effective for children with nutritional vitamin B12 deficiency. J Paediatr Child Health. 2014 Sep;50(9):721-5.
  • Anaya-Loyola MA, Brito A, Villalpando S, Allen LH. Prevalence of low serum vitamin B12 in Mexican children and women: results from the first National Nutrition Survey (1999) as a basis for interventions and progress. Int J Vitam Nutr Res. 2020 Jun;90(3-4):325-332.
  • Serraj K, Mecili M, Housni I, Andrès E. Hypervitaminémie B12: physiopathologie et intérêt en pratique clinique. Presse Med. 2011 Dec;40(12 Pt 1):1120-7.
  • Guilland JC, Aimone-Gastin I. Vitamine B12 (cobalamines). Rev Prat. 2013 Oct;63(8):1085-7, 1089-90.
  • Podzolkov VI et al. Hypervitaminosis B12 – a new marker and predictor of prognostically unfavorable diseases. Ter Arkh. 2019 Aug 15;91(8):160-167.
  • Obeid R et al. Serum vitamin B12 not reflecting vitamin B12 status in patients with type 2 diabetes. Biochimie. 2013 May;95(5):1056-61.
  • Shekoohi N et al. Smoking discriminately changes the serum active and non-active forms of vitamin B12. Acta Med Iran. 2017 Jun;55(6):389-394.
  • Wolffenbuttel BHR et al. Relationship between serum B12 concentrations and mortality: experience in NHANES. BMC Med. 2020 Oct 9;18(1):307.
  • Layden AJ et al. Vitamin B12 and placental expression of transcobalamin in pregnant adolescents. Placenta. 2016 Sep;45:1-7.
  • Naik S, Mahalle N, Bhide V. Identification of vitamin B12 deficiency in vegetarian Indians. Br J Nutr. 2018 Mar;119(6):629-635.

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Product Resources:

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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