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Vitamin B12 Alkaline Phosphatase Conjugate Proteins Molecular Depot
Vitamin B12 Alkaline Phosphatase Conjugate Proteins Molecular Depot
Vitamin B12 Alkaline Phosphatase Conjugate Proteins Molecular Depot
Vitamin B12 Alkaline Phosphatase Conjugate Proteins Molecular Depot

Vitamin B12 Alkaline Phosphatase Conjugate

$813.00

    Catalog Number: B2010399 (0.1 mg)

    Vitamin B12 Alkaline Phosphatase Conjugate (0.1 mg) consists of a concentrated solution of Alkaline Phosphatase (AP, ALP) conjugated to Vitamin B12. This product has been used as a molecular tool in the study of the metabolism of vitamin B12 as well as the development of vitamin B12 detection methods. It supplied as a solution. Custom bulk orders of this product are available upon request.

    Products are for in vitro research use only (RUO).

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What's Included

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VR Headset

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2 Touch Controllers

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Charging Cable

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Power Adapter

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Vitamin B12 Alkaline Phosphatase Conjugate (High Specificity)

Catalog number: B2010399
Lot number: Batch Dependent
Expiration date: Batch Dependent
Amount: 0.1 mg
Concentration: 1 mg/mL
Supplied as: Liquid Solution
Appearance: Clear Solution
Storage: –20°C
Keywords: Vitamin B12 Alkaline Phosphatase, Alkaline Phosphatase conjugated to Vitamin B12, Vitamin B12-AP conjugate, Vitamin B12 [AP], Vitamin B12 ALP-Conjugated, Cobalamin AP Conjugate

Vitamin B12 Alkaline Phosphatase Conjugate is a high-specificity reagent designed for vitamin B12-targeted detection and assay development. This conjugate consists of vitamin B12 covalently linked to Alkaline Phosphatase (AP), forming a clear, stable solution suitable for ELISA, biosensor calibration, and cobalamin-binding protein studies. Supplied at 1 mg/mL in liquid format, this reagent supports a wide range of biochemical and diagnostic workflows involving vitamin B12 metabolism, deficiency screening, and receptor-ligand interactions.

The AP enzyme provides a robust signal amplification mechanism, making this conjugate ideal for colorimetric and chemiluminescent assays. Researchers working in nutritional biochemistry, neurodegenerative disease research, and therapeutic monitoring rely on B12-linked conjugates to study uptake, transport, and bioavailability of cobalamin and its derivatives. This reagent is particularly useful in screening platforms for B12-binding proteins, evaluating B12 stability under various conditions, and developing targeted delivery systems.

Vitamin B12 plays a central role in DNA synthesis, red blood cell formation, and neurological function. Its active forms—methylcobalamin and adenosylcobalamin—are essential cofactors in homocysteine metabolism and fatty acid breakdown. This conjugate enables precise tracking and quantification of B12 interactions in vitro, with high specificity and minimal background interference.

Key benefits:

  • Vitamin B12 conjugated to Alkaline Phosphatase for signal amplification
  • Clear, stable solution suitable for ELISA and receptor-binding assays
  • Supports B12 metabolism, deficiency screening, and cobalamin-binding studies
  • Compatible with colorimetric and chemiluminescent detection platforms
  • Supplied at 1 mg/mL; store at –20°C to maintain activity
  • Biotechnology grade; filtered through 0.22 μm membranes

Products are for in vitro research use only (RUO).

References

  • Thakkar K, Billa G. Treatment of vitamin B12 deficiency—methylcobalamine, cyancobalamine, or hydroxocobalamin? Eur J Clin Nutr. 2015 Jan;69(1):1–2.
  • Hvas AM, Nexo E. Diagnosis and treatment of vitamin B12 deficiency—an update. Haematologica. 2006 Nov;91(11):1506–1512.
  • Watanabe F et al. Biologically active vitamin B12 compounds in foods. J Agric Food Chem. 2013 Jul 17;61(28):6769–6775.
  • Wang JY et al. Vitamin B12 for herpetic neuralgia: meta-analysis. Complement Ther Med. 2018 Dec;41:277–282.
  • Kräutler B. Biochemistry of B12-cofactors in human metabolism. Subcell Biochem. 2012;56:323–346.
  • Miles LM et al. Impact of baseline B12 status on neurologic function. Eur J Clin Nutr. 2017 Oct;71(10):1166–1172.
  • Watanabe F et al. Bioavailability of B12 from edible algae. J Nutr Sci Vitaminol (Tokyo). 2002 Oct;48(5):325–331.
  • Chalella Mazzocato M et al. Stability of B12 via microencapsulation. Food Res Int. 2019 Dec;126:108663.
  • Andrès E et al. Oral and nasal B12 therapy in the elderly. QJM. 2020 Jan 1;113(1):5–15.

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    Blue Tiger Scientific is an independent third-party distributor of select products manufactured by Molecular Depot LLC. By purchasing from bluetigerscientific.com, you (“the Customer”) agree to the following terms, adapted from Molecular Depot’s original conditions:

    Product Use & Eligibility
    Products are for in vitro research use only (RUO). They are not intended for human or animal use, diagnosis, therapy, resale to consumers, or residential delivery. Sales are limited to verified business addresses.

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Product Resources:

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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