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Tacrolimus Biotin Conjugate Solution Chemicals Molecular Depot
Tacrolimus Biotin Conjugate Solution Chemicals Molecular Depot
Tacrolimus Biotin Conjugate Solution Chemicals Molecular Depot
Tacrolimus Biotin Conjugate Solution Chemicals Molecular Depot

Tacrolimus Biotin Conjugate Solution

$2,195.00

    Catalog #: C2010006 (1 mg or 5 mg)

    Tacrolimus Biotin Conjugate Solution is a concentrated solution of Tacrolimus (FK506) conjugated to Biotin through a PEG linker. Dilutions of the provided conjugate can be made in DMSO. The provided conjugate can be used in the research of Tacrolimus detection methods that include ELISA, Western Blots and other research applications. Custom bulk orders of this product are available upon request.

    Products are for in vitro research use only (RUO).

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Tacrolimus Biotin Conjugate Solution

Catalog number: C2010006
Lot number: Batch Dependent
Expiration date: Batch Dependent
Purity: > 95% by HPLC
Concentration: 10 mg/mL (in DMSO)
Package Size: 1 mg and 5 mg
Appearance: Yellow Solution
Storage: −20°C. Avoid repeated freeze-thaw.
Other names: Biotin-Tacrolimus, Biotin conjugated to Tacrolimus, FK506-Biotin, Biotin-FK506, Biotinylated Tacrolimus, Biotinylated FK506
Keywords: Biotin conjugate, Tacrolimus 32, Tacrolimus, FK-506, Fujimycin, Prograf, Advagraf, Protopic

Tacrolimus Biotin Conjugate Solution is a high-purity reagent designed for immunoassay development, drug-binding studies, and mechanistic research in immunosuppressive pharmacology. This conjugate links tacrolimus (FK506) to biotin, enabling high-affinity capture via streptavidin-coated surfaces. Supplied in DMSO at 10 mg/mL, it supports workflows in transplant immunology, T-cell signaling, and calcineurin pathway analysis.

Researchers investigating tacrolimus pharmacokinetics, drug interactions, or therapeutic monitoring rely on biotinylated conjugates for assay calibration and target validation. With >95% purity by HPLC and a stable yellow solution format, this reagent is compatible with ELISA, SPR, and biosensor platforms. It is available in 1 mg and 5 mg formats and should be stored at −20°C to preserve integrity. Avoid repeated freeze-thaw cycles to maintain optimal binding performance.

Key benefits:

  • Biotinylated tacrolimus for streptavidin-based capture and detection
  • Supplied at 10 mg/mL in DMSO for solubility and stability
  • High purity (>95%) confirmed by HPLC
  • Supports ELISA, SPR, and immunosuppressive drug research
  • Available in 1 mg and 5 mg formats

Products are for in vitro research use only (RUO).

References

  • Brunet, M., Plana, J. C., and Rimola, A. (2001). Tacrolimus. Madrid: Drug Farma.
  • Goto, T., and Nakagawa, H. (2004). Development of Tacrolimus Ointment. Tacrolimus Ointment, 81–98.
  • Raptis, D., and Pramateftakis, M.-G. (2013). Tacrolimus: Effectiveness, safety and drug interactions. New York: Nova Biomedical.
  • Plosker, G. L., and Foster, R. H. (2001). Tacrolimus a further update of its pharmacology and therapeutic use in the management of organ transplantation. Auckland: ADIS International.
  • Kaplan, B., Burckart, G. J., and Lakkis, F. G. (2012). Immunotherapy in transplantation: principles and practice. Chichester, West Sussex, UK: Wiley Blackwell.
  • Katoh N, Ohya Y, Ikeda M, Ebihara T, Katayama I, Saeki H, Shimojo N, Tanaka A, Nakahara T, Nagao M, Hide M, Fujita Y, Fujisawa T, Futamura M, Masuda K, Murota H, Yamamoto-Hanada K; Committee for Clinical Practice Guidelines for the Management of Atopic Dermatitis 2018, Japanasese Society of Allergology, Japanese Dermatology Association. Japanese guidelines for atopic dermatitis 2020. Allergol Int. 2020 Apr 4. pii: S1323-8930(20)30018-6.
  • Lv X, Qi J, Zhou M, Shi B, Cai C, Tang Y, Pan T, Han Y. Comparative efficacy of 20 graft-versus-host disease prophylaxis therapies for patients after hematopoietic stem-cell transplantation: A multiple-treatments network meta-analysis. Crit Rev Oncol Hematol. 2020 Mar 20;150:102944.
  • Oberbauer R, Bestard O, Furian L, Maggiore U, Pascual J, Rostaing L, Budde K. Optimization of tacrolimus in kidney transplantation: New pharmacokinetic perspectives. Transplant Rev (Orlando). 2020 Apr;34(2):100531.

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Product Resources:

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Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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