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Recombinant MAP2K1 (MEK1) Protein Proteins Molecular Depot
Recombinant MAP2K1 (MEK1) Protein Proteins Molecular Depot
Recombinant MAP2K1 (MEK1) Protein Proteins Molecular Depot
Recombinant MAP2K1 (MEK1) Protein Proteins Molecular Depot

Recombinant MAP2K1 (MEK1) Protein

$2,195.00

    Catalog Number: B2017587 (10 µg)

    Recombinant MAP2K1 (MEK1) protein is a MAP2K1 protein, also known as MEK1. MEK1 is a key enzyme involved in the mitogen-activated protein kinase (MAPK) signaling pathway, which plays a critical role in cell growth, proliferation, differentiation, and survival. Recombinant MAP2K1 protein is often used in research settings to study the function and regulation of the MAPK signaling pathway. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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What's Included

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VR Headset

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2 Touch Controllers

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Charging Cable

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Power Adapter

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Recombinant MAP2K1 (MEK1) Protein

Catalog number: B2017587
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 µg
Molecular Weight or Concentration: 46.8 kDa
Supplied as: SOLUTION
Applications: a molecular tool for various biochemical applications
Storage: -80°C
Keywords: Mitogen-Activated Protein Kinase Kinase 1
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References

  • Yamamoto T, Tsigelny IF, Götz AW, Howell SB. Cisplatin inhibits MEK1/2 Oncotarget. 2015 Sep 15;6(27):23510-22.
  • Oza JP, Aerni HR, Pirman NL, Barber KW, Ter Haar CM, Rogulina S, Amrofell MB, Isaacs FJ, Rinehart J, Jewett MC. Robust production of recombinant phosphoproteins using cell-free protein synthesis Nat Commun. 2015 Sep 9;6:8168.
  • Yun MW, Kim K, Park JY, Chung KY. Conformational Dynamics Analysis of MEK1 Using Hydrogen/Deuterium Exchange Mass Spectrometry Protein Pept Lett. 2021;28(5):481-488.
  • Gillespie-Brown J, Fuller SJ, Bogoyevitch MA, Cowley S, Sugden PH. The mitogen-activated protein kinase kinase MEK1 stimulates a pattern of gene expression typical of the hypertrophic phenotype in rat ventricular cardiomyocytes J Biol Chem. 1995 Nov 24;270(47):28092-6.
  • Hirata H, Hinoda Y, Ueno K, Shahryari V, Tabatabai ZL, Dahiya R. MicroRNA-1826 targets VEGFC, beta-catenin (CTNNB1) and MEK1 (MAP2K1) in human bladder cancer Carcinogenesis. 2012 Jan;33(1):41-8.
  • Pham CD, Arlinghaus RB, Zheng CF, Guan KL, Singh B. Characterization of MEK1 phosphorylation by the v-Mos protein Oncogene. 1995 Apr 20;10(8):1683-8.
  • Russell M, Lange-Carter CA, Johnson GL. Regulation of recombinant MEK1 and MEK2b expressed in Escherichia coli Biochemistry. 1995 May 23;34(20):6611-5.
  • Huang CY, Chou YH, Hsieh NT, Chen HH, Lee MF. MED28 regulates MEK1-dependent cellular migration in human breast cancer cells J Cell Physiol. 2012 Dec;227(12):3820-7.
  • Fleischmann J, Feichtner A, DeFalco L, Kugler V, Schwaighofer S, Huber RG, Stefan E. Allosteric Kinase Inhibitors Reshape MEK1 Kinase Activity Conformations in Cells and In Silico Biomolecules. 2021 Mar 30;11(4):518.

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    Blue Tiger Scientific is an independent third-party distributor of select products manufactured by Molecular Depot LLC. By purchasing from bluetigerscientific.com, you (“the Customer”) agree to the following terms, adapted from Molecular Depot’s original conditions:

    Product Use & Eligibility
    Products are for in vitro research use only (RUO). They are not intended for human or animal use, diagnosis, therapy, resale to consumers, or residential delivery. Sales are limited to verified business addresses.

    Payment Terms
    All purchases are prepaid and non-refundable once confirmed. Pricing is in USD and subject to change without notice.

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    Blue Tiger Scientific and Molecular Depot LLC are not responsible for any damages resulting from product use or misuse.

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    By ordering, you waive all claims arising from use of Molecular Depot products.

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    MD 1000: Non-regulated use, no change notification

    MD 2000: Non-regulated use, limited change notification

    MD 3000: Regulated use, enhanced quality standards

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Product Resources:

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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