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Recombinant Human CDK1 & Cyclin A2 Protein (Full Length, GST Tag, Active) Proteins Molecular Depot
Recombinant Human CDK1 & Cyclin A2 Protein (Full Length, GST Tag, Active) Proteins Molecular Depot

Recombinant Human CDK1 & Cyclin A2 Protein (Full Length, GST Tag, Active)

$1,795.00

    Catalog Number: B2018981 (5 µg )

    Recombinant Human CDK1 and Cyclin A2 proteins are laboratory-produced versions involved in cell cycle regulation. CDK1 is a key enzyme for cell cycle progression, while Cyclin A2 forms an active complex with CDK1. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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    Email: info@bluetigerscientific.com

    Text/SMS: (833) 928-4437 Mon–Fri, (8 am – 8 pm PST)

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What's Included

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VR Headset

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2 Touch Controllers

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Charging Cable

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Power Adapter

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Recombinant Human CDK1 & Cyclin A2 Protein (Full Length, GST Tag, Active)

Catalog number: B2018981
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 µg
Molecular Weight or Concentration: CDK1 ~59 kDa; CyclinA2 ~78 kDa
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: −80°C
Keywords: Recombinant Human CDK1 & Cyclin A2 Protein (Full Length, GST Tag), Active
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References

  • Kanakkanthara A, Jeganathan KB, Limzerwala JF, Baker DJ, Hamada M, Nam HJ, van Deursen WH, Hamada N, Naylor RM, Becker NA, Davies BA, van Ree JH, Mer G, Shapiro VS, Maher LJ 3rd, Katzmann DJ, van Deursen JM. Cyclin A2 is an RNA binding protein that controls Mre11 mRNA translation Science. 2016 Sep 30;353(6307):1549-1552.
  • Silva Cascales H, Burdova K, Middleton A, Kuzin V, Müllers E, Stoy H, Baranello L, Macurek L, Lindqvist A. Cyclin A2 localises in the cytoplasm at the S/G2 transition to activate PLK1 Life Sci Alliance. 2021 Jan 5;4(3):e202000980.
  • Katsuno Y, Suzuki A, Sugimura K, Okumura K, Zineldeen DH, Shimada M, Niida H, Mizuno T, Hanaoka F, Nakanishi M. Cyclin A-Cdk1 regulates the origin firing program in mammalian cells Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3184-9.
  • Ma HT, Tsang YH, Marxer M, Poon RY. Cyclin A2-cyclin-dependent kinase 2 cooperates with the PLK1-SCFbeta-TrCP1-EMI1-anaphase-promoting complex/cyclosome axis to promote genome reduplication in the absence of mitosis Mol Cell Biol. 2009 Dec;29(24):6500-14.
  • Luo P, Tresini M, Cristofalo V, Chen X, Saulewicz A, Gray MD, Banker DE, Klingelhutz AL, Ohtsubo M, Takihara Y, Norwood TH. Immortalization in a normal foreskin fibroblast culture following transduction of cyclin A2 or cdk1 genes in retroviral vectors Exp Cell Res. 2004 Apr 1;294(2):406-19.
  • Vitrat N, Cohen-Solal K, Pique C, Le Couedic JP, Norol F, Larsen AK, Katz A, Vainchenker W, Debili N. Endomitosis of human megakaryocytes are due to abortive mitosis Blood. 1998 May 15;91(10):3711-23.
  • Vera J, Jaumot M, Estanyol JM, Brun S, Agell N, Bachs O. Heterogeneous nuclear ribonucleoprotein A2 is a SET-binding protein and a PP2A inhibitor Oncogene. 2006 Jan 12;25(2):260-70.
  • Boratyn E, Nowak I, Karnas E, Ryszawy D, Wnuk D, Polus A, Durbas M, Horwacik I, Rokita H. MCPIP1 overexpression in human neuroblastoma cell lines causes cell-cycle arrest by G1/S checkpoint block J Cell Biochem. 2020 Jun;121(5-6):3406-3425.
  • Badie C, Itzhaki JE, Sullivan MJ, Carpenter AJ, Porter AC. Repression of CDK1 and other genes with CDE and CHR promoter elements during DNA damage-induced G(2)/M arrest in human cells Mol Cell Biol. 2000 Apr;20(7):2358-66.

    Terms & Conditions

    Blue Tiger Scientific is an independent third-party distributor of select products manufactured by Molecular Depot LLC. By purchasing from bluetigerscientific.com, you (“the Customer”) agree to the following terms, adapted from Molecular Depot’s original conditions:

    Product Use & Eligibility
    Products are for in vitro research use only (RUO). They are not intended for human or animal use, diagnosis, therapy, resale to consumers, or residential delivery. Sales are limited to verified business addresses.

    Payment Terms
    All purchases are prepaid and non-refundable once confirmed. Pricing is in USD and subject to change without notice.

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    Blue Tiger Scientific and Molecular Depot LLC are not responsible for any damages resulting from product use or misuse.

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    By ordering, you waive all claims arising from use of Molecular Depot products.

    Shipping & Handling
    Shipping is calculated at checkout. A minimum 27% handling fee applies to each order.

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    FedEx Pickup Cutoff Orders submitted after the daily FedEx pickup window may not ship until the next available pickup day.

    Shipping Exceptions FedEx may impose restrictions or delays due to package size, weight, destination, or service availability. Blue Tiger Scientific is not liable for delays beyond our control.

    Weekend & Holiday Handling Orders placed on weekends or holidays will be processed on the next business day.

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    Warranty Disclaimer
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    Always consult the product’s SDS. Products must not be ingested, inhaled, or come into contact with skin or eyes unless specified.

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    Quality System (MD Levels)
    Molecular Depot’s MD-Quality System includes:

    MD 1000: Non-regulated use, no change notification

    MD 2000: Non-regulated use, limited change notification

    MD 3000: Regulated use, enhanced quality standards

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    Intellectual Property
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    Force Majeure
    Neither party is liable for delays or failures caused by uncontrollable events (e.g., weather, regulations, supply disruptions).

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    Product purchase does not grant access to proprietary manufacturing documents or methods.

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    Products cannot be resold without written approval from Molecular Depot LLC. Blue Tiger Scientific enforces this restriction.

    Governing Law
    Terms are governed by California and U.S. law. All disputes fall under U.S. jurisdiction.

Product Resources:

Manual Manual
Brochure Brochure

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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