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Recombinant Human 5'-nucleotidase/CD73/NT5E Protein (His Tag) Proteins Molecular Depot
Recombinant Human 5'-nucleotidase/CD73/NT5E Protein (His Tag) Proteins Molecular Depot
Recombinant Human 5'-nucleotidase/CD73/NT5E Protein (His Tag) Proteins Molecular Depot
Recombinant Human 5'-nucleotidase/CD73/NT5E Protein (His Tag) Proteins Molecular Depot

Recombinant Human 5'-nucleotidase/CD73/NT5E Protein (His Tag)

$1,995.00

    Catalog Number: B2019130 (10 µg )

    Recombinant Human 5′-nucleotidase, also known as CD73 or NT5E, is an enzyme involved in purine metabolism, catalyzing the dephosphorylation of nucleotides to nucleosides. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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    Email: info@bluetigerscientific.com

    Text/SMS: (833) 928-4437 Mon–Fri, (8 am – 8 pm PST)

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What's Included

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VR Headset

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2 Touch Controllers

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Charging Cable

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Power Adapter

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Glasses Spacer

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Recombinant Human 5'-nucleotidase/CD73/NT5E Protein (His Tag)

Catalog number: B2019130
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 µg
Molecular Weight or Concentration: 59.2 kDa
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: −20°C
Keywords: CALJA Protein, Human; CD73 Protein, Human; E5NT Protein, Human; eN Protein, Human; eNT Protein, Human; NT Protein, Human; NT5 Protein, Human; NTE Protein, Human
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References

  • Yu J, Wang X, Lu Q, Wang J, Li L, Liao X, Zhu W, Lv L, Zhi X, Yu J, Jin Y, Zou Q, Ou Z, Liu X, Zhou P. Extracellular 5′-nucleotidase (CD73) promotes human breast cancer cells growth through AKT/GSK-3β/β-catenin/cyclinD1 signaling pathway Int J Cancer. 2018 Mar 1;142(5):959-967.
  • Ghoteimi R, Braka A, Rodriguez C, Cros-Perrial E, Duvauchelle V, Uttaro JP, Mathé C, Ménétrier-Caux C, Jordheim LP, Chaloin L, Peyrottes S. Second-Generation CD73 Inhibitors Based on a 4,6-Biaryl-2-thiopyridine Scaffold ChemMedChem. 2023 Apr 3;18(7):e202200594.
  • Hesse J, Rosse MK, Steckel B, Blank-Landeshammer B, Idel S, Reinders Y, Sickmann A, Sträter N, Schrader J. Mono-ADP-ribosylation sites of human CD73 inhibit its adenosine-generating enzymatic activity Purinergic Signal. 2022 Mar;18(1):115-121.
  • Knapp KM, Zebisch M, Sträter N. Crystallization and preliminary X-ray analysis of the open form of human ecto-5′-nucleotidase (CD73) Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Dec 1;68(Pt 12):1545-9.
  • Rahimova R, Fontanel S, Lionne C, Jordheim LP, Peyrottes S, Chaloin L. Identification of allosteric inhibitors of the ecto-5′-nucleotidase (CD73) targeting the dimer interface PLoS Comput Biol. 2018 Jan 29;14(1):e1005943.
  • Wu R, Chen Y, Li F, Li W, Zhou H, Yang Y, Pei Z. Effects of CD73 on human colorectal cancer cell growth in vivo and in vitro Oncol Rep. 2016 Mar;35(3):1750-6.
  • Ghoteimi R, Nguyen VT, Rahimova R, Grosjean F, Cros-Perrial E, Uttaro JP, Mathé C, Chaloin L, Jordheim LP, Peyrottes S. Synthesis of Substituted 5′-Aminoadenosine Derivatives and Evaluation of Their Inhibitory Potential toward CD73 ChemMedChem. 2019 Aug 6;14(15):1431-1443.
  • Nishimoto S, Mizuno T, Takahashi K, Nagano F, Yuzawa Y, Nishiyama A, Osafune K, Hitomi H, Nagamatsu T. CD140b and CD73 are markers for human induced pluripotent stem cell-derived erythropoietin-producing cells FEBS Open Bio. 2020 Mar;10(3):427-433.
  • Allard B, Cousineau I, Spring K, Stagg J. Measurement of CD73 enzymatic activity using luminescence-based and colorimetric assays Methods Enzymol. 2019;629:269-289.

    Terms & Conditions

    Blue Tiger Scientific is an independent third-party distributor of select products manufactured by Molecular Depot LLC. By purchasing from bluetigerscientific.com, you (“the Customer”) agree to the following terms, adapted from Molecular Depot’s original conditions:

    Product Use & Eligibility
    Products are for in vitro research use only (RUO). They are not intended for human or animal use, diagnosis, therapy, resale to consumers, or residential delivery. Sales are limited to verified business addresses.

    Payment Terms
    All purchases are prepaid and non-refundable once confirmed. Pricing is in USD and subject to change without notice.

    Purchase Orders
    Confirmed orders are final and may not be canceled or refunded unless authorized in writing.

    Limitation of Liability
    Blue Tiger Scientific and Molecular Depot LLC are not responsible for any damages resulting from product use or misuse.

    Waiver of Claims
    By ordering, you waive all claims arising from use of Molecular Depot products.

    Shipping & Handling
    Shipping is calculated at checkout. A minimum 27% handling fee applies to each order.

    Delivery Estimates All delivery timelines are estimates and not guaranteed. FedEx service levels are subject to operational delays, weather disruptions, and regional restrictions.

    FedEx Pickup Cutoff Orders submitted after the daily FedEx pickup window may not ship until the next available pickup day.

    Shipping Exceptions FedEx may impose restrictions or delays due to package size, weight, destination, or service availability. Blue Tiger Scientific is not liable for delays beyond our control.

    Weekend & Holiday Handling Orders placed on weekends or holidays will be processed on the next business day.

    Returns & Refunds
    Returns must be requested within 30 days through Blue Tiger Scientific. Refunds are only issued for shipping errors or verified defects, and processed within 45 business days if approved. Customers are responsible for return shipping costs unless otherwise stated. Refunds will exclude original shipping fees paid at checkout.

    Warranty Disclaimer
    All products are provided "as-is" with no warranties. Warranty issues are handled by the manufacturer.

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    Always consult the product’s SDS. Products must not be ingested, inhaled, or come into contact with skin or eyes unless specified.

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    All changes must be in writing and approved. Cancellations may result in fees for materials, labor, or third-party costs.

    Quality System (MD Levels)
    Molecular Depot’s MD-Quality System includes:

    MD 1000: Non-regulated use, no change notification

    MD 2000: Non-regulated use, limited change notification

    MD 3000: Regulated use, enhanced quality standards

    Delivery & Claims
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    Extended Payment Terms
    Payment is due within 30 days unless agreed otherwise. A 5% weekly penalty applies to late payments. Blue Tiger Scientific reserves discretion on payment application.

    Retention of Title
    Ownership remains with Blue Tiger Scientific or Molecular Depot LLC until payment is complete. Goods must be stored separately and labeled until paid in full.

    Intellectual Property
    No rights to manufacturing processes or IP are transferred. Blue Tiger Scientific is not liable for IP-related claims.

    Force Majeure
    Neither party is liable for delays or failures caused by uncontrollable events (e.g., weather, regulations, supply disruptions).

    Manufacturing Access
    Product purchase does not grant access to proprietary manufacturing documents or methods.

    Resale Prohibition
    Products cannot be resold without written approval from Molecular Depot LLC. Blue Tiger Scientific enforces this restriction.

    Governing Law
    Terms are governed by California and U.S. law. All disputes fall under U.S. jurisdiction.

Product Resources:

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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